![[Translate to Deutsch:]](/fileadmin/HIPS/__processed__/3/9/csm_HIPS_50243_47cfe3711c.jpg "[Translate to Deutsch:]")
Suche
Respiratory Syncytial Virus Two-Step Infection Screen Reveals Inhibitors of Early and Late Life Cycle Stages
Publikation
Sake S,
Kosch C,
Blockus S,
Haid S,
Gunesch A,
Zhang X,
Friesland M,
Trummer S,
Grethe C,
Kühnel A,
Rückert J,
Duprex W,
Huang J,
Rameix-Welti M,
Empting M,
Fischer N,
Hirsch A,
Schulz T,
Pietschmann T
(2022)
Antimicrobial agents and chemotherapy, 10.1128/aac.01032-22, 36346232
Antimicrobial agents and chemotherapy, 10.1128/aac.01032-22, 36346232
Identification of RAD51-BRCA2 Inhibitors Using N-Acylhydrazone-Based Dynamic Combinatorial Chemistry
Publikation
Bagnolini G,
Balboni B,
Schipani F,
Gioia D,
Veronesi M,
Franco F,
Kaya C,
Jumde R,
Ortega J,
Girotto S,
Hirsch A,
Roberti M,
Cavalli A
(2022)
ACS Med. Chem. Lett., 13, 8, 1262-1269, 10.1021/acsmedchemlett.2c00063, 35978685
ACS Med. Chem. Lett., 13, 8, 1262-1269, 10.1021/acsmedchemlett.2c00063, 35978685
Genotoxic and mutational potential of monocyclic terpenoids (carvacrol, carvone and thymol) in Drosophila melanogaster
Publikation
Nesterkina M,
Bilokon S,
Alieksieieva T,
Kravchenko I,
Hirsch A
(2023)
Toxicol. Rep., 10, 10.1016/j.toxrep.2023.02.009
Toxicol. Rep., 10, 10.1016/j.toxrep.2023.02.009
Selective Activation of TRPC6 Ion Channel by Metallated Type-B Polyprenylated Polycyclic Acylphloroglucinols
Publikation
Peslalz P,
Kraus F,
Izzo F,
Bleisch A,
El Hamdaoui Y,
Schulz I,
Kany A,
Hirsch A,
Friedland K,
Plietker B
(2023)
Manuscript, 10.26434/chemrxiv-2023-6w94r
Manuscript, 10.26434/chemrxiv-2023-6w94r
Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle
Publikation
Hamed M,
Abdelsamie A,
Rox K,
Schütz C,
Kany A,
Röhrig T,
Schmelz S,
Blankenfeldt W,
Arce-Rodriguez A,
Borrero-de Acuña J,
Jahn D,
Rademacher J,
Ringshausen F,
Cramer N,
Tümmler B,
Hirsch A,
Hartmann R,
Empting M
(2023)
Adv. Sci., Online, 10.1002/advs.202204443
Adv. Sci., Online, 10.1002/advs.202204443
Design of thiamine analogues for inhibition of thiamine diphosphate (ThDP)-dependent enzymes: Systematic investigation through Scaffold-Hopping and C2-Functionalisation
Publikation
Chan A,
Ho T,
Irfan R,
Hamid R,
Rudge E,
Iqbal A,
Turner A,
Hirsch A.,
Leeper F
(2023)
Bioorganic chemistry, 138, 10.1016/j.bioorg.2023.106602
Bioorganic chemistry, 138, 10.1016/j.bioorg.2023.106602
1-deoxy-D-xylulose-5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding
Publikation
Hamid R,
Adam S,
Lacour A,
Monjas L,
Köhnke J,
Hirsch A
(2023)
The Journal of biological chemistry, 10.1016/j.jbc.2023.105152, 37567475
The Journal of biological chemistry, 10.1016/j.jbc.2023.105152, 37567475
Identification of HuR–RNA Interfering Compounds by Dynamic Combinatorial Chemistry and Fluorescence Polarization
Publikation
Della Volpe S,
Listro R,
Ambrosio F,
Garbagnoli M,
Linciano P,
Rossi D,
Costa G,
Alcaro S,
Vasile F,
Hirsch A,
Collina S
(2023)
ACS Med. Chem. Lett., 10.1021/acsmedchemlett.3c00303
ACS Med. Chem. Lett., 10.1021/acsmedchemlett.3c00303
NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner
Publikation
Waqas F,
Shehata M,
Elgaher W,
Lacour A,
Kurmasheva N,
Begnini F,
Kiib A,
Dahlmann J,
Chen C,
Pavlou A,
Poulsen T,
Merkert S,
Martin U,
Olmer R,
Olagnier D,
Hirsch A,
Pleschka S,
Pessler F
(2023)
PLOS Pathogens, 19, 7, 10.1371/journal.ppat.1011506, 37459366
PLOS Pathogens, 19, 7, 10.1371/journal.ppat.1011506, 37459366
Structure of Mycobacterium tuberculosis 1-Deoxy-D-Xylulose 5-Phosphate Synthase in Complex with Butylacetylphosphonate
Publikation
Gawriljuk V,
Oerlemans R,
Gierse R,
Jotwani R,
Hirsch A,
Groves M
(2023)
Crystals, 13, 5, 10.3390/cryst13050737
Crystals, 13, 5, 10.3390/cryst13050737