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Publikations-Highlights

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Functional Materials to Overcome Bacterial Barriers and Models to Advance Their Development

HypoRiPPAtlas as an Atlas of hypothetical natural products for mass spectrometry database search

Discovery and Characterization of a Myxobacterial Lanthipeptide with Unique Biosynthetic Features and Anti-inflammatory Activity

Atlas of the aging mouse brain reveals white matter as vulnerable foci

Revision of the Absolute Configurations of Chelocardin and Amidochelocardin

3D bioprinting of E. coli MG1655 biofilms on human lung epithelial cells for building complex in vitro infection models

Isolation, (bio)synthetic studies and evaluation of antimicrobial properties of drimenol-type sesquiterpenes of Termitomyces fungi

Characterizing expression changes in noncoding RNAs during aging and heterochronic parabiosis across mouse tissues

A Monoclonal Human Alveolar Epithelial Cell Line (“Arlo”) with Pronounced Barrier Function for Studying Drug Permeability and Viral Infections

Persicamidines—Unprecedented Sesquarterpenoids with Potent Antiviral Bioactivity against Coronaviruses

Thiamyxins: Structure and Biosynthesis of Myxobacterial RNA-Virus Inhibitors

Unusual peptide-binding proteins guide pyrroloindoline alkaloid formation in crocagin biosynthesis

Natural Products Lysobactin and Sorangicin A Show In Vitro Activity against Mycobacterium abscessus Complex

Publikationsdatenbank

2026

Discovery, engineering, and applications of amino acid and peptide prenyltransferases

Hubrich F (2026)

Nat. Prod. Rep.DOI: 10.1039/D5NP00075K

Phylogeny-Aware Metabologenomics Accurately Assigns Natural Products to Biosynthetic Gene Clusters

Boldt J, Porten C, Haeckl F, Hug J, Panter F, Steglich M, Wink J, Overmann J, Göker M, Krug D, Müller R, Nübel U (2026)

Microbial Biotechnology 19 (1)DOI: 10.1111/1751-7915.70298

Deep-Sea Genome Mining Reveals Cooperative ATP-Grasp Ligase-Directed Biosynthesis of Pentacyclic Myxomiditides with Potent Protease Inhibition

Li Y, Wang J, Zhang Z, Zhang Y, Müller R, Huo L (2026)

JACS Au 6 (1): 607-620DOI: 10.1021/jacsau.5c01626

Unveiling the Chemical Space of Astin-Type Peptides in Aster Tataricus, Cyanodermella Asteris, and Talaromyces Islandicus

Uka V, Tang S, Ohlrogge J, Sester A, Einsiedler M, Ludwig-Müller J, Gulder T (2026)

Chem. Eur. J.DOI: 10.1002/chem.202503340

Design and Optimization of Simplified Inhibitors Targeting E. coli and K. pneumoniae IspE

Walsh D, Hamid R, Giele T, Rottmann M, Hirsch A, Hamed M, Reiling N (2026)

RSC Med. Chem.DOI: 10.1039/D5MD00874C

2025

Discovery and Total Synthesis of Crossiguanipyrazines with Potent Activity Against Mycobacterium tuberculosis

Zhao H, Bickel E, Liu J, Yang X, Dal Molin M, Chhen J, Liu S, Sui H, Bian X, Wei X, …, Kazmaier U, Fu C (2025)

Angewandte Chemie (International ed. in English) 64 (52)DOI: 10.1002/anie.202513977

Impulse für die Antiinfektiva‐Forschung: ICA2025 in Saarbrücken

Kiefer A, Bader C, Beemelmanns C (2025)

Nachr Chem 73 (9): 89-89DOI: 10.1002/nadc.20254152454

Antiinfektiva-Forschung: Rückkehr in ein goldenes Zeitalter?

