![[Translate to Deutsch:]](/fileadmin/HIPS/__processed__/3/9/csm_HIPS_50243_47cfe3711c.jpg "[Translate to Deutsch:]")
Suche
Synthesis and Structure of a Coordination Polymer of Ni(II) with 2-(4-Bromophenoxy)acetohydrazide
Publikation
Martsynko ?,
Nesterkina M,
Finik ?,
Tsymbaliuk K,
Dyakonenko V,
Shishkina S,
Kravchenko I
(2024)
Molbank, 2024, 2, 10.3390/M1819
Molbank, 2024, 2, 10.3390/M1819
Target repurposing unravels avermectins and derivatives as novel antibiotics inhibiting energy-coupling factor transporters (ECFTs)
Publikation
Haupenthal J,
Rafehi M,
Kany A,
Lespine A,
Stefan K,
Hirsch* A,
Stefan* S
(2024)
Arch. Pharm., 10.1002/ardp.202400267, 38896404
Arch. Pharm., 10.1002/ardp.202400267, 38896404
Not Every Hit-Identification Technique Works on 1-Deoxy-d-Xylulose 5-Phosphate Synthase (DXPS): Making the Most of a Virtual Screening Campaign
Publikation
Johannsen S,
Gierse R,
Olshanova A,
Smerznak E,
Laggner C,
Eschweiler L,
Adeli Z,
Hamid R,
Alhayek A,
Reiling N,
Haupenthal J,
Hirsch A
(2023)
ChemMedChem, 10.1002/cmdc.202200590, 36896721
ChemMedChem, 10.1002/cmdc.202200590, 36896721
Exploring the Translational Gap of a Novel Class of Escherichia coli IspE Inhibitors
Publikation
Ropponen H,
Diamanti E,
Johannsen S,
Illarionov B,
Hamid R,
Jaki M,
Sass P,
Fischer M,
Haupenthal J,
Hirsch A
(2023)
ChemMedChem, 10.1002/cmdc.202300346, 37718320
ChemMedChem, 10.1002/cmdc.202300346, 37718320
From Dyrk1A inhibitors to a novel class of antiviral agents: Targeting Enterovirus EV-A71 with 2-aryl-substituted thiophene scaffolds
Publikation
Keddis P,
My Tu T,
Scherer H,
Kany A,
Hafez D,
Darwish S,
Abadi A,
Hirsch A,
Engel M,
Hamed M,
Horng J,
Abdel-Halim M
(2025)
Eur. J. Med. Chem., 287, 10.1016/j.ejmech.2025.117348, 39947051
Eur. J. Med. Chem., 287, 10.1016/j.ejmech.2025.117348, 39947051
Apo structure of Mycobacterium tuberculosis 1-deoxy-d-xylulose 5-phosphate synthase DXPS: Dynamics and implications for inhibitor design
Publikation
Gawriljuk V,
Alhayek A,
Hirsch A,
Groves M
(2025)
Biochemical and Biophysical Research Communications, 747, 10.1016/j.bbrc.2024.151246
Biochemical and Biophysical Research Communications, 747, 10.1016/j.bbrc.2024.151246
Targeting IspD for Anti-infective and Herbicide Development: Exploring Its Role, Mechanism, and Structural Insights
Publikation
Willocx D,
Diamanti E,
Hirsch A
(2025)
Journal of medicinal chemistry, 10.1021/acs.jmedchem.4c01146, 39749898
Journal of medicinal chemistry, 10.1021/acs.jmedchem.4c01146, 39749898
Development of Fragment-Based Inhibitors of the Bacterial Deacetylase LpxC with Low Nanomolar Activity
Publikation
Mielniczuk S,
Hoff K,
Baselious F,
Li Y,
Haupenthal J,
Kany A,
Riedner M,
Rohde H,
Rox K,
Hirsch A,
Krimm I,
Sippl W,
Holl R
(2024)
Journal of medicinal chemistry, 67, 19, 17363-17391, 10.1021/acs.jmedchem.4c01262, 39303295
Journal of medicinal chemistry, 67, 19, 17363-17391, 10.1021/acs.jmedchem.4c01262, 39303295
Novel 6-hydroxybenzothiazol-2-carboxamides as potent and selective monoamine oxidase B inhibitors endowed with neuroprotective activity
Publikation
Al-Saad O,
Gabr M,
Darwish S,
Rullo M,
Pisani L,
Miniero D,
Liuzzi G,
Kany A,
Hirsch A,
Abadi A,
Engel M,
Catto M,
Abdel-Halim M
(2024)
European journal of medicinal chemistry, 10.1016/j.ejmech.2024.116266
European journal of medicinal chemistry, 10.1016/j.ejmech.2024.116266
Two natural compounds as potential inhibitors against the Helicobacter pylori and Acinetobacter baumannii IspD enzymes
Publikation
Chen X,
Zhao H,
Wang C,
Hamed M,
Shang Q,
Yang Y,
Diao X,
Sun X,
Hu W,
Jiang X,
Zhang Y,
Hirsch A,
Wu D,
Zhuang J
(2024)
Int. J. Antimicrob. Agents, 63, 5, 10.1016/j.ijantimicag.2024.107160, 38537721
Int. J. Antimicrob. Agents, 63, 5, 10.1016/j.ijantimicag.2024.107160, 38537721