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Gesucht nach "drug". Zeige Ergebnisse 701 bis 710 von 742.

N -Aryl-3-mercaptosuccinimides as Antivirulence Agents Targeting Pseudomonas aeruginosa Elastase and Clostridium Collagenases

Publikation
Konstantinovic J, Yahiaoui S, Alhayek A, Haupenthal J, Schönauer E, Andreas A, Kany A, Müller R, Koehnke J, Berger F, Bischoff M, Hartmann R, Brandstetter H, Hirsch A (2020)
J. Med. Chem., 63, 15, 8359-8368, 10.1021/acs.jmedchem.0c00584

Discovery of the first small-molecule CsrA-RNA interaction inhibitors using biophysical screening technologies

Publikation
Maurer C, Fruth M, Empting M, Avrutina O, Hossmann J, Nadmid S, Gorges J, Herrmann J, Kazmaier U, Dersch P, Muller R, Hartmann R (2016)
Future medicinal chemistry, 8, 9, 931-47, 10.4155/fmc-2016-0033, 27253623

Bacterial RNAP Inhibitors: Synthesis and Evaluation of Prodrugs of Aryl‐ureidothiophene‐carboxylic acids

Publikation
Ruthenbeck A, Elgaher W, Haupenthal J, Hartmann R, Meier C (2017)
ChemistrySelect, 2, 35, 11899-11905, 10.1002/slct.201702574

Crystobactamides

Publikation
Sascha Baumann, Jennifer Herrmann, Kathrin Mohr, Heinrich Steinmetz, Klaus Gerth, Ritesh Raju, Rolf Müller, Rolf W. Hartmann, Mostafa Hamed, Walid A. M. Elgaher, Maria Moreno, Franziska Gille, Liang Liang Wang, Andreas Kirschning, Stephan Huettel (2022)
Patent, C07C237/42; C07C237/44; C07K5/065; C07K7/06; C12N15/52; C12P13/02; A61K38/00, US11225503B2

Citraconic acid and derivatives thereof for use as a medicament

Publikation
Frank Pessler, Fangfang Chen, Moritz Winterhoff, Konrad Büssow, Wulf Blankenfeldt, Anna Hirsch, Walid A. M. Elgaher (2024)
Patent, A61K31/122; A61K31/194; A61P31/16; C07C57/42; C07C61/20; C07C69/593;, US20240368065A1

Discovery of a novel, selective CK2 inhibitor class with an unusual basic scaffold

Publikation
Khalifa H, ElHady A, Liu T, Elgaher W, Filhol-Cochet O, Cochet C, Abadi A, Hamed M, Abdel-Halim M, Engel M (2025)
European journal of medicinal chemistry, 282, 10.1016/j.ejmech.2024.117048, 39566243

Author Correction: Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways

Publikation
Kurmasheva N, Said A, Wong B, Kinderman P, Han X, Rahimic A, Kress A, Carter-Timofte M, Holm E, van der Horst D, Kollmann C, Liu Z, Wang C, Hoang H, Kovalenko E, Chrysopoulou M, Twayana K, Ottosen R, Svenningsen E, Begnini F, Kiib A, Kromm F, Weiss H, Di Carlo D, Muscolini M, Higgins M, van der Heijden M, Arulanandam R, Bardoul A, Tong T, Ozsvar A, Hou W, Schack V, Holm C, Zheng Y, Ruzek M, Kalucka J, La Vega L, Elgaher W, Korshoej A, Lin R, Hiscott J, Poulsen T, O'Neill L, Roy D, Rinschen M, van Montfoort N, Diallo J, Farin H, Alain T, Olagnier D (2024)
Nat Commun, 15, 1, 10.1038/s41467-024-55044-w, 39702301

Adaptation of a Bacterial Multidrug Resistance System Revealed by the Structure and Function of AlbA

Publikation
Sikandar A, Cirnski K, Testolin G, Volz C, Brönstrup M, Kalinina O, Müller R, Koehnke J (2018)
J. Am. Chem. Soc., 140, 48, 16641-16649, 10.1021/jacs.8b08895, 30422653

Structure-optimized truncated aptamers coupled with copper tungstate–reduced graphene oxide for multiplexed electrochemical biosensing of chlorpyrifos, diazinon, and malathion

Publikation
Almenhali A, Kanagavalli P, Elgaher W, Abd-Ellah M, Eissa S (2026)
Adv Compos Hybrid Mater, 10.1007/s42114-026-01772-0

3D bioprinting ofE. coliMG1655 biofilms on human lung epithelial cells for building complexin vitroinfection models

Publikation
Aliyazdi S, Frisch S, Hidalgo A, Frank N, Krug D, Müller R, Schaefer U, Vogt T, Loretz B, Lehr C (2023)
Biofabrication, 15, 3, 10.1088/1758-5090/acd95e, 37236174