Bader C, Beemelmanns C, Kiefer A (2025)

Biospektrum 31 (5): 483-483DOI: 10.1007/s12268-025-2540-7

Saarvienin A - A Novel Glycopeptide with Potent Activity against Drug-resistant Bacteria

Kaur A, Guerrero-Garzón J, Rasheed S, Zehl M, Fries F, Morgenstern B, Zotchev S, Müller R (2025)

Angewandte Chemie (International ed. in English)DOI: 10.1002/anie.202425588

Natural products chlorotonils exert a complex antibacterial mechanism and address multiple targets

Deschner F, Mostert D, Daniel J, Voltz A, Schneider D, Khangholi N, Bartel J, Pessanha de Carvalho L, Brauer M, Gorelik T, …, Müller R, Herrmann J (2025)

Cell Chem. Biol.DOI: 10.1016/j.chembiol.2025.03.005

Dipeptidic Phosphonates: Potent Inhibitors of Pseudomonas aeruginosa Elastase B Showing Efficacy in a Murine Keratitis Model

Kiefer A, Schütz C, Englisch C, Kolling D, Speicher S, Kany A, Shafiei R, Wadood N, Aljohmani A, Wirschem N, …, Haupenthal J, Hirsch A (2025)

Adv. Sci.DOI: 10.1002/advs.202411807

Targeting IspD for Anti-infective and Herbicide Development: Exploring Its Role, Mechanism, and Structural Insights

Willocx D, Diamanti E, Hirsch A (2025)

Journal of medicinal chemistryDOI: 10.1021/acs.jmedchem.4c01146

1,2,4-Triazole-Based First-in-Class Non-Nucleoside Inhibitors of the Bacterial Enzyme MraY

Berida T, Huang T, Weck S, Lutz M, McKee S, Kagerah N, Manning D, Jahan M, Mishra S, Herrmann J, …, Ducho C, Roy S (2025)

ACS bio & med chem Au 5 (6): 966-981DOI: 10.1021/acsbiomedchemau.5c00158

Toward Anti-Herpesviral PROTACs: Assessing the Challenges for Targeted Protein Degradation on the Example of Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen

Berwanger A, Stein S, Brandner S, Kany A, Heinz S, Loretz B, Lehr C, Hirsch A, Lermyte F, Schulz T, Empting* M (2025)

ChemMedChemDOI: 10.1002/cmdc.202500758

Design, Synthesis, and Biological Evaluation of Mono- and Diamino-Substituted Squaramide Derivatives as Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthase

Palme P, Grover S, Abdelaziz R, Mann L, Kany A, Ouologuem L, Bartel K, Sonnenkalb L, Reiling N, Hirsch A, …, Imming P, Richter A (2025)

J. Med. Chem. 68 (23): 25274-25289DOI: 10.1021/acs.jmedchem.5c02284

Fragment Based Drug Discovery by Microscale Thermophoresis Targeting Klebsiella pneumoniae and Escherichia coli IspE

Walsh D, Willocx D, Hamid R, Hamed M, Hirsch A (2025)

Drug design, development and therapy 19: 11345-11353DOI: 10.2147/DDDT.S538771

Microbial Cross-Talk: Unlocking the Cytochalasin Diversity from a Termite-Associated Xylaria

Dayras M, Liu Y, Kochems R, Kruijff M, Balluff S, Rasheed S, Kany A, Herrmann J, Götze S, Morgenstern B, …, Müller R, Beemelmanns C (2025)

JACS AuDOI: 10.1021/jacsau.5c01093

The One-Step Synthesis of Biologically Active Isochromans from Lignin-Derived Aromatic Monomers in Tunable Deep Eutectic Solvents

Kottayi A, Afanasenko A, Castillo-Garcia A, Elgaher W, Haupenthal J, Hirsch A, Barta K (2025)

Chem. Eur. J.DOI: 10.1002/chem.202502769

Comparative metagenomic analysis on COPD and health control samples reveals taxonomic and functional motifs

