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Behavioral and electrophysiological responses of the male medfly, Ceratitis capitata, to thymol and carvacrol ethers
Publikation
Tabanca N,
Cloonan K,
Nesterkina M,
Gill M,
Montgomery W,
Kravchenko I,
Kendra P
(2024)
Pest management science, 10.1002/ps.8324, 39096116
Pest management science, 10.1002/ps.8324, 39096116
Evaluation of ketoclomazone and its analogues as inhibitors of 1-deoxy-d-xylulose 5-phosphate synthases and other thiamine diphosphate (ThDP)-dependent enzymes
Publikation
Chan A,
Ho T,
Fathoni I,
Hamid R,
Hirsch A,
Saliba K,
Leeper F
(2024)
RSC Med. Chem., 15, 5, 1773-1781, 10.1039/D4MD00083H, 38784473
RSC Med. Chem., 15, 5, 1773-1781, 10.1039/D4MD00083H, 38784473
Identification of DksA as a novel pro-inflammatory mediator of Pseudomonas aeruginosa under conditions mimicking chronic cystic fibrosis lung infection
Publikation
Wauters M,
Bollé L,
Meester G,
van den Bossche S,
Grassi L,
van Haver D,
Dufour S,
Devos S,
Impens F,
van Braeckel E,
Hirsch A,
Whiteley M,
Saelens X,
Crabbé A
(2026)
Virulence, 17, 1, 10.1080/21505594.2026.2670050, 42117785
Virulence, 17, 1, 10.1080/21505594.2026.2670050, 42117785
Multiparameter Optimization of Pseudomonas aeruginosa Elastase Inhibitors for Systemic Administration
Publikation
Abdelsamie A,
Konstantinovic J,
Kany A,
Schütz C,
Kolling D,
Speicher S,
Klein A,
Shafiei R,
Bouté M,
Mundry K,
Park Y,
Loretz B,
Müller R,
Sallenave J,
Lehr C,
Koehnke J,
Rox K,
Haupenthal J,
Hirsch A
(2026)
J. Med. Chem., 69, 4, 4160-4186, 10.1021/acs.jmedchem.5c02788, 41642952
J. Med. Chem., 69, 4, 4160-4186, 10.1021/acs.jmedchem.5c02788, 41642952
An investigation of phosphinamides as a functional group for medicinal chemistry
Publikation
Meurillon V,
Blanchart P,
Ullah V,
Chan D,
Perry M
(2026)
Med Chem Res, 35, 1, 118-134, 10.1007/s00044-025-03498-y
Med Chem Res, 35, 1, 118-134, 10.1007/s00044-025-03498-y
Hit-to-Lead Optimization of Energy-Coupling Factor (ECF) Transporter Inhibitors as Novel Antibiotic
Publikation
Exapicheidou I,
Tsarenko A,
Zeller L,
Ibrahim H,
Baumann C,
Shams A,
Hoffmann P,
Li Y,
Kany A,
Hermann J,
Slotboom D,
Müller R,
Volkamer A,
Hamed M,
Diamanti E,
Hirsch A
(2026)
J. Med. Chem., 10.1021/acs.jmedchem.5c02721, 42249838
J. Med. Chem., 10.1021/acs.jmedchem.5c02721, 42249838
Cytochrome P450-Mediated Metabolism of Antimycobacterial Nα-Aroyl-N-aryl-phenylalanine Amides
Publikation
Doering J,
Meerz E,
Seidel R,
Lang M,
Kany A,
Auriola S,
Juvonen R,
Raunio H,
Goddard R,
Zimmerman M,
Dartois V,
Hirsch A,
Dick T,
Richter A
(2026)
ACS Infect. Dis., 10.1021/acsinfecdis.6c00100, 42227659
ACS Infect. Dis., 10.1021/acsinfecdis.6c00100, 42227659
Identification of Natural-Product Inhibitors of the 2 C -Methyl- d -erythritol 4-Phosphate Pathway
Publikation
Diamanti E,
Alhayek A,
Lacour A,
Shahrour M,
Willocx D,
Illarionov B,
Fischer M,
Stadler M,
Reiling N,
Herrmann J,
Müller R,
Hirsch A
(2026)
ACS Med. Chem. Lett., 10.1021/acsmedchemlett.6c00054
ACS Med. Chem. Lett., 10.1021/acsmedchemlett.6c00054
Design and Optimization of Simplified Inhibitors Targeting E. coli and K. pneumoniae IspE
Publikation
Walsh D,
Hamid R,
Giele T,
Rottmann M,
Hirsch A,
Hamed M,
Reiling N
(2026)
RSC Med. Chem., 10.1039/D5MD00874C
RSC Med. Chem., 10.1039/D5MD00874C
Exploring the Role of Pseudomonas aeruginosa Elastase in Lung Epithelial Barrier Dysfunction: Advancing toward Antivirulence Therapies
Publikation
Shafiei R,
Alhayek A,
Hiller L,
Latta L,
Neu T,
Aljohmani A,
Abdollahibiroun S,
Schönborn E,
Yildiz D,
Schneider-Daum N,
Lehr C,
Haupenthal J,
Hirsch A
(2026)
ACS Infect. Dis., 10.1021/acsinfecdis.5c00915, 41960628
ACS Infect. Dis., 10.1021/acsinfecdis.5c00915, 41960628