![[Translate to Deutsch:]](/fileadmin/HIPS/__processed__/3/9/csm_HIPS_50243_47cfe3711c.jpg "[Translate to Deutsch:]")
Suche
Dynamic Combinatorial Chemistry Unveils Nsp10 Inhibitors with Antiviral Potential Against SARS-CoV-2
Publikation
Jumde R,
Jézéquel G,
Saramago M,
Frank N,
Adam S,
Cunha M,
Bader C,
Gunesch A,
Köhler N,
Johannsen S,
Bousis S,
Pietschmann T,
Matos R,
Müller R,
Arraiano C,
Hirsch A
(2024)
Chem. - Eur. J., 10.1002/chem.202403390, 39676060
Chem. - Eur. J., 10.1002/chem.202403390, 39676060
Innovative zinc-binding inhibitors of Legionella pneumophila ProA reduce collagen and flagellin degradation, TLR5 evasion, and human lung tissue inflammation
Publikation
Scheithauer L,
Ornago C,
Selmar J,
Schütz C,
Bianchi G,
Kiefer A,
Haupenthal J,
Dellmann A,
Huynh D,
Zhang R,
Blankenfeldt W,
Hirsch A,
Steinert M
(2025)
European journal of medicinal chemistry, 296, 10.1016/j.ejmech.2025.117832, 40479898
European journal of medicinal chemistry, 296, 10.1016/j.ejmech.2025.117832, 40479898
Unlocking the Antiviral Arsenal: Structure-Guided Optimization of Small-Molecule Inhibitors against RSV and hCoV-229E
Publikation
Karhan C,
Sake S,
Gunesch A,
Grethe C,
Hellwinkel B,
Köhler N,
Kiefer A,
Hapko U,
Kany A,
Pietschmann T,
Hirsch A
(2025)
European journal of medicinal chemistry, 10.1016/j.ejmech.2025.117282
European journal of medicinal chemistry, 10.1016/j.ejmech.2025.117282
Search for the Active Ingredients from a 2-Aminothiazole DMSO Stock Solution with Antimalarial Activity
Publikation
Ropponen H,
Bader C,
Diamanti E,
Illarionov B,
Rottmann M,
Fischer M,
Witschel M,
Müller R,
Hirsch A
(2021)
ChemMedChem, 16, 13, 2089-2093, 10.1002/cmdc.202100067, 33844432
ChemMedChem, 16, 13, 2089-2093, 10.1002/cmdc.202100067, 33844432
Dipeptidic Phosphonates: Potent Inhibitors of Pseudomonas aeruginosa Elastase B Showing Efficacy in a Murine Keratitis Model
Publikation
Kiefer A,
Schütz C,
Englisch C,
Kolling D,
Speicher S,
Kany A,
Shafiei R,
Wadood N,
Aljohmani A,
Wirschem N,
Jumde R,
Klein A,
Sikandar A,
Park Y,
Krasteva-Christ G,
Yildiz D,
Abdelsamie A,
Rox K,
Köhnke J,
Müller R,
Bischoff M,
Haupenthal J,
Hirsch A
(2025)
Adv. Sci., 10.1002/advs.202411807, 39973061
Adv. Sci., 10.1002/advs.202411807, 39973061
Engineering an Artificial Myxopyronin Derivative with Enhanced Metabolic Stability via Mutasynthesis
Publikation
Kiefer A,
Voltz A,
Scherzer D,
Reberšek R,
Kany A,
Prosser G,
Neuber M,
Reiling N,
Hirsch A,
Müller R
(2025)
JACS Au, 10.1021/jacsau.5c00950
JACS Au, 10.1021/jacsau.5c00950
Synthesis of New Cyclomarin Derivatives and Their Biological Evaluation towards Mycobacterium Tuberculosis and Plasmodium Falciparum
Publikation
Kiefer A,
Bader C,
Held J,
Esser A,
Rybniker J,
Empting M,
Müller R,
Kazmaier U
(2019)
Chem. Eur. J., 25, 37, 8894-8902, 10.1002/chem.201901640, 31012978
Chem. Eur. J., 25, 37, 8894-8902, 10.1002/chem.201901640, 31012978