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A combinatorial approach for the discovery of drug-like inhibitors of 15-lipoxygenase-1
Publikation
van der Vlag R,
Guo H,
Hapko U,
Eleftheriadis N,
Monjas L,
Dekker F,
Hirsch A
(2019)
European journal of medicinal chemistry, 174, 45-55, 10.1016/j.ejmech.2019.04.021, 31026746
European journal of medicinal chemistry, 174, 45-55, 10.1016/j.ejmech.2019.04.021, 31026746
Epistatic Interactions in NS5A of Hepatitis C Virus Suggest Drug Resistance Mechanisms
Publikation
Knops E,
Sierra S,
Kalaghatgi P,
Heger E,
Kaiser R,
Kalinina O
(2018)
Genes, 9, 7, 10.3390/genes9070343, 29986475
Genes, 9, 7, 10.3390/genes9070343, 29986475
Pathoblockers or antivirulence drugs as a new option for the treatment of bacterial infections
Publikation
Calvert M,
Jumde V,
Titz A
(2018)
Beilstein journal of organic chemistry, 14, 2607-2617, 10.3762/bjoc.14.239, 30410623
Beilstein journal of organic chemistry, 14, 2607-2617, 10.3762/bjoc.14.239, 30410623
The role of mucus on drug transport and its potential to affect therapeutic outcomes
Publikation
Murgia X,
Loretz B,
Hartwig O,
Hittinger M,
Lehr C
(2018)
Advanced Drug Delivery Reviews, 124, 82-97, 10.1016/j.addr.2017.10.009, 29106910
Advanced Drug Delivery Reviews, 124, 82-97, 10.1016/j.addr.2017.10.009, 29106910
Raman microscopy for cellular investigations--From single cell imaging to drug carrier uptake visualization
Publikation
Kann B,
Offerhaus H,
Windbergs M,
Otto C
(2015)
Advanced Drug Delivery Reviews, 89, 71-90, 10.1016/j.addr.2015.02.006, 25728764
Advanced Drug Delivery Reviews, 89, 71-90, 10.1016/j.addr.2015.02.006, 25728764
The Non-Mevalonate Pathway to Isoprenoid Biosynthesis: A Potential Source of New Drug Targets
Publikation
Hirsch A,
Diederich F
(2008)
CHIMIA, 62, 4, 226-230, 10.2533/chimia.2008.226
CHIMIA, 62, 4, 226-230, 10.2533/chimia.2008.226
Clean Synthetic Strategies to Biologically Active Molecules from Lignin: A Green Path to Drug Discovery**
Publikation
Afanasenko A,
Wu X,
Santi A,
Elgaher W,
Kany A,
Shafiei R,
Schulze M,
Schulz T,
Haupenthal J,
Hirsch A,
Barta K
(2024)
Angewandte Chemie (Weinheim an der Bergstrasse, Germany), 136, 4, 10.1002/ange.202308131
Angewandte Chemie (Weinheim an der Bergstrasse, Germany), 136, 4, 10.1002/ange.202308131
Clean Synthetic Strategies to Biologically Active Molecules from Lignin: A Green Path to Drug Discovery
Publikation
Afanasenko A,
Wu X,
Santi A,
Elgaher W,
Kany A,
Shafiei R,
Schulze M,
Schulz T,
Haupenthal J,
Hirsch A,
Barta K
(2023)
Angew. Chem. Int. Ed., 10.1002/anie.202308131, 37840425
Angew. Chem. Int. Ed., 10.1002/anie.202308131, 37840425
Thermoresponsive cholesteric liquid-crystal systems doped with terpenoids as drug delivery systems for skin applications
Publikation
Nesterkina M,
Vashchenko O,
Vashchenko P,
Lisetski L,
Kravchenko I,
Hirsch A,
Lehr C
(2023)
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 10.1016/j.ejpb.2023.09.002, 37669726
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 10.1016/j.ejpb.2023.09.002, 37669726
Simulated Tempering-Enhanced Umbrella Sampling Improves Convergence of Free Energy Calculations of Drug Membrane Permeation
Publikation
Sousa C,
Becker R,
Lehr C,
Kalinina O,
Hub J
(2023)
Journal of chemical theory and computation, 19, 6, 1898-1907, 10.1021/acs.jctc.2c01162, 36853966
Journal of chemical theory and computation, 19, 6, 1898-1907, 10.1021/acs.jctc.2c01162, 36853966