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Gesucht nach "drug". Zeige Ergebnisse 431 bis 440 von 705.

Disrupting Kaposi's Sarcoma-Associated Herpesvirus (KSHV) Latent Replication with a Small Molecule Inhibitor

Publikation
Berwanger A, Stein S, Kany A, Gartner M, Loretz B, Lehr C, Hirsch A, Schulz T, Empting M (2023)
Journal of medicinal chemistry, 66, 15, 10782-10790, 10.1021/acs.jmedchem.3c00990, 37506283

Arg-biodynamers as antibiotic potentiators through interacting with Gram-negative outer membrane lipopolysaccharides

Publikation
Kamal M, Bassil J, Loretz B, Hirsch A, Lee S, Lehr C (2024)
Eur J Pharm Biopharm, 200, 10.1016/j.ejpb.2024.114336, 38795784

Aspherical and Spherical InvA497-Functionalized Nanocarriers for Intracellular Delivery of Anti-Infective Agents

Publikation
Castoldi A, Empting M, Rossi C, Mayr K, Dersch P, Hartmann R, Müller R, Gordon S, Lehr C (2018)
Pharm Res, 36, 1, 10.1007/s11095-018-2521-3, 30519925

Proteoid biodynamers for safe mRNA transfection via pH-responsive nanorods enabling endosomal escape

Publikation
Lee S, Nasr S, Rasheed S, Liu Y, Hartwig O, Kaya C, Boese A, Koch M, Herrmann J, Müller R, Loretz B, Buhler E, Hirsch A, Lehr C (2022)
Journal of controlled release : official journal of the Controlled Release Society, 353, 915-929, 10.1016/j.jconrel.2022.12.018, 36521693

Squalenyl Hydrogen Sulfate Nanoparticles for Simultaneous Delivery of Tobramycin and an Alkylquinolone Quorum Sensing Inhibitor Enable the Eradication of P. aeruginosa Biofilm Infections

Publikation
Ho D, Murgia X, Rossi C, Christmann R, Hüfner de Mello Martins A, Koch M, Andreas A, Herrmann J, Müller R, Empting M, Hartmann R, Desmaele D, Loretz B, Couvreur P, Lehr C (2020)
Angewandte Chemie (International ed. in English), 10.1002/anie.202001407, 32243047

An Outer Membrane Vesicle-Based Permeation Assay (OMPA) for Assessing Bacterial Bioavailability

Publikation
Richter R, Kamal M, Koch M, Niebuur B, Huber A, Goes A, Volz C, Vergalli J, Kraus T, Müller R, Schneider-Daum N, Fuhrmann G, Pagès J, Lehr C (2022)
Advanced healthcare materials, 11, 5, 10.1002/adhm.202101180, 34614289

Novel Compounds Targeting the RNA-Binding Protein HuR. Structure-Based Design, Synthesis, and Interaction Studies

Publikation
Della Volpe S, Nasti R, Queirolo M, Unver M, Jumde V, Dömling A, Vasile F, Potenza D, Ambrosio F, Costa G, Alcaro S, Zucal C, Provenzani A, Di Giacomo M, Rossi D, Hirsch A, Collina S (2019)
ACS Med. Chem. Lett., 10, 4, 615-620, 10.1021/acsmedchemlett.8b00600, 30996806

Discovery and optimization of thiazole-based quorum sensing inhibitors as potent blockers of Pseudomonas aeruginosa pathogenicity

Publikation
Abdelsamie A, Hamed M, Schütz C, Röhrig T, Kany A, Schmelz S, Blankenfeldt W, Hirsch A, Hartmann R, Empting M (2024)
Eur. J. Med. Chem., 276, 10.1016/j.ejmech.2024.116685, 39042991

Toward Anti-Herpesviral PROTACs: Assessing the Challenges for Targeted Protein Degradation on the Example of Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen

Publikation
Berwanger A, Stein S, Brandner S, Kany A, Heinz S, Loretz B, Lehr C, Hirsch A, Lermyte F, Schulz T, Empting* M (2025)
ChemMedChem, 10.1002/cmdc.202500758, 41252598

In-depth Profiling of MvfR-Regulated Small Molecules in Pseudomonas aeruginosa after Quorum Sensing Inhibitor Treatment

Publikation
Allegretta G, Maurer C, Eberhard J, Maura D, Hartmann R, Rahme L, Empting M (2017)
Frontiers in microbiology, 8, 10.3389/fmicb.2017.00924, 28596760