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Gesucht nach "drug". Zeige Ergebnisse 721 bis 730 von 742.

Nano-in-Microparticles for Aerosol Delivery of Antibiotic-Loaded, Fucose-Derivatized, and Macrophage-Targeted Liposomes to Combat Mycobacterial Infections: In Vitro Deposition, Pulmonary Barrier Interactions, and Targeted Delivery

Publikation
Huck B, Thiyagarajan D, Bali A, Boese A, Besecke K, Hozsa C, Gieseler R, Furch M, Carvalho-Wodarz C, Waldow F, Schwudke D, Metelkina O, Titz A, Huwer H, Schwarzkopf K, Hoppstädter J, Kiemer A, Koch M, Loretz B, Lehr C (2022)
Advanced healthcare materials, 11, 11, 10.1002/adhm.202102117, 35112802

Generative AI designs functional thiolation domains for reprogramming non-ribosomal peptide synthetases

Publikation
Bülbül E, Bang S, George K, Bianchi G, Raj P, Chung S, Pauline V, Hochstrasser R, Minas H, Elgaher W, Kany A, Hirsch A, Schmitt S, Heinz D, Kalinina O, Klakow D, Bozhüyük K (2026)
Nat Commun, 17, 1, 10.1038/s41467-026-77963-6, 42773138

Expanding the Myxochelin Natural Product Family by Nicotinic Acid Containing Congeners

Publikation
Frank N, Széles M, Akone S, Rasheed S, Hüttel S, Frewert S, Hamed M, Herrmann J, Schuler S, Hirsch A, Müller R (2021)
Molecules, 26, 16, 10.3390/molecules26164929

Protein‐Templated Hit Identification via an Ugi Four‐Component Reaction

Publikation
Mancini F, Unver M, Elgaher W, Jumde V, Alhayek A, Lukat P, Herrmann J, Witte M, Köck M, Blankenfeldt W, Müller R, Hirsch A (2020)
Chem. Eur. J., 10.1002/chem.202002250

Inhibitors of the Elastase LasB for the Treatment of Pseudomonas aeruginosa Lung Infections

Publikation
Konstantinovic J, Kany A, Alhayek A, Abdelsamie A, Sikandar A, Voos K, Yao Y, Andreas A, Shafiei R, Loretz B, Schönauer E, Bals R, Brandstetter H, Hartmann R, Ducho C, Lehr C, Beisswenger C, Müller R, Rox K, Haupenthal J, Hirsch A (2023)
ACS Cent. Sci., 9, 12, 2205-2215, 10.1021/acscentsci.3c01102, 38161367

Fighting antibiotic resistance-strategies and (pre)clinical developments to find new antibacterials

Publikation
Walesch S, Birkelbach J, Jézéquel G, Haeckl F, Hegemann J, Hesterkamp T, Hirsch A, Hammann P, Müller R (2023)
EMBO reports, 24, 1, 10.15252/embr.202256033, 36533629

Point mutations in the ygiV promoter region lead to cystobactamid resistance and reduced virulence in E. coli

Publikation
Müller R, Risch T, Kolling D, Mostert D, Seedorf T, Heimann D, Kohnhäuser D, Deschner F, Fries F, Solga D, Hilgers J, Dastbaz J, Hirsch A, Brönstrup M, Kirschning A, Herrmann J, Sieber S (2024)
Book, 10.21203/rs.3.rs-3751821/v1

Synthesis and Biological Evaluation of Novel 2-Substituted ­Analogues of (–)-Pentenomycin I

Publikation
Zisopoulou S, Bousis S, Haupenthal J, Herrmann J, Müller R, Hirsch A, Komiotis D, Gallos J, Stathakis C (2020)
Synlett, 31, 05, 475-481, 10.1055/s-0039-1690772

Development and evaluation of 2,4-disubstituted-5-aryl pyrimidine derivatives as antibacterial agents

Publikation
Khalifa H, Rasheed S, Haupenthal J, Herrmann J, Mandour Y, Abadi A, Engel M, Müller R, Hirsch A, Abdel-Halim* M, Hamed* M (2024)
Archiv der Pharmazie, 10.1002/ardp.202300656, 38304944

Genome Mining Guided Identification of the Metallophore Delftichelin A from Delftia deserti

Publikation
Kruijff M, Hiller L, Birkelbach J, Decker T, Götze S, Kochems R, Müller R, Hirsch A, Beemelmanns C (2026)
J. Nat. Prod., 89, 4, 1318-1331, 10.1021/acs.jnatprod.6c00213