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Gesucht nach "drug". Zeige Ergebnisse 571 bis 580 von 699.

Toxic effect and genotoxicity of carvacrol ethers in Drosophila melanogaster

Publikation
Nesterkina M, Bilokon S, Alieksieieva T, Chebotar S, Kravchenko I (2020)
Mutat. Res., 821, 2, 10.1016/j.mrfmmm.2020.111713, 32593030

François Diederich – In Memoriam**

Publikation
Hof F, Hirsch A (2020)
ChemMedChem, 10.1002/cmdc.202000920

BOPC1 Enantiomers Preparation and HuR Interaction Study. From Molecular Modeling to a Curious DEEP-STD NMR Application

Publikation
Della Volpe S, Listro R, Parafioriti M, Di Giacomo M, Rossi D, Ambrosio F, Costa G, Alcaro S, Ortuso F, Hirsch A, Vasile F, Collina S (2020)
ACS medicinal chemistry letters, 11, 5, 883-888, 10.1021/acsmedchemlett.9b00659, 32435400

Rapid Discovery of Aspartyl Protease Inhibitors Using an Anchoring Approach

Publikation
Konstantinidou M, Magari F, Sutanto F, Haupenthal J, Jumde R, Ünver M, Heine A, Camacho C, Hirsch A, Klebe G, Dömling A (2020)
ChemMedChem, 15, 8, 680-684, 10.1002/cmdc.202000024

Overcoming the unexpected functional inversion of a PqsR antagonist in Pseudomonas aeruginosa: an in vivo potent antivirulence agent targeting pqs quorum sensing

Publikation
Lu C, Maurer C, Kirsch B, Steinbach A, Hartmann R (2014)
Angewandte Chemie (International ed. in English), 53, 4, 1109-12, 10.1002/anie.201307547, 24338917

Structure-based design of inhibitors of the aspartic protease endothiapepsin by exploiting dynamic combinatorial chemistry

Publikation
Mondal M, Radeva N, Köster H, Park A, Potamitis C, Zervou M, Klebe G, Hirsch A (2014)
Angewandte Chemie (International ed. in English), 53, 12, 3259-63, 10.1002/anie.201309682, 24532096

Design and synthesis of a library of lead-like 2,4-bisheterocyclic substituted thiophenes as selective Dyrk/Clk inhibitors

Publikation
Schmitt C, Kail D, Mariano M, Empting M, Weber N, Paul T, Hartmann R, Engel M (2014)
PLoS ONE, 9, 3, 10.1371/journal.pone.0087851, 24676346

A natural-product switch for a dynamic protein interface

Publikation
Scheepstra M, Nieto L, Hirsch A, Fuchs S, Leysen S, Lam C, het Panhuis L, van Boeckel C, Wienk H, Boelens R, Ottmann C, Milroy L, Brunsveld L (2014)
Angewandte Chemie (International ed. in English), 53, 25, 6443-8, 10.1002/anie.201403773, 24821627

Inhibition of 17β-HSD1: SAR of bicyclic substituted hydroxyphenylmethanones and discovery of new potent inhibitors with thioether linker

Publikation
Abdelsamie A, Bey E, Hanke N, Empting M, Hartmann R, Frotscher M (2014)
European journal of medicinal chemistry, 82, 394-406, 10.1016/j.ejmech.2014.05.074, 24929290

Theoretical and structural analysis of long C-C bonds in the adducts of polycyanoethylene and anthracene derivatives and their connection to the reversibility of Diels-Alder reactions

Publikation
Hirsch A, Reutenauer P, Le Moignan M, Ulrich S, Boul P, Harrowfield J, Jarowski P, Lehn J (2014)
Chemistry (Weinheim an der Bergstrasse, Germany), 20, 4, 1073-80, 10.1002/chem.201303276, 24339005