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Design and Synthesis of Bioisosteres of Acylhydrazones as Stable Inhibitors of the Aspartic Protease Endothiapepsin
Publikation
Jumde V,
Mondal M,
Gierse R,
Unver M,
Magari F,
van Lier R,
Heine A,
Klebe G,
Hirsch A
(2018)
ChemMedChem, 13, 21, 2266-2270, 10.1002/cmdc.201800446
ChemMedChem, 13, 21, 2266-2270, 10.1002/cmdc.201800446
Delivery system for budesonide based on lipid-DNA
Publikation
Liu Y,
Bos I,
Oenema T,
Meurs H,
Maarsingh H,
Hirsch A
(2018)
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 130, 123-127, 10.1016/j.ejpb.2018.06.012, 29908939
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 130, 123-127, 10.1016/j.ejpb.2018.06.012, 29908939
Dynamic Proteoids Generated From Dipeptide-Based Monomers
Publikation
Liu Y,
Stuart M,
Buhler E,
Hirsch A
(2018)
Macromolecular rapid communications, 39, 13, 10.1002/marc.201800099, 29806088
Macromolecular rapid communications, 39, 13, 10.1002/marc.201800099, 29806088
Phage Display on the Anti-infective Target 1-Deoxy-d-xylulose-5-phosphate Synthase Leads to an Acceptor-Substrate Competitive Peptidic Inhibitor
Publikation
Marcozzi A,
Masini T,
Di Zhu,
Pesce D,
Illarionov B,
Fischer M,
Herrmann A,
Hirsch A
(2018)
ChemBioChem, 19, 1, 58-65, 10.1002/cbic.201700402, 29119720
ChemBioChem, 19, 1, 58-65, 10.1002/cbic.201700402, 29119720
Generation of Semi-Synthetic Shark IgNAR Single-Domain Antibody Libraries
Publikation
Grzeschik J,
Könning D,
Hinz S,
Krah S,
Schröter C,
Empting M,
Kolmar H,
Zielonka S
(2018)
Methods in molecular biology (Clifton, N.J.), 1701, 147-167, 10.1007/978-1-4939-7447-4_8, 29116504
Methods in molecular biology (Clifton, N.J.), 1701, 147-167, 10.1007/978-1-4939-7447-4_8, 29116504
Design, Synthesis, Antimicrobial Activity, and Molecular Docking of Some New Diclofenac Derivatives
Publikation
Tolba M,
Hamed M,
Sayed M,
Kamal El-Dean A,
Abdel-Mohsen S,
Ibrahim O,
Elgaher W,
Hirsch A,
Saddik A
(2022)
Polycyclic Aromatic Compounds, 1-16, 10.1080/10406638.2022.2102661
Polycyclic Aromatic Compounds, 1-16, 10.1080/10406638.2022.2102661
N-Aryl Mercaptopropionamides as Broad-Spectrum Inhibitors of Metallo-β-Lactamases
Publikation
Kaya C,
Konstantinovic J,
Kany A,
Andreas A,
Kramer J,
Brunst S,
Weizel L,
Rotter M,
Frank D,
Yahiaoui S,
Müller R,
Hartmann R,
Haupenthal J,
Proschak E,
Wichelhaus T,
Hirsch A
(2022)
Journal of medicinal chemistry, 65, 5, 3913-3922, 10.1021/acs.jmedchem.1c01755, 35188771
Journal of medicinal chemistry, 65, 5, 3913-3922, 10.1021/acs.jmedchem.1c01755, 35188771
Design and Synthesis of Novel Bis-Imidazolyl Phenyl Butadiyne Derivatives as HCV NS5A Inhibitors
Publikation
Hamdy J,
Emadeldin N,
Hamed M,
Frakolaki E,
Katsamakas S,
Vassilaki N,
Zoidis G,
Hirsch A,
Abdel-Halim M,
Abadi A
(2022)
Pharmaceuticals, 15, 5, 10.3390/ph15050632, 35631457
Pharmaceuticals, 15, 5, 10.3390/ph15050632, 35631457
N-Aryl-2-iso-butylmercaptoacetamides: the discovery of highly potent and selective inhibitors of Pseudomonas aeruginosa virulence factor LasB and Clostridium histolyticum virulence factor ColH
Publikation
Voos K,
Yahiaoui S,
Konstantinovic J,
Schönauer E,
Alhayek A,
Sikandar A,
Si Chaib K,
Ramspoth T,
Rox K,
Haupenthal J,
Köhnke J,
Brandstetter H,
Ducho C,
Hirsch A
(2022)
ChemRxiv, 10.26434/chemrxiv-2022-fjrqr
ChemRxiv, 10.26434/chemrxiv-2022-fjrqr
Inhibition of Collagenase Q1 of Bacillus cereus as a Novel Antivirulence Strategy for the Treatment of Skin‐Wound Infections
Publikation
Alhayek A,
Khan E,
Schönauer E,
Däinghaus T,
Shafiei R,
Voos K,
Han M,
Ducho C,
Posselt G,
Wessler S,
Brandstetter H,
Haupenthal J,
del Campo A,
Hirsch A
(2022)
Adv. Therap., 10.1002/adtp.202100222
Adv. Therap., 10.1002/adtp.202100222