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The role of fluid dynamics, microstructure and mucociliary clearance in the micro- and macroscopic barrier properties of pulmonary mucus
Publikation
Kirch J
(2012)
Book
Book
The interplay of lung surfactant proteins and lipids assimilates the macrophage clearance of nanoparticles
Publikation
Ruge C,
Schaefer U,
Herrmann J,
Kirch J,
Cañadas O,
Echaide M,
Pérez-Gil J,
Casals C,
Müller R,
Lehr C
(2012)
PLoS ONE, 7, 7, 10.1371/journal.pone.0040775
PLoS ONE, 7, 7, 10.1371/journal.pone.0040775
In vitro characterization of the novel solubility enhancing excipient Soluplus®
Publikation
Linn M
(2012)
Book
Book
Screening of budesonide nanoformulations for treatment of inflammatory bowel disease in an inflamed 3D cell-culture model
Publikation
Leonard F,
Ali H,
Collnot E,
Crielaard B,
Lammers T,
Storm G,
Lehr C
(2012)
ALTEX, 29, 3, 275-285
ALTEX, 29, 3, 275-285
Pulmonary delivery and tissue distribution of aerosolized antisense 2'-O-Methyl RNA containing nanoplexes in the isolated perfused and ventilated rat lung
Publikation
Dong M,
Murdter T,
Philippi C,
Loretz B,
Schaefer U,
Lehr C,
Schwab M,
Ammon-Treiber S
(2012)
European Journal of Pharmaceutics and Biopharmaceutics, 81, 3, 478-85, 10.1016/j.ejpb.2012.04.022, 22565122
European Journal of Pharmaceutics and Biopharmaceutics, 81, 3, 478-85, 10.1016/j.ejpb.2012.04.022, 22565122
Mucociliary clearance of micro- and nanoparticles is independent of size, shape and charge-an ex vivo and in silico approach
Publikation
Kirch J,
Guenther M,
Doshi N,
Schaefer U,
Schneider M,
Mitragotri S,
Lehr C
(2012)
Journal of Controlled Release, 159, 1, 128-134, 10.1016/j.jconrel.2011.12.015
Journal of Controlled Release, 159, 1, 128-134, 10.1016/j.jconrel.2011.12.015
Uptake of nanoparticles by alveolar macrophages is triggered by surfactant protein A
Publikation
Ruge C,
Kirch J,
Cañadas O,
Schneider M,
Perez-Gil J,
Schaefer U,
Casals C,
Lehr C
(2011)
Nanomedicine: Nanotechnology, Biology, and Medicine, 7, 6, 690-693, 10.1016/j.nano.2011.07.009
Nanomedicine: Nanotechnology, Biology, and Medicine, 7, 6, 690-693, 10.1016/j.nano.2011.07.009
Propidium iodide labeling of nanoparticles as a novel tool for the quantification of cellular binding and uptake
Publikation
Neumeyer A,
Bukowski M,
Veith M,
Lehr C,
Daum N
(2011)
Nanomedicine: Nanotechnology, Biology, and Medicine, 7, 4, 410-419, 10.1016/j.nano.2010.12.007
Nanomedicine: Nanotechnology, Biology, and Medicine, 7, 4, 410-419, 10.1016/j.nano.2010.12.007
Interaction of metal oxide nanoparticles with lung surfactant protein A
Publikation
Schulze C,
Schaefer U,
Ruge C,
Wohlleben W,
Lehr C
(2011)
European Journal of Pharmaceutics and Biopharmaceutics, 77, 3, 376-383, 10.1016/j.ejpb.2010.10.013
European Journal of Pharmaceutics and Biopharmaceutics, 77, 3, 376-383, 10.1016/j.ejpb.2010.10.013
New hope for inflammatory bowel disease
Publikation
Collnot E,
Mell N,
Lehr C
(2011)
Deutsche Apotheker Zeitung, 151, 27, 60-63
Deutsche Apotheker Zeitung, 151, 27, 60-63