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Permutation Test (PT) and Tolerated Difference Test (TDT): two new, robust and powerful nonparametric tests for statistical comparison of dissolution profiles
Publikation
Gómez-Mantilla J,
Casabó V,
Schaefer U,
Lehr C
(2013)
Int. J. Pharm., 441, 1-2, 458-467, 10.1016/j.ijpharm.2012.11.008, 23194886
Int. J. Pharm., 441, 1-2, 458-467, 10.1016/j.ijpharm.2012.11.008, 23194886
Optical tweezers reveal relationship between microstructure and nanoparticle penetration of pulmonary mucus
Publikation
Kirch J,
Schneider A,
Abou B,
Hopf A,
Schaefer U,
Schneider M,
Schall C,
Wagner C,
Lehr C
(2012)
Proceedings of the National Academy of Sciences of the United States of America, 109, 45, 18355-18360, 10.1073/pnas.1214066109
Proceedings of the National Academy of Sciences of the United States of America, 109, 45, 18355-18360, 10.1073/pnas.1214066109
A three-dimensional coculture of enterocytes, monocytes and dendritic cells to model inflamed intestinal mucosa in vitro
Publikation
Leonard F,
Collnot E,
Lehr C
(2010)
Molecular pharmaceutics, 7, 6, 2103-2119, 10.1021/mp1000795
Molecular pharmaceutics, 7, 6, 2103-2119, 10.1021/mp1000795
A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms
Publikation
Schütz C,
Ho D,
Hamed M,
Abdelsamie A,
Röhrig T,
Herr C,
Kany A,
Rox K,
Schmelz S,
Siebenbürger L,
Wirth M,
Börger C,
Yahiaoui S,
Bals R,
Scrima A,
Blankenfeldt W,
Horstmann J,
Christmann R,
Murgia X,
Koch M,
Berwanger A,
Loretz B,
Hirsch A,
Hartmann R,
Lehr C,
Empting M
(2021)
Advanced science (Weinheim, Baden-Wurttemberg, Germany), 8, 12, 10.1002/advs.202004369, 34165899
Advanced science (Weinheim, Baden-Wurttemberg, Germany), 8, 12, 10.1002/advs.202004369, 34165899
A hydrogel-based in vitro assay for the fast prediction of antibiotic accumulation in Gram-negative bacteria
Publikation
Richter R,
Kamal M,
García-Rivera M,
Kaspar J,
Junk M,
Elgaher W,
Srikakulam S,
Gress A,
Beckmann A,
Grißmer A,
Meier C,
Vielhaber M,
Kalinina O,
Hirsch A,
Hartmann R,
Brönstrup M,
Schneider-Daum N,
Lehr C
(2020)
Materials today. Bio, 8, 10.1016/j.mtbio.2020.100084, 33313504
Materials today. Bio, 8, 10.1016/j.mtbio.2020.100084, 33313504
Transferring Microclusters of P. aeruginosa Biofilms to the Air-Liquid Interface of Bronchial Epithelial Cells for Repeated Deposition of Aerosolized Tobramycin
Publikation
Horstmann J,
Laric A,
Boese A,
Yildiz D,
Röhrig T,
Empting M,
Frank N,
Krug D,
Müller R,
Schneider-Daum N,
Souza Carvalho-Wodarz C,
Lehr C
(2022)
ACS infectious diseases, 8, 1, 137-149, 10.1021/acsinfecdis.1c00444, 34919390
ACS infectious diseases, 8, 1, 137-149, 10.1021/acsinfecdis.1c00444, 34919390
pH-Dependent morphology and optical properties of lysine-derived molecular biodynamers
Publikation
Lee S,
Kaya C,
Jang H,
Koch M,
Loretz B,
Buhler E,
Lehr C,
Hirsch A
(2020)
Mater. Chem. Front., 4, 3, 905-909, 10.1039/C9QM00651F
Mater. Chem. Front., 4, 3, 905-909, 10.1039/C9QM00651F
Micro-rheological properties of lung homogenates correlate with infection severity in a mouse model of Pseudomonas aeruginosa lung infection
Publikation
Murgia X,
Kany A,
Herr C,
Ho D,
Rossi C,
Bals R,
Lehr C,
Hirsch A,
Hartmann R,
Empting M,
Röhrig T
(2020)
Scientific Reports, 10, 1, 10.1038/s41598-020-73459-5, 33020513
Scientific Reports, 10, 1, 10.1038/s41598-020-73459-5, 33020513
Eap-functionalized liposomes as a bioinspired delivery system for oral delivery of colistin to treat intracellular Salmonella infection
Publikation
Menina S
(2021)
Book
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A pulmonary mucus surrogate for investigating antibiotic permeation and activity against Pseudomonas aeruginosa biofilms
Publikation
Frisch S,
Boese A,
Huck B,
Horstmann J,
Ho D,
Schwarzkopf K,
Murgia X,
Loretz B,
Souza Carvalho-Wodarz C,
Lehr C
(2021)
The Journal of antimicrobial chemotherapy, 76, 6, 1472-1479, 10.1093/jac/dkab068, 33712824
The Journal of antimicrobial chemotherapy, 76, 6, 1472-1479, 10.1093/jac/dkab068, 33712824