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Cryo-EM structure of 1-deoxy-D-xylulose 5-phosphate synthase DXPS from Plasmodium falciparum reveals a distinct N-terminal domain
Publikation
Gawriljuk V,
Godoy A,
Oerlemans R,
Welker L,
Hirsch A,
Groves M
(2024)
Nat. Commun., 15, 1, 10.1038/s41467-024-50671-9, 39103329
Nat. Commun., 15, 1, 10.1038/s41467-024-50671-9, 39103329
Fragment Discovery by X-Ray Crystallographic Screening Targeting the CTP Binding Site of Pseudomonas Aeruginosa IspD
Publikation
Willocx D,
D'Auria L,
Walsh D,
Scherer H,
Alhayek A,
Hamed M,
Borel F,
Diamanti E,
Hirsch A
(2024)
Angew. Chem., Int. Ed. Engl., 10.1002/anie.202414615, 39676054
Angew. Chem., Int. Ed. Engl., 10.1002/anie.202414615, 39676054
Target-Directed Dynamic Combinatorial Chemistry Affords Binders of Mycobacterium tuberculosis IspE
Publikation
Braun-Cornejo M,
Ornago C,
Sonawane V,
Haupenthal J,
Kany A,
Diamanti E,
Jézéquel G,
Reiling N,
Blankenfeldt W,
Maas P,
Hirsch A
(2024)
ACS omega, 10.1021/acsomega.4c05537
ACS omega, 10.1021/acsomega.4c05537
Synthesis and Anticonvulsant Activity of Menthyl γ-Aminobutyrate
Publikation
Nesterkina M,
Kravchenko I
(2016)
Chem Nat Compd, 52, 2, 237-239, 10.1007/s10600-016-1604-9
Chem Nat Compd, 52, 2, 237-239, 10.1007/s10600-016-1604-9
Synthesis and Pharmacological Properties of Novel Esters Based on Monocyclic Terpenes and GABA
Publikation
Nesterkina M,
Kravchenko I
(2016)
Pharmaceuticals (Basel, Switzerland), 9, 2, 10.3390/ph9020032, 27304960
Pharmaceuticals (Basel, Switzerland), 9, 2, 10.3390/ph9020032, 27304960
Analgesic Activity of Novel GABA Esters after Transdermal Delivery
Publikation
Nesterkina M,
Kravchenko I
(2016)
Nat. Prod. Commun., 11, 10, 10.1177/1934578X1601101001
Nat. Prod. Commun., 11, 10, 10.1177/1934578X1601101001
Single-domain antibodies for biomedical applications
Publikation
Krah S,
Schröter C,
Zielonka S,
Empting M,
Valldorf B,
Kolmar H
(2016)
Immunopharmacol. Immunotoxicol., 38, 1, 21-8, 10.3109/08923973.2015.1102934, 26551147
Immunopharmacol. Immunotoxicol., 38, 1, 21-8, 10.3109/08923973.2015.1102934, 26551147
Synthesis and Anticonvulsant Activity of New Calix[4]Arene Derivatives Containing Gamma-Aminobutyric Acid Moieties
Publikation
Nesterkina M,
Alekseeva E,
Kravchenko I
(2016)
Pharm Chem J, 49, 12, 825-829, 10.1007/s11094-016-1380-7
Pharm Chem J, 49, 12, 825-829, 10.1007/s11094-016-1380-7
Proteoid Dynamers with Tunable Properties
Publikation
Liu Y,
Stuart M,
Buhler E,
Lehn J,
Hirsch A
(2016)
, 10.1002/ADFM.201601612
, 10.1002/ADFM.201601612
Towards the evaluation in an animal disease model: Fluorinated 17β-HSD1 inhibitors showing strong activity towards both the human and the rat enzyme
Publikation
Abdelsamie A,
Bey E,
Gargano E,
van Koppen C,
Empting M,
Frotscher M
(2015)
European journal of medicinal chemistry, 103, 56-68, 10.1016/j.ejmech.2015.08.030, 26322835
European journal of medicinal chemistry, 103, 56-68, 10.1016/j.ejmech.2015.08.030, 26322835