Chen G, Wiegand C, Willett A, Herr C, Müller R, Bals R, Kalinina O (2025)

Frontiers in microbiology 16DOI: 10.3389/fmicb.2025.1636322

Engineering an Artificial Myxopyronin Derivative with Enhanced Metabolic Stability via Mutasynthesis

Kiefer A, Voltz A, Scherzer D, Reberšek R, Kany A, Prosser G, Neuber M, Reiling N, Hirsch A, Müller R (2025)

JACS AuDOI: 10.1021/jacsau.5c00950

Gb-piscidin: A novel antimicrobial and immunostimulant peptide from gilthead seabream (Sparus aurata) - Identification, tissue-specific expression, recombinant production, and biological evaluation

Berenjkar N, Kalbassi M, Hosseinkhani S, Beemelmanns C, Moghaddam J (2025)

Fish & shellfish immunology 169DOI: 10.1016/j.fsi.2025.111049

Tundrisphaera macrotermitis sp. nov., a novel member of the family Isosphaeraceae isolated from the gut of a fungus-growing termite

Kallscheuer N, Carlstedt K, Hammer J, Haufschild T, Benndorf R, Beer Z, Poulsen M, Beemelmanns C, Jogler C (2025)

Sci. Rep. 15 (1)DOI: 10.1038/s41598-025-20237-w

Genome-Mining Based Discovery of Pyrrolomycin K and L from the Termite-Associated Micromonospora sp. RB23

Lin M, Kruijff M, Poulsen M, Beemelmanns C (2025)

Journal of natural productsDOI: 10.1021/acs.jnatprod.5c01051

Biosynthesis of the Biphenomycin Family of Potent Antibiotics

Strunk E, Lobert A, Khorovich T, Guzman Lucio K, Richarz R, Hohmann M, D'Agostino P, Gulder T (2025)

Angew. Chem. Int. Ed.DOI: 10.1002/anie.202516156

Lignin-derived guaiacols as platform chemicals for the modular synthesis of 1,2,3,4-tetrahydroquinolines and benzomorpholines

Castillo-Garcia A, Haupenthal J, Hirsch A, Barta K (2025)

RSC sustainability 3 (9): 4039-4048DOI: 10.1039/d5su00151j

Modular synthetic routes to biologically active indoles from lignin

Castillo-Garcia A, Haupenthal J, Hirsch A, Barta K (2025)

Green Chem. 27 (25): 7506-7512DOI: 10.1039/d5gc01003a

Direct monitoring of intracellular polymer degradation via BODIPY dynamic dequenching

Bassil J, Kamal M, Gabelmann A, Christoulaki A, Koch M, Hamed M, Loretz B, Gallei M, Buhler E, Lehr C, Hirsch A, Lee S (2025)

Mater. Des. 256DOI: 10.1016/j.matdes.2025.114240

Tobramycin crosslinking improves the colloidal stability of arginine chitosan biodynamers for safe and efficient siRNA delivery

Liu Y, Biesel A, Kamal M, Latta L, Loretz B, Hirsch A, Lee S, Lehr C (2025)

Int. J. Biol. Macromol. 311 (Pt 1)DOI: 10.1016/j.ijbiomac.2025.143420

1-Deoxy-D-xylulose 5-phosphate synthase: structural perspectives on an essential enzyme in isoprenoid biosynthesis

Gawriljuk V, Oerlemans R, Reddem E, Gierse R, Hirsch A, Groves M (2025)

J. Struct. Biol. 217 (3)DOI: 10.1016/j.jsb.2025.108236

Targeting isoprenoid-precursor biosynthesis in Klebsiella pneumoniae: Design, synthesis and evaluation of 1-deoxy-D-xylulose 5-phosphate synthase (DXPS) inhibitors

Eisa S, Lacour A, Johannsen S, Hamid R, Raj P, Heinz D, Hamed M, Diamanti E, Hirsch A (2025)

