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Tracheal tuft cell-released leukotrienes promote antibacterial immune responses
Publikation
Elhawy M,
Wadood N,
Grammer M,
Betzold P,
Herrmann E,
Lanzilli G,
Biradli F,
Klozenbücher C,
Klein A,
Alakkam N,
Hollenhorst M,
Gaini-Rahimi K,
Evers S,
Kusumakshi S,
Wyatt A,
Kany A,
Becker S,
Bischoff M,
Flockerzi V,
Gudermann T,
Chubanov V,
Empting M,
Hirsch A,
Schneider C,
Boehm U,
Krasteva-Christ G
(2026)
Cell Reports, 45, 9, 10.1016/j.celrep.2026.117863, 42632019
Cell Reports, 45, 9, 10.1016/j.celrep.2026.117863, 42632019
Application of Dual Inhibition Concept within Looped Autoregulatory Systems toward Antivirulence Agents against Pseudomonas aeruginosa Infections
Publikation
Thomann A,
Mello Martins A,
Brengel C,
Empting M,
Hartmann R
(2016)
ACS chemical biology, 11, 5, 1279-86, 10.1021/acschembio.6b00117, 26882081
ACS chemical biology, 11, 5, 1279-86, 10.1021/acschembio.6b00117, 26882081
Exploring the chemical space of ureidothiophene-2-carboxylic acids as inhibitors of the quorum sensing enzyme PqsD from Pseudomonas aeruginosa
Publikation
Sahner J,
Empting M,
Kamal A,
Weidel E,
Groh M,
Börger C,
Hartmann R
(2015)
European journal of medicinal chemistry, 96, 14-21, 10.1016/j.ejmech.2015.04.007, 25874327
European journal of medicinal chemistry, 96, 14-21, 10.1016/j.ejmech.2015.04.007, 25874327
From in vitro to in cellulo: structure-activity relationship of (2-nitrophenyl)methanol derivatives as inhibitors of PqsD in Pseudomonas aeruginosa
Publikation
Storz M,
Allegretta G,
Kirsch B,
Empting M,
Hartmann R
(2014)
Organic & biomolecular chemistry, 12, 32, 6094-104, 10.1039/c4ob00707g, 24909330
Organic & biomolecular chemistry, 12, 32, 6094-104, 10.1039/c4ob00707g, 24909330
The One-Step Synthesis of Biologically Active Isochromans from Lignin-Derived Aromatic Monomers in Tunable Deep Eutectic Solvents
Publikation
Kottayi A,
Afanasenko A,
Castillo-Garcia A,
Elgaher W,
Haupenthal J,
Hirsch A,
Barta K
(2025)
Chem. Eur. J., 10.1002/chem.202502769, 41351205
Chem. Eur. J., 10.1002/chem.202502769, 41351205
The influence of monoterpenoids and phenol derivatives on Drosophila melanogaster viability
Publikation
Nesterkina M,
Bilokon S,
Alieksieieva T,
Chubyk I,
Kravchenko I
(2018)
Journal of Asia-Pacific Entomology, 21, 3, 793-796, 10.1016/j.aspen.2018.06.004
Journal of Asia-Pacific Entomology, 21, 3, 793-796, 10.1016/j.aspen.2018.06.004
Targeting the Pseudomonas quinolone signal quorum sensing system for the discovery of novel anti-infective pathoblockers
Publikation
Schütz C,
Empting M
(2018)
Beilstein journal of organic chemistry, 14, 2627-2645, 10.3762/bjoc.14.241, 30410625
Beilstein journal of organic chemistry, 14, 2627-2645, 10.3762/bjoc.14.241, 30410625
Druggability Assessment of Targets Used in Kinetic Target-Guided Synthesis
Publikation
Unver M,
Gierse R,
Ritchie H,
Hirsch A
(2018)
Journal of medicinal chemistry, 61, 21, 9395-9409, 10.1021/acs.jmedchem.8b00266, 29873484
Journal of medicinal chemistry, 61, 21, 9395-9409, 10.1021/acs.jmedchem.8b00266, 29873484
Design and Synthesis of Bioisosteres of Acylhydrazones as Stable Inhibitors of the Aspartic Protease Endothiapepsin
Publikation
Jumde V,
Mondal M,
Gierse R,
Unver M,
Magari F,
van Lier R,
Heine A,
Klebe G,
Hirsch A
(2018)
ChemMedChem, 13, 21, 2266-2270, 10.1002/cmdc.201800446
ChemMedChem, 13, 21, 2266-2270, 10.1002/cmdc.201800446
Delivery system for budesonide based on lipid-DNA
Publikation
Liu Y,
Bos I,
Oenema T,
Meurs H,
Maarsingh H,
Hirsch A
(2018)
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 130, 123-127, 10.1016/j.ejpb.2018.06.012, 29908939
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 130, 123-127, 10.1016/j.ejpb.2018.06.012, 29908939