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Adaptation of a Bacterial Multidrug Resistance System Revealed by the Structure and Function of AlbA
Publikation
Sikandar A,
Cirnski K,
Testolin G,
Volz C,
Brönstrup M,
Kalinina O,
Müller R,
Koehnke J
(2018)
J. Am. Chem. Soc., 140, 48, 16641-16649, 10.1021/jacs.8b08895, 30422653
J. Am. Chem. Soc., 140, 48, 16641-16649, 10.1021/jacs.8b08895, 30422653
Bacterial RNAP Inhibitors: Synthesis and Evaluation of Prodrugs of Aryl‐ureidothiophene‐carboxylic acids
Publikation
Ruthenbeck A,
Elgaher W,
Haupenthal J,
Hartmann R,
Meier C
(2017)
ChemistrySelect, 2, 35, 11899-11905, 10.1002/slct.201702574
ChemistrySelect, 2, 35, 11899-11905, 10.1002/slct.201702574
Evolution of novel antibiotic Scaffolds targeting the nucleic acid machineries RNA polymerase, DNA gyrase, and topoisomerase IV
Publikation
Elgaher W
(2016)
Thesis, 10.22028/D291-23193
Thesis, 10.22028/D291-23193
Surface plasmon resonance--more than a screening technology: insights in the binding mode of σ70:core RNAP inhibitors
Publikation
Hüsecken K,
Hinsberger S,
Elgaher W,
Haupenthal J,
Hartmann R
(2014)
Future medicinal chemistry, 6, 14, 1551-65, 10.4155/fmc.14.105, 25367390
Future medicinal chemistry, 6, 14, 1551-65, 10.4155/fmc.14.105, 25367390
Expanding the scaffold for bacterial RNA polymerase inhibitors: design, synthesis and structure–activity relationships of ureido-heterocyclic-carboxylic acids
Publikation
Elgaher W,
Fruth M,
Groh M,
Haupenthal J,
Hartmann R
(2013)
RSC Adv, 4, 5, 2177-2194, 10.1039/C3RA45820B
RSC Adv, 4, 5, 2177-2194, 10.1039/C3RA45820B
New Theophylline Derivatives
Publikation
Elgaher W
(2011)
Book
Book
Design and synthesis of some new theophylline derivatives with bronchodilator and antibacterial activities
Publikation
Hayallah A,
Elgaher W,
Salem O,
Alim A
(2011)
Arch Pharm Res, 34, 1, 3-21, 10.1007/s12272-011-0101-8, 21468910
Arch Pharm Res, 34, 1, 3-21, 10.1007/s12272-011-0101-8, 21468910
Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections
Publikation
Wagner S,
Sommer R,
Hinsberger S,
Lu C,
Hartmann R,
Empting M,
Titz A
(2016)
Journal of medicinal chemistry, 59, 13, 5929-69, 10.1021/acs.jmedchem.5b01698, 26804741
Journal of medicinal chemistry, 59, 13, 5929-69, 10.1021/acs.jmedchem.5b01698, 26804741
Targeting extracellular lectins of Pseudomonas aeruginosa with glycomimetic liposomes
Publikation
Metelkina O,
Huck B,
O'Connor J,
Koch M,
Manz A,
Lehr C,
Titz A
(2022)
Journal of Materials Chemistry B, 10, 4, 537-548, 10.1039/d1tb02086b, 34985094
Journal of Materials Chemistry B, 10, 4, 537-548, 10.1039/d1tb02086b, 34985094
Nano-in-Microparticles for Aerosol Delivery of Antibiotic-Loaded, Fucose-Derivatized, and Macrophage-Targeted Liposomes to Combat Mycobacterial Infections: In Vitro Deposition, Pulmonary Barrier Interactions, and Targeted Delivery
Publikation
Huck B,
Thiyagarajan D,
Bali A,
Boese A,
Besecke K,
Hozsa C,
Gieseler R,
Furch M,
Carvalho-Wodarz C,
Waldow F,
Schwudke D,
Metelkina O,
Titz A,
Huwer H,
Schwarzkopf K,
Hoppstädter J,
Kiemer A,
Koch M,
Loretz B,
Lehr C
(2022)
Advanced healthcare materials, 11, 11, 10.1002/adhm.202102117, 35112802
Advanced healthcare materials, 11, 11, 10.1002/adhm.202102117, 35112802