Bioorg. Chem. 164DOI: 10.1016/j.bioorg.2025.108877

Role of Electrostatics in Metal–Organic Junctions on Surfaces: para -Hexaphenyl-dicarbonitrile on Au(111)

Pérez Paz A, Mowbray D, Gottardi S, Solianyk L, Li J, Monjas L, Hirsch A, Stöhr M, Moreno-López J (2025)

Chem. Mater. 37 (18): 7115-7124DOI: 10.1021/acs.chemmater.5c01172

A Novel Antimalarial Agent that Inhibits Protein Synthesis in Plasmodium falciparum

Bravo P, Diamanti E, Hamed M, Bizzarri L, Wiedemar N, Passecker A, Brancucci N, Albisetti A, Gumpp C, Illarionov B, …, Rottmann M, Hirsch A (2025)

Angew. Chem. Int. Ed. (64)DOI: 10.1002/anie.202514085

Newly identified properties of known pharmaceuticals and myxobacterial small molecules revealed by screening for autophagy modulators

Fichtner J, Beer Y, Ramm H, Mühlen S, Surup F, Herrmann J, Meister T, Pfaender S, Bilitewski U, Brönstrup M, …, Eskelinen E, Schmitz I (2025)

FEBS JDOI: 10.1111/febs.70243

Adaptations of Gram-Negative and Gram-Positive Probiotic Bacteria in Engineered Living Materials

Tadimarri V, Tyagi T, Duong C, Rasheed S, Müller R, Sankaran S (2025)

ACS biomaterials science & engineering 11 (6): 3773-3784DOI: 10.1021/acsbiomaterials.5c00325

Structures, biosynthetic pathways, and biological significance of bacterial aryl-heterocycle metallophores with emphasis on yersiniabactin-type derivatives

Kruijff M, Götze S, Beemelmanns C (2025)

Nat. Prod. Rep.DOI: 10.1039/D5NP00045A

Investigations into the biosynthesis of stieleriacines and related N-acyl tyrosines by comparative genomics, knock-out studies and total synthesis of epi-stieleriacine C

Sauer M, Staack M, Balluff S, Jogler C, Kallscheuer N, Beemelmanns C (2025)

Commun Chem 8 (1)DOI: 10.1038/s42004-025-01654-4

MITE: the Minimum Information about a Tailoring Enzyme database for capturing specialized metabolite biosynthesis

Rutz A, Probst D, Aguilar C, Akiyama D, Alberti F, Augustijn H, Avalon N, Beemelmanns C, Barbieri H, Biermann F, …, Medema M, Zdouc M (2025)

Nucleic Acids ResearchDOI: 10.1093/nar/gkaf969

Anti-adipogenic effects of N-acetyltyramine from termite-associated Streptomyces sp. M45

Jeong S, He M, Kim M, Nam K, Poulsen M, Beemelmanns C, Kang K, Kim K (2025)

Org. Biomol. Chem.DOI: 10.1039/D5OB01062D

Efficient and Selective Biosynthesis of a Precursor-Directed FK506 Analogue: Paving the Way for Click Chemistry

Goranovic D, Jenko B, Ramšak B, Podgoršek Berke A, Bedrac L, Horvat J, Šala M, Makuc D, Carriche G, Silva L, …, Fujs Š, Petkovic H (2025)

Journal of natural products 88 (3): 619-630DOI: 10.1021/acs.jnatprod.4c00394

Milestones in the development of Myxococcus xanthus as a model multicellular bacterium

Kroos L, Wall D, Islam S, Whitworth D, Muñoz-Dorado J, Higgs P, Singer M, Mauriello E, Treuner-Lange A, Søgaard-Andersen L, …, Velicer G, Nan B (2025)

J. Bacteriol. 207 (7)DOI: 10.1128/jb.00071-25

A Chemo-Enzymatic Platform for Furanolide Synthesis and Functional Exploration

Ji X, Einsiedler M, D'Agostino P, Herrmann J, Müller R, Gulder T (2025)

