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Towards click bioconjugations on cube-octameric silsesquioxane scaffolds
Publikation
Fabritz S,
Heyl D,
Bagutski V,
Empting M,
Rikowski E,
Frauendorf H,
Balog I,
Fessner W,
Schneider J,
Avrutina O,
Kolmar H
(2010)
Org. Biomol. Chem., 8, 9, 2212-8, 10.1039/b923393h, 20401398
Org. Biomol. Chem., 8, 9, 2212-8, 10.1039/b923393h, 20401398
Application of copper(I) catalyzed azide-alkyne 3+2 cycloaddition to the synthesis of template-assembled multivalent peptide conjugates
Publikation
Avrutina O,
Empting M,
Fabritz S,
Daneschdar M,
Frauendorf H,
Diederichsen U,
Kolmar H
(2009)
Org. Biomol. Chem., 7, 20, 4177-85, 10.1039/b908261a, 19795056
Org. Biomol. Chem., 7, 20, 4177-85, 10.1039/b908261a, 19795056
SYNTHESIS, ANTI-BRONCHOCONSTRICTIVE, AND ANTIBACTERIAL ACTIVITIES OF SOME NEW 8- SUBSTITUTED-1,3-DIMETHYLXANTHINE DERIVATIVES
Publikation
Elgaher W,
Hayallah A,
Salem O,
Abdel Alim A
(2009)
Bulletin of Pharmaceutical Sciences. Assiut, 32, 1, 153-187, 10.21608/BFSA.2009.63355
Bulletin of Pharmaceutical Sciences. Assiut, 32, 1, 153-187, 10.21608/BFSA.2009.63355
Bioconjugates to specifically render inhibitors water-soluble
Publikation
Hirsch A,
Diederich F,
Antonietti M,
Börner H
(2009)
Soft Matter, 6, 1, 88-91, 10.1039/B915928B
Soft Matter, 6, 1, 88-91, 10.1039/B915928B
Inhibitors of the kinase IspE: structure-activity relationships and co-crystal structure analysis
Publikation
Hirsch A,
Alphey M,
Lauw S,
Seet M,
Barandun L,
Eisenreich W,
Rohdich F,
Hunter W,
Bacher A,
Diederich F
(2008)
Organic & biomolecular chemistry, 6, 15, 2719-30, 10.1039/b804375b, 18633530
Organic & biomolecular chemistry, 6, 15, 2719-30, 10.1039/b804375b, 18633530
Synthesis and characterization of cytidine derivatives that inhibit the kinase IspE of the non-mevalonate pathway for isoprenoid biosynthesis
Publikation
Crane C,
Hirsch A,
Alphey M,
Sgraja T,
Lauw S,
Illarionova V,
Rohdich F,
Eisenreich W,
Hunter W,
Bacher A,
Diederich F
(2008)
ChemMedChem, 3, 1, 91-101, 10.1002/cmdc.200700208, 18033714
ChemMedChem, 3, 1, 91-101, 10.1002/cmdc.200700208, 18033714
Phosphate recognition in structural biology
Publikation
Hirsch A,
Fischer F,
Diederich F
(2007)
Angewandte Chemie (International ed. in English), 46, 3, 338-52, 10.1002/anie.200603420, 17154432
Angewandte Chemie (International ed. in English), 46, 3, 338-52, 10.1002/anie.200603420, 17154432
Nonphosphate inhibitors of IspE protein, a kinase in the non-mevalonate pathway for isoprenoid biosynthesis and a potential target for antimalarial therapy
Publikation
Hirsch A,
Lauw S,
Gersbach P,
Schweizer W,
Rohdich F,
Eisenreich W,
Bacher A,
Diederich F
(2007)
ChemMedChem, 2, 6, 806-10, 10.1002/cmdc.200700014, 17361977
ChemMedChem, 2, 6, 806-10, 10.1002/cmdc.200700014, 17361977
Double conjugate addition of dithiols to propargylic carbonyl systems to generate protected 1,3-dicarbonyl compounds
Publikation
Sneddon H,
van den Heuvel A,
Hirsch A,
Booth R,
Shaw D,
Gaunt M,
Ley S
(2006)
The Journal of organic chemistry, 71, 7, 2715-25, 10.1021/jo052514s, 16555825
The Journal of organic chemistry, 71, 7, 2715-25, 10.1021/jo052514s, 16555825
pH-Responsive Dynaplexes as Potent Apoptosis Inductors by Intracellular Delivery of Survivin siRNA
Publikation
Liu Y,
Ashmawy S,
Latta L,
Weiss A,
Kiefer A,
Nasr S,
Loretz B,
Hirsch A,
Lee S,
Lehr C
(2023)
Biomacromolecules, 24, 8, 3742-3754, 10.1021/acs.biomac.3c00424, 37523746
Biomacromolecules, 24, 8, 3742-3754, 10.1021/acs.biomac.3c00424, 37523746