Suche
Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections
Publikation
Wagner S,
Sommer R,
Hinsberger S,
Lu C,
Hartmann R,
Empting M,
Titz A
(2016)
Journal of medicinal chemistry, 59, 13, 5929-69, 10.1021/acs.jmedchem.5b01698, 26804741
Journal of medicinal chemistry, 59, 13, 5929-69, 10.1021/acs.jmedchem.5b01698, 26804741
Targeting extracellular lectins of Pseudomonas aeruginosa with glycomimetic liposomes
Publikation
Metelkina O,
Huck B,
O'Connor J,
Koch M,
Manz A,
Lehr C,
Titz A
(2022)
Journal of Materials Chemistry B, 10, 4, 537-548, 10.1039/d1tb02086b, 34985094
Journal of Materials Chemistry B, 10, 4, 537-548, 10.1039/d1tb02086b, 34985094
Nano-in-Microparticles for Aerosol Delivery of Antibiotic-Loaded, Fucose-Derivatized, and Macrophage-Targeted Liposomes to Combat Mycobacterial Infections: In Vitro Deposition, Pulmonary Barrier Interactions, and Targeted Delivery
Publikation
Huck B,
Thiyagarajan D,
Bali A,
Boese A,
Besecke K,
Hozsa C,
Gieseler R,
Furch M,
Carvalho-Wodarz C,
Waldow F,
Schwudke D,
Metelkina O,
Titz A,
Huwer H,
Schwarzkopf K,
Hoppstädter J,
Kiemer A,
Koch M,
Loretz B,
Lehr C
(2022)
Advanced healthcare materials, 11, 11, 10.1002/adhm.202102117, 35112802
Advanced healthcare materials, 11, 11, 10.1002/adhm.202102117, 35112802
Expanding the Myxochelin Natural Product Family by Nicotinic Acid Containing Congeners
Publikation
Frank N,
Széles M,
Akone S,
Rasheed S,
Hüttel S,
Frewert S,
Hamed M,
Herrmann J,
Schuler S,
Hirsch A,
Müller R
(2021)
Molecules, 26, 16, 10.3390/molecules26164929
Molecules, 26, 16, 10.3390/molecules26164929
Protein‐Templated Hit Identification via an Ugi Four‐Component Reaction
Publikation
Mancini F,
Unver M,
Elgaher W,
Jumde V,
Alhayek A,
Lukat P,
Herrmann J,
Witte M,
Köck M,
Blankenfeldt W,
Müller R,
Hirsch A
(2020)
Chem. Eur. J., 10.1002/chem.202002250
Chem. Eur. J., 10.1002/chem.202002250
Synthesis and Biological Evaluation of Novel 2-Substituted Analogues of (–)-Pentenomycin I
Publikation
Zisopoulou S,
Bousis S,
Haupenthal J,
Herrmann J,
Müller R,
Hirsch A,
Komiotis D,
Gallos J,
Stathakis C
(2020)
Synlett, 31, 05, 475-481, 10.1055/s-0039-1690772
Synlett, 31, 05, 475-481, 10.1055/s-0039-1690772
Advanced mutasynthesis studies on the natural α-pyrone antibiotic myxopyronin from Myxococcus fulvus
Publikation
Sahner J,
Sucipto H,
Wenzel S,
Groh M,
Hartmann R,
Müller R
(2015)
ChemBioChem, 16, 946-953, 10.1002/cbic.201402666, 25757034
ChemBioChem, 16, 946-953, 10.1002/cbic.201402666, 25757034
Inhibitors of the Elastase LasB for the Treatment of Pseudomonas aeruginosa Lung Infections
Publikation
Konstantinovic J,
Kany A,
Alhayek A,
Abdelsamie A,
Sikandar A,
Voos K,
Yao Y,
Andreas A,
Shafiei R,
Loretz B,
Schönauer E,
Bals R,
Brandstetter H,
Hartmann R,
Ducho C,
Lehr C,
Beisswenger C,
Müller R,
Rox K,
Haupenthal J,
Hirsch A
(2023)
ACS Cent. Sci., 9, 12, 2205-2215, 10.1021/acscentsci.3c01102, 38161367
ACS Cent. Sci., 9, 12, 2205-2215, 10.1021/acscentsci.3c01102, 38161367
Fighting antibiotic resistance-strategies and (pre)clinical developments to find new antibacterials
Publikation
Walesch S,
Birkelbach J,
Jézéquel G,
Haeckl F,
Hegemann J,
Hesterkamp T,
Hirsch A,
Hammann P,
Müller R
(2023)
EMBO reports, 24, 1, 10.15252/embr.202256033, 36533629
EMBO reports, 24, 1, 10.15252/embr.202256033, 36533629
Genome Mining Guided Identification of the Metallophore Delftichelin A from Delftia deserti
Publikation
Kruijff M,
Hiller L,
Birkelbach J,
Decker T,
Götze S,
Kochems R,
Müller R,
Hirsch A,
Beemelmanns C
(2026)
Journal of natural products, 10.1021/acs.jnatprod.6c00213
Journal of natural products, 10.1021/acs.jnatprod.6c00213