J. Am. Chem. Soc.DOI: 10.1021/jacs.5c08354

CAMI Benchmarking Portal: online evaluation and ranking of metagenomic software

Meyer F, Robertson G, Deng Z, Koslicki D, Gurevich A, McHardy A (2025)

Nucleic Acids Research 53 (W1): 102-DOI: 10.1093/nar/gkaf369

A Chemo-Enzymatic Platform for Furanolide Synthesis and Functional Exploration

Ji X, Einsiedler M, D'Agostino P, Herrmann J, Müller R, Gulder T (2025)

ChemRxivDOI: 10.26434/chemrxiv-2025-90mp4

Tandem ketone reduction in pepstatin biosynthesis reveals an F420H2-dependent statine pathway

Mo J, Sikandar A, Zhao H, Bashiri G, Huo L, Empting M, Müller R, Fu C (2025)

Nat Commun 16 (1)DOI: 10.1038/s41467-025-59785-0

Total synthesis of a sorrentanone ester library and evaluation of its antimicrobial potential

Milzarek T, Gattwinkel F, Bogojevic S, Milivojevic D, Vojnovic S, Gulder T, Nikodinovic-Runic J (2025)

Sci. Rep. 15 (1)DOI: 10.1038/s41598-025-05360-y

Regioselective C─H Functionalization by the Combination of Enzymatic and Chemocatalytic Reactions in Water

Zhu R, Mo X, Gulder T, Gulder T (2025)

Angew. Chem. Int. Ed.DOI: 10.1002/anie.202504378

Second Generation Tiancimycin-Based Antibody–Drug Conjugates Enabled by Highly Efficient Semi-synthetic Approach Specifically Targeting B-Cell Malignancies

Kiefer A, Thirugnanasambantham P, Jin Y, Steele A, Hwang D, Jiang Y, Adhikari A, Yang D, Chang J, Tafesse R, …, Muthusamy N, Shen B (2025)

JACS AuDOI: 10.1021/jacsau.5c00353

Innovative zinc-binding inhibitors of Legionella pneumophila ProA reduce collagen and flagellin degradation, TLR5 evasion, and human lung tissue inflammation

Scheithauer L, Ornago C, Selmar J, Schütz C, Bianchi G, Kiefer A, Haupenthal J, Dellmann A, Huynh D, Zhang R, …, Hirsch A, Steinert M (2025)

European journal of medicinal chemistry 296DOI: 10.1016/j.ejmech.2025.117832

Engineering an Artificial Myxopyronin Derivative with Enhanced Metabolic Stability via Mutasynthesis

Kiefer A, Voltz A, Scherzer D, Reberšek R, Kany A, Prosser G, Neuber M, Reiling N, Hirsch A, Müller R (2025)

DOI: 10.26434/chemrxiv-2025-q4h0n

Domain adaptable language modeling of chemical compounds identifies potent pathoblockers for Pseudomonas aeruginosa

Kallergis G, Asgari E, Empting M, Hirsch A, Klawonn F, McHardy A (2025)

Commun. Chem. 8 (1)DOI: 10.1038/s42004-025-01484-4

Tailored phenyl ureas eradicate drug-resistant Mycobacterium tuberculosis by targeting mycolic acid cell wall assembly

Mostert D, Braun J, Zimmerman M, Engelhart C, Berndl S, Quoika P, Kany A, Proietto J, Penalva-Lopez S, Wallach J, …, Dartois V, Sieber S (2025)

Chem. Sci.DOI: 10.1039/d5sc02565f

40 Years of Natural Product Reports

Gulder T, Lim K (2025)

Nat. Prod. Rep. 42 (4): 647-648DOI: 10.1039/D5NP90012C

Positive Charge in an Antimalarial Compound Unlocks Broad-Spectrum Antibacterial Activity

