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Genotoxic and mutational potential of monocyclic terpenoids (carvacrol, carvone and thymol) in Drosophila melanogaster
Publikation
Nesterkina M,
Bilokon S,
Alieksieieva T,
Kravchenko I,
Hirsch A
(2023)
Toxicol. Rep., 10, 10.1016/j.toxrep.2023.02.009
Toxicol. Rep., 10, 10.1016/j.toxrep.2023.02.009
Selective Activation of TRPC6 Ion Channel by Metallated Type-B Polyprenylated Polycyclic Acylphloroglucinols
Publikation
Peslalz P,
Kraus F,
Izzo F,
Bleisch A,
El Hamdaoui Y,
Schulz I,
Kany A,
Hirsch A,
Friedland K,
Plietker B
(2023)
Manuscript, 10.26434/chemrxiv-2023-6w94r
Manuscript, 10.26434/chemrxiv-2023-6w94r
Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle
Publikation
Hamed M,
Abdelsamie A,
Rox K,
Schütz C,
Kany A,
Röhrig T,
Schmelz S,
Blankenfeldt W,
Arce-Rodriguez A,
Borrero-de Acuña J,
Jahn D,
Rademacher J,
Ringshausen F,
Cramer N,
Tümmler B,
Hirsch A,
Hartmann R,
Empting M
(2023)
Adv. Sci., Online, 10.1002/advs.202204443
Adv. Sci., Online, 10.1002/advs.202204443
Design of thiamine analogues for inhibition of thiamine diphosphate (ThDP)-dependent enzymes: Systematic investigation through Scaffold-Hopping and C2-Functionalisation
Publikation
Chan A,
Ho T,
Irfan R,
Hamid R,
Rudge E,
Iqbal A,
Turner A,
Hirsch A.,
Leeper F
(2023)
Bioorganic chemistry, 138, 10.1016/j.bioorg.2023.106602
Bioorganic chemistry, 138, 10.1016/j.bioorg.2023.106602
1-deoxy-D-xylulose-5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding
Publikation
Hamid R,
Adam S,
Lacour A,
Monjas L,
Köhnke J,
Hirsch A
(2023)
The Journal of biological chemistry, 10.1016/j.jbc.2023.105152, 37567475
The Journal of biological chemistry, 10.1016/j.jbc.2023.105152, 37567475
Low-Dimensional Metal-Organic Coordination Structures on Graphene
Publikation
Li J,
Solianyk L,
Schmidt N,
Baker B,
Gottardi S,
Moreno Lopez J,
Enache M,
Monjas L,
van der Vlag R,
Havenith R,
Hirsch A,
Stöhr M
(2019)
The journal of physical chemistry. C, Nanomaterials and interfaces, 123, 20, 12730-12735, 10.1021/acs.jpcc.9b00326, 31156737
The journal of physical chemistry. C, Nanomaterials and interfaces, 123, 20, 12730-12735, 10.1021/acs.jpcc.9b00326, 31156737
Surface state tunable energy and mass renormalization from homothetic quantum dot arrays
Publikation
Piquero-Zulaica I,
Li J,
Abd El-Fattah Z,
Solianyk L,
Gallardo I,
Monjas L,
Hirsch A,
Arnau A,
Ortega J,
Stöhr M,
Lobo-Checa J
(2019)
Nanoscale, 11, 48, 23132-23138, 10.1039/c9nr07365e, 31793595
Nanoscale, 11, 48, 23132-23138, 10.1039/c9nr07365e, 31793595
Hit evaluation of an α-helical peptide: Ala-scan, truncation and sidechain-to-sidechain macrocyclization of an RNA polymerase Inhibitor
Publikation
Kamal M,
Habib M,
Haupenthal J,
Hartmann R,
Empting M
(2019)
Biol. Chem., 400, 3, 333-342, 10.1515/hsz-2018-0333, 30657738
Biol. Chem., 400, 3, 333-342, 10.1515/hsz-2018-0333, 30657738
Comparing the Self-Assembly of Sexiphenyl-Dicarbonitrile on Graphite and Graphene on Cu(111)
Publikation
Schmidt N,
Li J,
Gottardi S,
Moreno-Lopez J,
Enache M,
Monjas L,
van der Vlag R,
Havenith R,
Hirsch A,
Stöhr M
(2019)
Chem. Eur. J., 25, 19, 5065-5070, 10.1002/chem.201806312, 30657213
Chem. Eur. J., 25, 19, 5065-5070, 10.1002/chem.201806312, 30657213
Novel 15-Lipoxygenase-1 Inhibitor Protects Macrophages from Lipopolysaccharide-Induced Cytotoxicity
Publikation
Guo H,
Verhoek I,
Prins G,
van der Vlag R,
van der Wouden P,
van Merkerk R,
Quax W,
Olinga P,
Hirsch A,
Dekker F
(2019)
Journal of medicinal chemistry, 62, 9, 4624-4637, 10.1021/acs.jmedchem.9b00212, 30964295
Journal of medicinal chemistry, 62, 9, 4624-4637, 10.1021/acs.jmedchem.9b00212, 30964295