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Discovery of Small-Molecule Stabilizers of 14-3-3 Protein-Protein Interactions via Dynamic Combinatorial Chemistry
Publikation
Hartman A,
Elgaher W,
Hertrich N,
Andrei S,
Ottmann C,
Hirsch A
(2020)
ACS medicinal chemistry letters, 11, 5, 1041-1046, 10.1021/acsmedchemlett.9b00541, 32435423
ACS medicinal chemistry letters, 11, 5, 1041-1046, 10.1021/acsmedchemlett.9b00541, 32435423
QSAR models for analgesic activity prediction of terpenes and their derivatives
Publikation
Nesterkina M,
Ognichenko L,
Shyrykalova A,
Kravchenko I,
Kuz’min V
(2020)
Struct Chem, 31, 3, 947-954, 10.1007/s11224-019-01479-7
Struct Chem, 31, 3, 947-954, 10.1007/s11224-019-01479-7
9,10-Anthraquinone Dithiocarbamates as Potential Pharmaceutical Substances with Pleiotropic Actions: Computerized Prediction of Biological Activity and Experimental Validation
Publikation
Stasevich M,
Zvarich V,
Novikov V,
Zagorodnyaya S,
Povnitsa O,
Chaika M,
Nesterkina M,
Kravchenko I,
Druzhilovskii D,
Poroikov V
(2020)
Pharm Chem J, 53, 10, 905-913, 10.1007/s11094-020-02098-x
Pharm Chem J, 53, 10, 905-913, 10.1007/s11094-020-02098-x
Phytochemical analysis and anti-inflammatory activity of Cladophora aegagropila extract
Publikation
Aleksandrova A,
Nesterkina M,
Gvozdii S,
Kravchenko I
(2020)
J Herbmed Pharmacol, 9, 1, 81-85, 10.15171/jhp.2020.12
J Herbmed Pharmacol, 9, 1, 81-85, 10.15171/jhp.2020.12
Potential Dental Biofilm Inhibitors: Dynamic Combinatorial Chemistry Affords Sugar-Based Molecules that Target Bacterial Glucosyltransferase
Publikation
Hartman A,
Jumde V,
Elgaher W,
Te Poele E,
Dijkhuizen L,
Hirsch A
(2020)
ChemMedChem, 10.1002/cmdc.202000222, 32542998
ChemMedChem, 10.1002/cmdc.202000222, 32542998
Optimized Inhibitors of MDM2 via an Attempted Protein‐Templated Reductive Amination
Publikation
Vlag R,
Yagiz Unver M,
Felicetti T,
Twarda-Clapa A,
Kassim F,
Ermis C,
Neochoritis C,
Musielak B,
Labuzek B,
Dömling A,
Holak T,
Hirsch A
(2020)
ChemMedChem, 15, 4, 370-375, 10.1002/cmdc.201900574
ChemMedChem, 15, 4, 370-375, 10.1002/cmdc.201900574
2-Propyl-N′-[1,7,7-trimethylbicyclo[2.2.1]hept-2-ylidene]pentanehydrazide
Publikation
Nesterkina M,
Barbalat D,
Rakipov I,
Kravchenko I
(2020)
Molbank, 2020, 4, 10.3390/M1164
Molbank, 2020, 4, 10.3390/M1164
Protein‐Templated Hit Identification through an Ugi Four‐Component Reaction
Publikation
Federica Mancini,
M. Yagiz Unver,
Walid A. M. Elgaher,
Varsha R. Jumde,
Alaa Alhayek,
Peer Lukat,
Jennifer Herrmann,
Martin D. Witte,
Matthias Köck,
Wulf Blankenfeldt,
Rolf Müller,
Hirsch A
(2020)
Chemistry – A European Journal, 26, 64, 10.1002/chem.202086462
Chemistry – A European Journal, 26, 64, 10.1002/chem.202086462
Design, synthesis and pharmacological profile of (−)-verbenone hydrazones
Publikation
Nesterkina M,
Barbalat D,
Kravchenko I
(2020)
Open Chemistry, 18, 1, 943-950, 10.1515/chem-2020-0103
Open Chemistry, 18, 1, 943-950, 10.1515/chem-2020-0103
7-Hydroxycoumarins are Affinity-based Fluorescent Probes for Competitive Binding Studies of Macrophage Migration Inhibitory Factor
Publikation
Xiao Z,
Chen D,
Song S,
van der Vlag R,
van der Wouden P,
van Merkerk R,
Cool R,
Hirsch A,
Melgert B,
Quax W,
Poelarends G,
Dekker F
(2020)
Journal of medicinal chemistry, 10.1021/acs.jmedchem.0c01160, 32940040
Journal of medicinal chemistry, 10.1021/acs.jmedchem.0c01160, 32940040