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Double conjugate addition of dithiols to propargylic carbonyl systems to generate protected 1,3-dicarbonyl compounds
Publikation
Sneddon H,
van den Heuvel A,
Hirsch A,
Booth R,
Shaw D,
Gaunt M,
Ley S
(2006)
The Journal of organic chemistry, 71, 7, 2715-25, 10.1021/jo052514s, 16555825
The Journal of organic chemistry, 71, 7, 2715-25, 10.1021/jo052514s, 16555825
pH-Responsive Dynaplexes as Potent Apoptosis Inductors by Intracellular Delivery of Survivin siRNA
Publikation
Liu Y,
Ashmawy S,
Latta L,
Weiss A,
Kiefer A,
Nasr S,
Loretz B,
Hirsch A,
Lee S,
Lehr C
(2023)
Biomacromolecules, 24, 8, 3742-3754, 10.1021/acs.biomac.3c00424, 37523746
Biomacromolecules, 24, 8, 3742-3754, 10.1021/acs.biomac.3c00424, 37523746
N -Aryl-3-mercaptosuccinimides as Antivirulence Agents Targeting Pseudomonas aeruginosa Elastase and Clostridium Collagenases
Publikation
Konstantinovic J,
Yahiaoui S,
Alhayek A,
Haupenthal J,
Schönauer E,
Andreas A,
Kany A,
Müller R,
Koehnke J,
Berger F,
Bischoff M,
Hartmann R,
Brandstetter H,
Hirsch A
(2020)
J. Med. Chem., 63, 15, 8359-8368, 10.1021/acs.jmedchem.0c00584
J. Med. Chem., 63, 15, 8359-8368, 10.1021/acs.jmedchem.0c00584
Discovery of the first small-molecule CsrA-RNA interaction inhibitors using biophysical screening technologies
Publikation
Maurer C,
Fruth M,
Empting M,
Avrutina O,
Hossmann J,
Nadmid S,
Gorges J,
Herrmann J,
Kazmaier U,
Dersch P,
Muller R,
Hartmann R
(2016)
Future medicinal chemistry, 8, 9, 931-47, 10.4155/fmc-2016-0033, 27253623
Future medicinal chemistry, 8, 9, 931-47, 10.4155/fmc-2016-0033, 27253623
Adaptation of a Bacterial Multidrug Resistance System Revealed by the Structure and Function of AlbA
Publikation
Sikandar A,
Cirnski K,
Testolin G,
Volz C,
Brönstrup M,
Kalinina O,
Müller R,
Koehnke J
(2018)
J. Am. Chem. Soc., 140, 48, 16641-16649, 10.1021/jacs.8b08895, 30422653
J. Am. Chem. Soc., 140, 48, 16641-16649, 10.1021/jacs.8b08895, 30422653
Evolution of novel antibiotic Scaffolds targeting the nucleic acid machineries RNA polymerase, DNA gyrase, and topoisomerase IV
Publikation
Elgaher W
(2016)
Thesis, 10.22028/D291-23193
Thesis, 10.22028/D291-23193
3D bioprinting ofE. coliMG1655 biofilms on human lung epithelial cells for building complexin vitroinfection models
Publikation
Aliyazdi S,
Frisch S,
Hidalgo A,
Frank N,
Krug D,
Müller R,
Schaefer U,
Vogt T,
Loretz B,
Lehr C
(2023)
Biofabrication, 15, 3, 10.1088/1758-5090/acd95e, 37236174
Biofabrication, 15, 3, 10.1088/1758-5090/acd95e, 37236174
Korrektur der absoluten Konfiguration von Chelocardin und Amidochelocardin
Publikation
Sikandar A,
Popoff A,
Jumde R,
Mándi A,
Kaur A,
Elgaher W,
Rosenberger L,
Hüttel S,
Jansen R,
Hunter M,
Köhnke J,
Hirsch A,
Kurtán T,
Müller R
(2023)
Angewandte Chemie (Weinheim an der Bergstrasse, Germany), 135, 40, 10.1002/ange.202306437
Angewandte Chemie (Weinheim an der Bergstrasse, Germany), 135, 40, 10.1002/ange.202306437
Bacterial RNAP Inhibitors: Synthesis and Evaluation of Prodrugs of Aryl‐ureidothiophene‐carboxylic acids
Publikation
Ruthenbeck A,
Elgaher W,
Haupenthal J,
Hartmann R,
Meier C
(2017)
ChemistrySelect, 2, 35, 11899-11905, 10.1002/slct.201702574
ChemistrySelect, 2, 35, 11899-11905, 10.1002/slct.201702574
Crystobactamides
Publikation
Sascha Baumann,
Jennifer Herrmann,
Kathrin Mohr,
Heinrich Steinmetz,
Klaus Gerth,
Ritesh Raju,
Rolf Müller,
Rolf W. Hartmann,
Mostafa Hamed,
Walid A. M. Elgaher,
Maria Moreno,
Franziska Gille,
Liang Liang Wang,
Andreas Kirschning,
Stephan Huettel
(2022)
Patent, C07C237/42; C07C237/44; C07K5/065; C07K7/06; C12N15/52; C12P13/02; A61K38/00, US11225503B2
Patent, C07C237/42; C07C237/44; C07K5/065; C07K7/06; C12N15/52; C12P13/02; A61K38/00, US11225503B2