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Tracheal brush cells release acetylcholine in response to bitter tastants for paracrine and autocrine signaling
Publikation
Hollenhorst M,
Jurastow I,
Nandigama R,
Appenzeller S,
Li L,
Vogel J,
Wiederhold S,
Althaus M,
Empting M,
Altmüller J,
Hirsch A,
Flockerzi V,
Canning B,
Saliba A,
Krasteva-Christ G
(2020)
FASEB j., 34, 1, 316-332, 10.1096/fj.201901314RR
FASEB j., 34, 1, 316-332, 10.1096/fj.201901314RR
(2S,5R)-2-Isopropyl-5-methylcyclohexanone Hydrazones
Publikation
Nesterkina M,
Barbalat D,
Zheltvay I,
Rakipov I,
Atakay M,
Salih B,
Kravchenko I
(2019)
Molbank, 2019, 2, 10.3390/M1062
Molbank, 2019, 2, 10.3390/M1062
Anti-inflammatory and analgesic activity of ointment based on dense ginger extract (Zingiber officinale)
Publikation
Kravchenko I,
Eberle L,
Nesterkina M,
Kobernik A
(2019)
J Herbmed Pharmacol, 8, 2, 126-132, 10.15171/jhp.2019.20
J Herbmed Pharmacol, 8, 2, 126-132, 10.15171/jhp.2019.20
Rational Adaptation of L3MBTL1 Inhibitors to Create Small-Molecule Cbx7 Antagonists
Publikation
Simhadri C,
Daze K,
Douglas S,
Milosevich N,
Monjas L,
Dev A,
Brown T,
Hirsch A,
Wulff J,
Hof F
(2019)
ChemMedChem, 14, 15, 1444-1456, 10.1002/cmdc.201900021, 31254321
ChemMedChem, 14, 15, 1444-1456, 10.1002/cmdc.201900021, 31254321
Fragment-Based Discovery of a Qualified Hit Targeting the Latency-Associated Nuclear Antigen of the Oncogenic Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8
Publikation
Kirsch P,
Jakob V,
Oberhausen K,
Stein S,
Cucarro I,
Schulz T,
Empting M
(2019)
Journal of medicinal chemistry, 62, 8, 3924-3939, 10.1021/acs.jmedchem.8b01827, 30888817
Journal of medicinal chemistry, 62, 8, 3924-3939, 10.1021/acs.jmedchem.8b01827, 30888817
From Dyrk1A inhibitors to a novel class of antiviral agents: Targeting Enterovirus EV-A71 with 2-aryl-substituted thiophene scaffolds
Publikation
Keddis P,
My Tu T,
Scherer H,
Kany A,
Hafez D,
Darwish S,
Abadi A,
Hirsch A,
Engel M,
Hamed M,
Horng J,
Abdel-Halim M
(2025)
Eur. J. Med. Chem., 287, 10.1016/j.ejmech.2025.117348, 39947051
Eur. J. Med. Chem., 287, 10.1016/j.ejmech.2025.117348, 39947051
Apo structure of Mycobacterium tuberculosis 1-deoxy-d-xylulose 5-phosphate synthase DXPS: Dynamics and implications for inhibitor design
Publikation
Gawriljuk V,
Alhayek A,
Hirsch A,
Groves M
(2025)
Biochemical and Biophysical Research Communications, 747, 10.1016/j.bbrc.2024.151246
Biochemical and Biophysical Research Communications, 747, 10.1016/j.bbrc.2024.151246
Direct monitoring of intracellular polymer degradation via BODIPY dynamic dequenching
Publikation
Bassil J,
Kamal M,
Gabelmann A,
Christoulaki A,
Koch M,
Hamed M,
Loretz B,
Gallei M,
Buhler E,
Lehr C,
Hirsch A,
Lee S
(2025)
Mater. Des., 256, 10.1016/j.matdes.2025.114240
Mater. Des., 256, 10.1016/j.matdes.2025.114240
Targeting IspD for Anti-infective and Herbicide Development: Exploring Its Role, Mechanism, and Structural Insights
Publikation
Willocx D,
Diamanti E,
Hirsch A
(2025)
Journal of medicinal chemistry, 10.1021/acs.jmedchem.4c01146, 39749898
Journal of medicinal chemistry, 10.1021/acs.jmedchem.4c01146, 39749898
Lignin-derived guaiacols as platform chemicals for the modular synthesis of 1,2,3,4-tetrahydroquinolines and benzomorpholines
Publikation
Castillo-Garcia A,
Haupenthal J,
Hirsch A,
Barta K
(2025)
RSC sustainability, 3, 9, 4039-4048, 10.1039/d5su00151j, 40686926
RSC sustainability, 3, 9, 4039-4048, 10.1039/d5su00151j, 40686926