Braun-Cornejo M, Platteschorre M, Vries V, Bravo P, Sonawane V, Hamed M, Haupenthal J, Reiling N, Rottmann M, Piet D, …, Diamanti E, Hirsch A (2025)

JACS Au 5 (3): 1146-1156DOI: 10.1021/jacsau.4c00935

Chemical Proteomics Reveals Human Off-Targets of Fluoroquinolone Induced Mitochondrial Toxicity

Reinhardt T, El Harraoui Y, Rothemann A, Jauch A, Müller-Deubert S, Köllen M, Risch T, Jacobs L, Müller R, Traube F, …, Bach N, Sieber S (2025)

Angewandte Chemie (International ed. in English)DOI: 10.1002/anie.202421424

Postulations for the Migration Behavior of Amino Acids as Cations in Capillary Zone Electrophoresis

Gross P, Huber T, Lunow I, Burkhard D, Seelert H, Müller R (2025)

ElectrophoresisDOI: 10.1002/elps.202400205

ClpP2 proteasomes and SpxA1 determine Listeria monocytogenes tartrolon B hyper-resistance

Engelgeh T, Wamp S, Rothe P, Herrmann J, Fischer M, Müller R, Halbedel S (2025)

PLOS Genetics 21 (4)DOI: 10.1371/journal.pgen.1011621

The fungal natural product class of the sorbicillinoids: structures, bioactivities, biosynthesis, and synthesis

Milzarek T, Gulder T (2025)

Nat. Prod. Rep. 42: 482-500DOI: 10.1039/D4NP00059E

Antibiotic–Polycationic Peptide Conjugation as an Effective Strategy to Overcome Daptomycin Resistance

Rasheed S, Umstätter F, Mühlberg E, Beijer B, Hertlein T, Klika K, Kleist C, Werner J, Domhan C, Bingel M, …, Mier W, Uhl P (2025)

Adv. Therap.DOI: 10.1002/adtp.202400473

Gromomycins: An Unprecedented Class of Triterpene Antibiotics Produced by a Novel Biosynthetic Pathway

Luzhetskyy A, Tistechok S, Bratiichuk D, Sucipto H, Gummerlich N, Stierhof M, Fries F, Müller R, Zapp J, Myronovskyi M, Gromyko O, Fedorenko V (2025)

Angewandte Chemie (International ed. in English)DOI: 10.1002/anie.202422270

MIBiG 4.0: Advancing biosynthetic gene cluster curation through global collaboration

Zdouc M, Blin K, Louwen N, Navarro J, Loureiro C, Bader C, Bailey C, Barra L, Booth T, Bozhüyük K, …, Weber T, Medema M (2025)

Nucleic Acids Research 53 (D1): 678-690DOI: 10.1093/nar/gkae1115

Discovery of a novel, selective CK2 inhibitor class with an unusual basic scaffold

Khalifa H, ElHady A, Liu T, Elgaher W, Filhol-Cochet O, Cochet C, Abadi A, Hamed M, Abdel-Halim M, Engel M (2025)

European journal of medicinal chemistry 282DOI: 10.1016/j.ejmech.2024.117048

A plug-and-play system for polycyclic tetramate macrolactam production and functionalization

Glöckle A, Schuler S, Einsiedler M, Gulder T (2025)

Microb. Cell Fact. 24 (1)DOI: 10.1186/s12934-024-02630-8

Heterologous Expression and Optimization of Fermentation Conditions for Recombinant Ikarugamycin Production

Evers J, Glöckle A, Wiegand M, Schuler S, Einsiedler M, Gulder T (2025)

Biotechnol. Bioeng. 122 (4): 974-982DOI: 10.1002/bit.28919

Homophenylalanine-derived benzo1,4diazepine-2,5-diones are strong bacterial quorum sensing inhibitors

