Suche
From in vitro to in cellulo: structure-activity relationship of (2-nitrophenyl)methanol derivatives as inhibitors of PqsD in Pseudomonas aeruginosa
Publikation
Storz M,
Allegretta G,
Kirsch B,
Empting M,
Hartmann R
(2014)
Organic & biomolecular chemistry, 12, 32, 6094-104, 10.1039/c4ob00707g, 24909330
Organic & biomolecular chemistry, 12, 32, 6094-104, 10.1039/c4ob00707g, 24909330
Fine-tuning Nanocarriers Specifically toward Cargo: A Competitive Study on Solubilizing Related Photosensitizers for Photodynamic Therapy
Publikation
Wieczorek S,
Remmler D,
Masini T,
Kochovski Z,
Hirsch A,
Börner H
(2017)
Bioconjugate chemistry, 28, 3, 760-767, 10.1021/acs.bioconjchem.6b00549, 28002941
Bioconjugate chemistry, 28, 3, 760-767, 10.1021/acs.bioconjchem.6b00549, 28002941
Molecular insight into specific 14-3-3 modulators: Inhibitors and stabilisers of protein-protein interactions of 14-3-3
Publikation
Hartman A,
Hirsch A
(2017)
European journal of medicinal chemistry, 136, 10.1016/j.ejmech.2017.04.058, 28549334
European journal of medicinal chemistry, 136, 10.1016/j.ejmech.2017.04.058, 28549334
Synthesis and Pharmacological Properties of Novel Esters Based on Monoterpenoids and Glycine
Publikation
Nesterkina M,
Kravchenko I
(2017)
Pharmaceuticals (Basel, Switzerland), 10, 2, 10.3390/ph10020047, 28524111
Pharmaceuticals (Basel, Switzerland), 10, 2, 10.3390/ph10020047, 28524111
Semi-synthetic vNAR libraries screened against therapeutic antibodies primarily deliver anti-idiotypic binders
Publikation
Könning D,
Rhiel L,
Empting M,
Grzeschik J,
Sellmann C,
Schröter C,
Zielonka S,
Dickgießer S,
Pirzer T,
Yanakieva D,
Becker S,
Kolmar H
(2017)
Sci. Rep., 7, 1, 10.1038/s41598-017-10513-9, 28852148
Sci. Rep., 7, 1, 10.1038/s41598-017-10513-9, 28852148
Pentapeptide‐rich peptidoglycan at the Bacillus subtilis cell‐division site
Publikation
Morales Angeles D,
Liu Y,
Hartman A,
Borisova M,
Sousa Borges A,
Kok N,
Beilharz K,
veening j,
Mayer C,
Hirsch A,
Scheffers D
(2017)
Molecular microbiology, 104, 2, 319-333, 10.1111/mmi.13629
Molecular microbiology, 104, 2, 319-333, 10.1111/mmi.13629
Camelid and shark single domain antibodies: structural features and therapeutic potential
Publikation
Könning D,
Zielonka S,
Grzeschik J,
Empting M,
Valldorf B,
Krah S,
Schröter C,
Sellmann C,
Hock B,
Kolmar H
(2017)
Current opinion in structural biology, 45, 10-16, 10.1016/j.sbi.2016.10.019, 27865111
Current opinion in structural biology, 45, 10-16, 10.1016/j.sbi.2016.10.019, 27865111
Designed Spiroketal Protein Modulation
Publikation
Scheepstra M,
Andrei S,
Unver M,
Hirsch A,
Leysen S,
Ottmann C,
Brunsveld L,
Milroy L
(2017)
Angewandte Chemie (International ed. in English), 56, 20, 5480-5484, 10.1002/anie.201612504, 28407400
Angewandte Chemie (International ed. in English), 56, 20, 5480-5484, 10.1002/anie.201612504, 28407400
Design and synthesis of thiamine analogues to study their binding to the ECF transporter for thiamine in bacteria
Publikation
Monjas L,
Swier L,
Voogd A,
Oudshoorn R,
Hirsch A,
Slotboom D
(2016)
Med. Chem. Commun., 7, 5, 966-971, 10.1039/C6MD00022C
Med. Chem. Commun., 7, 5, 966-971, 10.1039/C6MD00022C
Dissecting the Multiple Roles of PqsE in Pseudomonas aeruginosa Virulence by Discovery of Small Tool Compounds
Publikation
Zender M,
Witzgall F,
Drees S,
Weidel E,
Maurer C,
Fetzner S,
Blankenfeldt W,
Empting M,
Hartmann R
(2016)
ACS chemical biology, 10.1021/acschembio.6b00156, 27082157
ACS chemical biology, 10.1021/acschembio.6b00156, 27082157