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Expression and characterization of pantothenate energy-coupling factor transporters as an anti-infective drug target
Publikation
Shams A,
Bousis S,
Diamanti E,
Elgaher W,
Zeimetz L,
Haupenthal J,
slotboom d,
Hirsch A
(2024)
Protein Sci., 33, 11, 10.1002/pro.5195, 39473025
Protein Sci., 33, 11, 10.1002/pro.5195, 39473025
Drug Administration Routes Impact the Metabolism of a Synthetic Cannabinoid in the Zebrafish Larvae Model
Publikation
Park Y,
Meyer M,
Müller R,
Herrmann J
(2020)
Molecules, 25, 19, 10.3390/molecules25194474
Molecules, 25, 19, 10.3390/molecules25194474
A shift of dynamic equilibrium between the KIT active and inactive states causes drug resistance
Publikation
Srikakulam S,
Bastys T,
Kalinina O
(2020)
Proteins, 10.1002/prot.25963, 32530065
Proteins, 10.1002/prot.25963, 32530065
Consistent Prediction of Mutation Effect on Drug Binding in HIV-1 Protease Using Alchemical Calculations
Publikation
Bastys T,
Gapsys V,
Doncheva N,
Kaiser R,
Groot B,
Kalinina O
(2018)
Journal of chemical theory and computation, 14, 7, 3397-3408, 10.1021/acs.jctc.7b01109, 29847122
Journal of chemical theory and computation, 14, 7, 3397-3408, 10.1021/acs.jctc.7b01109, 29847122
Human microbial metabolite mimicry as a strategy to expand the chemical space of potential drugs
Publikation
Li H,
Ranhotra H,
Mani S,
Dvorák Z,
Sokol H,
Müller R
(2020)
Drug Discov. Today, 25, 9, 1575-1579, 10.1016/j.drudis.2020.06.007, 32562605
Drug Discov. Today, 25, 9, 1575-1579, 10.1016/j.drudis.2020.06.007, 32562605
In vitro models for evaluating safety and efficacy of novel technologies for skin drug delivery
Publikation
Planz V,
Lehr C,
Windbergs M
(2016)
Journal of Controlled Release, 242, 89-104, 10.1016/j.jconrel.2016.09.002
Journal of Controlled Release, 242, 89-104, 10.1016/j.jconrel.2016.09.002
Label-free analysis of drug delivery systems and cellular interaction studies using confocal Raman microscopy
Publikation
Kann B
(2016)
Book
Book
Combinatorial tuning of peptidic drug candidates: high-affinity matriptase inhibitors through incremental structure-guided optimization
Publikation
Fittler H,
Avrutina O,
Glotzbach B,
Empting M,
Kolmar H
(2013)
Org. Biomol. Chem., 11, 11, 1848-57, 10.1039/c3ob27469a, 23361403
Org. Biomol. Chem., 11, 11, 1848-57, 10.1039/c3ob27469a, 23361403
Biopharmaceutical in vitro characterization of CPZEN-45, a drug candidate for inhalation therapy of tuberculosis
Publikation
Salomon J,
Galeron P,
Schulte N,
Morow P,
Severynse-Stevens D,
Huwer H,
Daum N,
Lehr C,
Hickey A,
Ehrhardt C
(2013)
Therapeutic delivery, 4, 8, 915-923, 10.4155/tde.13.62
Therapeutic delivery, 4, 8, 915-923, 10.4155/tde.13.62
Pulmonary drug delivery: From generating aerosols to overcoming biological barriers-therapeutic possibilities and technological challenges
Publikation
Ruge C,
Kirch J,
Lehr C
(2013)
The Lancet Respiratory Medicine, 1, 5, 402-413, 10.1016/S2213-2600(13)70072-9, 24429205
The Lancet Respiratory Medicine, 1, 5, 402-413, 10.1016/S2213-2600(13)70072-9, 24429205