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Molecular Biodynamers: Dynamic Covalent Analogues of Biopolymers
Publikation
Liu Y,
Lehn J,
Hirsch A
(2017)
Accounts of chemical research, 50, 2, 376-386, 10.1021/acs.accounts.6b00594
Accounts of chemical research, 50, 2, 376-386, 10.1021/acs.accounts.6b00594
Dynamic Combinatorial Chemistry to Identify Binders of ThiT, an S-Component of the Energy-Coupling Factor Transporter for Thiamine
Publikation
Monjas L,
Swier L,
Setyawati I,
slotboom d,
Hirsch A
(2017)
ChemMedChem, 12, 20, 1693-1696, 10.1002/cmdc.201700440, 28960943
ChemMedChem, 12, 20, 1693-1696, 10.1002/cmdc.201700440, 28960943
Bicyclic enol cyclocarbamates inhibit penicillin-binding proteins
Publikation
Dockerty P,
Edens J,
Tol M,
Morales Angeles D,
Domenech A,
Liu Y,
Hirsch A,
veening j,
Scheffers D,
Witte M
(2017)
Organic & biomolecular chemistry, 15, 4, 894-910, 10.1039/c6ob01664b, 28045164
Organic & biomolecular chemistry, 15, 4, 894-910, 10.1039/c6ob01664b, 28045164
PHARMACOLOGICAL AND PHYSICO-CHEMICAL PROPERTIES OF COMPOSITIONS BASED ON BIOSURFACTANTS AND N-CONTAINING HETEROCYCLIC DERIVATIVES OF 1,4-NAPHTHOQUINONE
Publikation
Polish N,
Nesterkina M,
Karkhut A,
Marintsova N,
Zhurakhivska L,
Volianiuk K,
Pokynbroda T,
Kravchenko I,
Karpenko E
(2022)
J microb biotech food sci, 12, 3, 10.55251/jmbfs.5956
J microb biotech food sci, 12, 3, 10.55251/jmbfs.5956
Structural analysis of 1-deoxy-D-xylulose 5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding
Publikation
Hamid R,
Adam S,
Lacour A,
Gomez L,
Hirsch A
(2022)
bioRxiv, 10.1101/2022.07.04.498669
bioRxiv, 10.1101/2022.07.04.498669
Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism
Publikation
Chen F,
Elgaher W,
Winterhoff M,
Büssow K,
Waqas F,
Graner E,
Pires-Afonso Y,
Casares Perez L,
La Vega L,
Sahini N,
Czichon L,
Zobl W,
Zillinger T,
Shehata M,
Pleschka S,
Bähre H,
Falk C,
Michelucci A,
Schuchardt S,
Blankenfeldt W,
Hirsch A,
Pessler F
(2022)
Nature metabolism, 4, 5, 534-546, 10.1038/s42255-022-00577-x, 35655026
Nature metabolism, 4, 5, 534-546, 10.1038/s42255-022-00577-x, 35655026
Targeting Extracellular Bacterial Proteases for the Development of Novel Antivirulence Agents
Publikation
Kaya C,
Hirsch A
(2022)
Chimia, 76, 5, 10.2533/chimia.2022.402
Chimia, 76, 5, 10.2533/chimia.2022.402
Screening of Natural Products and Small Molecules Uncovers Novel Coronavirus 1a/1b Frameshifting Inhibitors with Antiviral Properties
Publikation
Kibe A,
Elgaher W,
Rand U,
Zimmer M,
Kany A,
Hermann J,
Müller R,
Cicin-Sain L,
Hirsch A,
Caliskan N
(2022)
SSRN Journal, 10.2139/ssrn.4157446
SSRN Journal, 10.2139/ssrn.4157446
Respiratory Syncytial Virus Two-Step Infection Screen Reveals Inhibitors of Early and Late Life Cycle Stages
Publikation
Sake S,
Kosch C,
Blockus S,
Haid S,
Gunesch A,
Zhang X,
Friesland M,
Trummer S,
Grethe C,
Kühnel A,
Rückert J,
Duprex W,
Huang J,
Rameix-Welti M,
Empting M,
Fischer N,
Hirsch A,
Schulz T,
Pietschmann T
(2022)
Antimicrobial agents and chemotherapy, 10.1128/aac.01032-22, 36346232
Antimicrobial agents and chemotherapy, 10.1128/aac.01032-22, 36346232
Identification of RAD51-BRCA2 Inhibitors Using N-Acylhydrazone-Based Dynamic Combinatorial Chemistry
Publikation
Bagnolini G,
Balboni B,
Schipani F,
Gioia D,
Veronesi M,
Franco F,
Kaya C,
Jumde R,
Ortega J,
Girotto S,
Hirsch A,
Roberti M,
Cavalli A
(2022)
ACS Med. Chem. Lett., 13, 8, 1262-1269, 10.1021/acsmedchemlett.2c00063, 35978685
ACS Med. Chem. Lett., 13, 8, 1262-1269, 10.1021/acsmedchemlett.2c00063, 35978685