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Anti-inflammatory and analgesic activity of ointment based on dense ginger extract (Zingiber officinale)
Publikation
Kravchenko I,
Eberle L,
Nesterkina M,
Kobernik A
(2019)
J Herbmed Pharmacol, 8, 2, 126-132, 10.15171/jhp.2019.20
J Herbmed Pharmacol, 8, 2, 126-132, 10.15171/jhp.2019.20
Rational Adaptation of L3MBTL1 Inhibitors to Create Small-Molecule Cbx7 Antagonists
Publikation
Simhadri C,
Daze K,
Douglas S,
Milosevich N,
Monjas L,
Dev A,
Brown T,
Hirsch A,
Wulff J,
Hof F
(2019)
ChemMedChem, 14, 15, 1444-1456, 10.1002/cmdc.201900021, 31254321
ChemMedChem, 14, 15, 1444-1456, 10.1002/cmdc.201900021, 31254321
Fragment-Based Discovery of a Qualified Hit Targeting the Latency-Associated Nuclear Antigen of the Oncogenic Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8
Publikation
Kirsch P,
Jakob V,
Oberhausen K,
Stein S,
Cucarro I,
Schulz T,
Empting M
(2019)
Journal of medicinal chemistry, 62, 8, 3924-3939, 10.1021/acs.jmedchem.8b01827, 30888817
Journal of medicinal chemistry, 62, 8, 3924-3939, 10.1021/acs.jmedchem.8b01827, 30888817
Protein-Templated Dynamic Combinatorial Chemistry: Brief Overview and Experimental Protocol
Publikation
Hartman A,
Gierse R,
Hirsch A
(2019)
European journal of organic chemistry, 2019, 22, 3581-3590, 10.1002/ejoc.201900327, 31680778
European journal of organic chemistry, 2019, 22, 3581-3590, 10.1002/ejoc.201900327, 31680778
Replacement of an Indole Scaffold Targeting Human 15-Lipoxygenase-1 Using Combinatorial Chemistry
Publikation
Prismawan D,
van der Vlag R,
Guo H,
Dekker F,
Hirsch A
(2019)
HCA, 102, 5, 10.1002/hlca.201900040, 31231138
HCA, 102, 5, 10.1002/hlca.201900040, 31231138
1-Deoxy-D-xylulose 5-phosphate synthase: structural perspectives on an essential enzyme in isoprenoid biosynthesis
Publikation
Gawriljuk V,
Oerlemans R,
Reddem E,
Gierse R,
Hirsch A,
Groves M
(2025)
J. Struct. Biol., 217, 3, 10.1016/j.jsb.2025.108236, 40784416
J. Struct. Biol., 217, 3, 10.1016/j.jsb.2025.108236, 40784416
Tobramycin crosslinking improves the colloidal stability of arginine chitosan biodynamers for safe and efficient siRNA delivery
Publikation
Liu Y,
Biesel A,
Kamal M,
Latta L,
Loretz B,
Hirsch A,
Lee S,
Lehr C
(2025)
Int. J. Biol. Macromol., 311, Pt 1, 10.1016/j.ijbiomac.2025.143420, 40274164
Int. J. Biol. Macromol., 311, Pt 1, 10.1016/j.ijbiomac.2025.143420, 40274164
Domain adaptable language modeling of chemical compounds identifies potent pathoblockers for Pseudomonas aeruginosa
Publikation
Kallergis G,
Asgari E,
Empting M,
Hirsch A,
Klawonn F,
McHardy A
(2025)
Commun. Chem., 8, 1, 10.1038/s42004-025-01484-4, 40216964
Commun. Chem., 8, 1, 10.1038/s42004-025-01484-4, 40216964
Modular synthetic routes to biologically active indoles from lignin
Publikation
Castillo-Garcia A,
Haupenthal J,
Hirsch A,
Barta K
(2025)
Green Chem., 27, 25, 7506-7512, 10.1039/d5gc01003a, 40510740
Green Chem., 27, 25, 7506-7512, 10.1039/d5gc01003a, 40510740
Positive Charge in an Antimalarial Compound Unlocks Broad-Spectrum Antibacterial Activity
Publikation
Braun-Cornejo M,
Platteschorre M,
Vries V,
Bravo P,
Sonawane V,
Hamed M,
Haupenthal J,
Reiling N,
Rottmann M,
Piet D,
Maas P,
Diamanti E,
Hirsch A
(2025)
JACS Au, 5, 3, 1146-1156, 10.1021/jacsau.4c00935, 40151263
JACS Au, 5, 3, 1146-1156, 10.1021/jacsau.4c00935, 40151263