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Gesucht nach "drug". Zeige Ergebnisse 621 bis 630 von 699.

Engineering a Constrained Peptidic Scaffold towards Potent and Selective Furin Inhibitors

Publikation
Fittler H, Depp A, Avrutina O, Dahms S, Than M, Empting M, Kolmar H (2015)
Chembiochem : a European journal of chemical biology, 16, 17, 2441-4, 10.1002/cbic.201500447, 26426719

Catechol-based substrates of chalcone synthase as a scaffold for novel inhibitors of PqsD

Publikation
Allegretta G, Weidel E, Empting M, Hartmann R (2015)
European journal of medicinal chemistry, 90, 351-9, 10.1016/j.ejmech.2014.11.055, 25437621

Harnessing dynamic combinatorial chemistry in the search for new ligands for protein targets

Publikation
Monjas L, Hirsch A (2015)
Future medicinal chemistry, 7, 16, 2095-8, 10.4155/fmc.15.146, 26510895

Structure-Based Optimization of Inhibitors of the Aspartic Protease Endothiapepsin

Publikation
Hartman A, Mondal M, Radeva N, Klebe G, Hirsch A (2015)
International journal of molecular sciences, 16, 8, 19184-94, 10.3390/ijms160819184, 26287174

Dynamic combinatorial chemistry: a tool to facilitate the identification of inhibitors for protein targets

Publikation
Mondal M, Hirsch A (2015)
Chemical Society reviews, 44, 8, 2455-88, 10.1039/c4cs00493k, 25706945

De novo fragment-based design of inhibitors of DXS guided by spin-diffusion-based NMR spectroscopy

Publikation
Masini T, Pilger J, Kroezen B, Illarionov B, Lottmann P, Fischer M, Griesinger C, Hirsch A (2014)
Chem. Sci., 5, 9, 3543-3551, 10.1039/C4SC00588K

A doubly hermaphroditic chiral crown ether

Publikation
Hirsch A, Sirlin C, Harrowfield J, Lehn J (2014)
, 10.1039/C4CE00879K

Composing compound libraries for hit discovery--rationality-driven preselection or random choice by structural diversity?

Publikation
Weidel E, Negri M, Empting M, Hinsberger S, Hartmann R (2014)
Future medicinal chemistry, 6, 18, 2057-72, 10.4155/fmc.14.142, 25531968

Benzamidobenzoic acids as potent PqsD inhibitors for the treatment of Pseudomonas aeruginosa infections

Publikation
Hinsberger S, Jong J, Groh M, Haupenthal J, Hartmann R (2014)
European journal of medicinal chemistry, 76, 343-51, 10.1016/j.ejmech.2014.02.014, 24589489

Synthesis, Physicochemical Properties, and Anticonvulsant Activity of the Gaba Complex with a Calix[4]Arene derivative

Publikation
Nesterkina M, Alekseeva E, Kravchenko I (2014)
Pharm Chem J, 48, 2, 82-84, 10.1007/s11094-014-1052-4