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Discovery and Structure-Based Optimization of 2-Ureidothiophene-3-carboxylic Acids as Dual Bacterial RNA Polymerase and Viral Reverse Transcriptase Inhibitors
Publikation
Elgaher W,
Sharma K,
Haupenthal J,
Saladini F,
Pires M,
Real E,
Mely Y,
Hartmann R
(2016)
Journal of medicinal chemistry, 10.1021/acs.jmedchem.6b00730, 27339173
Journal of medicinal chemistry, 10.1021/acs.jmedchem.6b00730, 27339173
Structure-Activity Relationships of 2-Sufonylpyrimidines as Quorum-Sensing Inhibitors to Tackle Biofilm Formation and eDNA Release of Pseudomonas aeruginosa
Publikation
Thomann A,
Brengel C,
Börger C,
Kail D,
Steinbach A,
Empting M,
Hartmann R
(2016)
ChemMedChem, 11, 22, 2522-2533, 10.1002/cmdc.201600419, 27731921
ChemMedChem, 11, 22, 2522-2533, 10.1002/cmdc.201600419, 27731921
Furoates and thenoates inhibit pyruvate dehydrogenase kinase 2 allosterically by binding to its pyruvate regulatory site
Publikation
Masini T,
Birkaya B,
van Dijk S,
Mondal M,
Hekelaar J,
Jäger M,
van Terwisscha Scheltinga A,
Patel M,
Hirsch A,
Moman E
(2016)
Journal of enzyme inhibition and medicinal chemistry, 31, sup4, 170-175, 10.1080/14756366.2016.1201812, 27435185
Journal of enzyme inhibition and medicinal chemistry, 31, sup4, 170-175, 10.1080/14756366.2016.1201812, 27435185
Synthesis and Anticonvulsant Activity of Menthyl γ-Aminobutyrate
Publikation
Nesterkina M,
Kravchenko I
(2016)
Chem Nat Compd, 52, 2, 237-239, 10.1007/s10600-016-1604-9
Chem Nat Compd, 52, 2, 237-239, 10.1007/s10600-016-1604-9
Synthesis and Pharmacological Properties of Novel Esters Based on Monocyclic Terpenes and GABA
Publikation
Nesterkina M,
Kravchenko I
(2016)
Pharmaceuticals (Basel, Switzerland), 9, 2, 10.3390/ph9020032, 27304960
Pharmaceuticals (Basel, Switzerland), 9, 2, 10.3390/ph9020032, 27304960
Analgesic Activity of Novel GABA Esters after Transdermal Delivery
Publikation
Nesterkina M,
Kravchenko I
(2016)
Nat. Prod. Commun., 11, 10, 10.1177/1934578X1601101001
Nat. Prod. Commun., 11, 10, 10.1177/1934578X1601101001
Single-domain antibodies for biomedical applications
Publikation
Krah S,
Schröter C,
Zielonka S,
Empting M,
Valldorf B,
Kolmar H
(2016)
Immunopharmacol. Immunotoxicol., 38, 1, 21-8, 10.3109/08923973.2015.1102934, 26551147
Immunopharmacol. Immunotoxicol., 38, 1, 21-8, 10.3109/08923973.2015.1102934, 26551147
Synthesis and Anticonvulsant Activity of New Calix[4]Arene Derivatives Containing Gamma-Aminobutyric Acid Moieties
Publikation
Nesterkina M,
Alekseeva E,
Kravchenko I
(2016)
Pharm Chem J, 49, 12, 825-829, 10.1007/s11094-016-1380-7
Pharm Chem J, 49, 12, 825-829, 10.1007/s11094-016-1380-7
Proteoid Dynamers with Tunable Properties
Publikation
Liu Y,
Stuart M,
Buhler E,
Lehn J,
Hirsch A
(2016)
, 10.1002/ADFM.201601612
, 10.1002/ADFM.201601612
Towards the evaluation in an animal disease model: Fluorinated 17β-HSD1 inhibitors showing strong activity towards both the human and the rat enzyme
Publikation
Abdelsamie A,
Bey E,
Gargano E,
van Koppen C,
Empting M,
Frotscher M
(2015)
European journal of medicinal chemistry, 103, 56-68, 10.1016/j.ejmech.2015.08.030, 26322835
European journal of medicinal chemistry, 103, 56-68, 10.1016/j.ejmech.2015.08.030, 26322835