Einsiedler M, Bogojevic S, Milivojevic D, Vojnovic S, Milcic M, Maslak V, Matura A, Gulder T, Nikodinovic-Runic J (2025)

Org. Biomol. Chem. 23 (4): 835-843DOI: 10.1039/d4ob01734j

Heterologous Expression of a Cryptic BGC from Bilophila sp. Provides Access to a Novel Family of Antibacterial Thiazoles

Hohmann M, Iliasov D, Larralde M, Johannes W, Janßen K, Zeller G, Mascher T, Gulder T (2025)

ACS Synth. Biol. 14 (3): 967-978DOI: 10.1021/acssynbio.5c00042

Expanding Polycyclic Tetramate Macrolactam (PoTeM) Core Structure Diversity by Chemo-Enzymatic Synthesis and Bioengineering

Schuler S, Einsiedler M, Evers J, Malay M, Uka V, Schneider S, Gulder T (2025)

Angew. Chem. Int. Ed. 64 (13)DOI: 10.1002/anie.202420335

The Maculalactone Biosynthetic Gene Cluster, a Cryptic Furanolide Pathway Revealed in Nodularia sp. NIES-3585

D’Agostino P, Castro R, Uka V, Saurav K, Milzarek T, Sester A, Schneider M, Gulder T (2025)

bioRxivDOI: 10.1101/2025.02.26.640319

BGC Atlas: a web resource for exploring the global chemical diversity encoded in bacterial genomes

Bagci C, Nuhamunada M, Goyat H, Ladanyi C, Sehnal L, Blin K, Kautsar S, Tagirdzhanov A, Gurevich A, Mantri S, …, Weber T, Ziemert N (2025)

Nucleic Acids Res 53 (D1): 618-DOI: 10.1093/nar/gkae953

From Dyrk1A inhibitors to a novel class of antiviral agents: Targeting Enterovirus EV-A71 with 2-aryl-substituted thiophene scaffolds

Keddis P, My Tu T, Scherer H, Kany A, Hafez D, Darwish S, Abadi A, Hirsch A, Engel M, Hamed M, Horng J, Abdel-Halim M (2025)

Eur. J. Med. Chem. 287DOI: 10.1016/j.ejmech.2025.117348

Unlocking the Antiviral Arsenal: Structure-Guided Optimization of Small-Molecule Inhibitors against RSV and hCoV-229E

Karhan C, Sake S, Gunesch A, Grethe C, Hellwinkel B, Köhler N, Kiefer A, Hapko U, Kany A, Pietschmann T, Hirsch A (2025)

European journal of medicinal chemistryDOI: 10.1016/j.ejmech.2025.117282

PEARL: Protein Eluting Alginate with Recombinant Lactobacilli

Tadimarri V, Blanch-Asensio M, Deshpande K, Baumann J, Baumann C, Müller R, Trujillo S, Sankaran S (2025)

Small (Weinheim an der Bergstrasse, Germany)DOI: 10.1002/smll.202408316

Uncovering the genetic basis of antiviral polyketide limocrocin biosynthesis through heterologous expression

Melnyk S, Stierhof M, Bratiichuk D, Fries F, Müller R, Rebets Y, Luzhetskyy A, Ostash B (2025)

Microb. Cell Fact. 24 (1)DOI: 10.1186/s12934-024-02621-9

Apo structure of Mycobacterium tuberculosis 1-deoxy-d-xylulose 5-phosphate synthase DXPS: Dynamics and implications for inhibitor design

Gawriljuk V, Alhayek A, Hirsch A, Groves M (2025)

Biochemical and Biophysical Research Communications 747DOI: 10.1016/j.bbrc.2024.151246

The PLSDB 2025 update: enhanced annotations and improved functionality for comprehensive plasmid research

Molano L, Hirsch P, Hannig M, Müller R, Keller A (2025)

Nucleic Acids Res 53 (D1): 189-DOI: 10.1093/nar/gkae1095