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Cell and tissue-based in vitro models for improving the development of oral inhalation drug products
Publikation
Hittinger M,
Schneider-Daum N,
Lehr C
(2017)
European Journal of Pharmaceutics and Biopharmaceutics, 118, 73-78, 10.1016/j.ejpb.2017.02.019
European Journal of Pharmaceutics and Biopharmaceutics, 118, 73-78, 10.1016/j.ejpb.2017.02.019
The virulence factor LecB varies in clinical isolates: consequences for ligand binding and drug discovery
Publikation
Sommer R,
Wagner S,
Varrot A,
Nycholat C,
Khaledi A,
Häussler S,
Paulson J,
Imberty A,
Titz A
(2016)
Chem Sci, 7, 8, 4990-5001, 10.1039/c6sc00696e, 30155149
Chem Sci, 7, 8, 4990-5001, 10.1039/c6sc00696e, 30155149
In situ drug release monitoring with a fiber-optic system: Overcoming matrix interferences using derivative spectrophotometry
Publikation
Guillot A,
Limberge M,
Krämer J,
Lehr C
(2013)
Dissolution Technologies, 20, 2, 15-19
Dissolution Technologies, 20, 2, 15-19
The Parkinson's Disease Drug Tolcapone and Analogues are Potent Glycomimetic Lectin Inhibitors of Pseudomonas aeruginosa LecA
Publikation
Leusmann S,
Siebs E,
Kuhaudomlarp S,
Varrot A,
Imberty A,
Kuhn B,
Lerner C,
Grether U,
Titz A
(2025)
Angewandte Chemie (International ed. in English), 64, 50, 10.1002/anie.202508864, 41178200
Angewandte Chemie (International ed. in English), 64, 50, 10.1002/anie.202508864, 41178200
Drug solubility in biorelevant media in the context of an inhalation-based biopharmaceutics classification system (iBCS)
Publikation
Floroiu A,
Loretz B,
Krämer J,
Lehr C
(2024)
Eur J Pharm Biopharm, 197, 10.1016/j.ejpb.2024.114206, 38316234
Eur J Pharm Biopharm, 197, 10.1016/j.ejpb.2024.114206, 38316234
Zebrafish: An Attractive Model to Study Staphylococcus aureus Infection and Its Use as a Drug Discovery Tool
Publikation
Rasheed S,
Fries F,
Müller R,
Herrmann J
(2021)
Pharmaceuticals, 14, 6, 10.3390/ph14060594
Pharmaceuticals, 14, 6, 10.3390/ph14060594
3D printed tablets loaded with polymeric nanocapsules: An innovative approach to produce customized drug delivery systems
Publikation
Beck R,
Chaves P,
Goyanes A,
Vukosavljevic B,
Buanz A,
Windbergs M,
Basit A,
Gaisford S
(2017)
International journal of pharmaceutics, 528, 1-2, 268-279, 10.1016/j.ijpharm.2017.05.074, 28583328
International journal of pharmaceutics, 528, 1-2, 268-279, 10.1016/j.ijpharm.2017.05.074, 28583328
Compounds Interfering with Embryonic Lethal Abnormal Vision (ELAV) Protein-RNA Complexes: An Avenue for Discovering New Drugs
Publikation
Nasti R,
Rossi D,
Amadio M,
Pascale A,
Unver M,
Hirsch A,
Collina S
(2017)
Journal of medicinal chemistry, 60, 20, 8257-8267, 10.1021/acs.jmedchem.6b01871, 28587461
Journal of medicinal chemistry, 60, 20, 8257-8267, 10.1021/acs.jmedchem.6b01871, 28587461
Solid Phase Extraction as an Innovative Separation Method for Measuring Free and Entrapped Drug in Lipid Nanoparticles
Publikation
Guillot A,
Couffin A,
Sejean X,
Navarro F,
Limberger M,
Lehr C
(2015)
Pharmaceutical research, 32, 12, 3999-4009, 10.1007/s11095-015-1761-8
Pharmaceutical research, 32, 12, 3999-4009, 10.1007/s11095-015-1761-8
Preclinical safety and efficacy models for pulmonary drug delivery of antimicrobials with focus on in vitro models
Publikation
Hittinger M,
Juntke J,
Kletting S,
Schneider-Daum N,
de Souza Carvalho C,
Lehr C
(2015)
Advanced Drug Delivery Reviews, 85, 44-56, 10.1016/j.addr.2014.10.011, 25453270
Advanced Drug Delivery Reviews, 85, 44-56, 10.1016/j.addr.2014.10.011, 25453270