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Induction of Liver Size Reduction in Zebrafish Larvae by the Emerging Synthetic Cannabinoid 4F-MDMB-BINACA and Its Impact on Drug Metabolism

Park Y, Dahlem C, Meyer M, Kiemer A, Müller R, Herrmann J (2022)

Molecules (Basel, Switzerland) 27 (4)DOI: 10.3390/molecules27041290

An Outer Membrane Vesicle-Based Permeation Assay (OMPA) for Assessing Bacterial Bioavailability

Richter R, Kamal M, Koch M, Niebuur B, Huber A, Goes A, Volz C, Vergalli J, Kraus T, Müller R, …, Pagès J, Lehr C (2022)

Advanced healthcare materials 11 (5)DOI: 10.1002/adhm.202101180

N-Aryl Mercaptopropionamides as Broad-Spectrum Inhibitors of Metallo-β-Lactamases

Kaya C, Konstantinovic J, Kany A, Andreas A, Kramer J, Brunst S, Weizel L, Rotter M, Frank D, Yahiaoui S, …, Wichelhaus T, Hirsch A (2022)

Journal of medicinal chemistry 65 (5): 3913-3922DOI: 10.1021/acs.jmedchem.1c01755

Myxobacteria of the Cystobacterineae Suborder Are Producers of New Vitamin K2 Derived Myxoquinones

Panter F, Popoff A, Garcia R, Krug D, Müller R (2022)

Microorganisms 10 (3)DOI: 10.3390/microorganisms10030534

PLSDB: advancing a comprehensive database of bacterial plasmids

Schmartz G, Hartung A, Hirsch P, Kern F, Fehlmann T, Müller R, Keller A (2022)

Nucleic Acids Res 50 (D1): 273-DOI: 10.1093/nar/gkab1111

Metabolic profiling of S-praziquantel: Structure elucidation using the crystalline sponge method in combination with mass spectrometry and nuclear magnetic resonance

Rosenberger L, Jenniches J, Essen C, Khutia A, Kühn C, Marx A, Georgi K, Hirsch A, Hartmann R, Badolo L (2022)

Drug metabolism and disposition: the biological fate of chemicalsDOI: 10.1124/dmd.121.000663

Novel 2,4-disubstituted quinazoline analogs as antibacterial agents with improved cytotoxicity profile: Modification of the benzenoid part

Megahed S, Rasheed S, Herrmann J, El-Hossary E, El-Shabrawy Y, Abadi A, Engel M, Müller R, Abdel-Halim M, Hamed M (2022)

Bioorg Med Chem Lett 59DOI: 10.1016/j.bmcl.2022.128531

New Deoxyenhygrolides from Plesiocystis pacifica Provide Insights into Butenolide Core Biosynthesis

Hug J, Kjaerulff L, Garcia R, Müller R (2022)

Marine drugs 20 (1)DOI: 10.3390/md20010072

Sandacrabins - Structurally Unique Antiviral RNA Polymerase Inhibitors from a Rare Myxobacterium

Bader C, Panter F, Garcia R, Tchesnokov E, Haid S, Walt C, Spröer C, Kiefer A, Götte M, Overmann J, Pietschmann T, Müller R (2022)

Chem. Eur. J. 28 (10)DOI: 10.1002/chem.202104484

Inhibition of Collagenase Q1 of Bacillus cereus as a Novel Antivirulence Strategy for the Treatment of Skin‐Wound Infections

Alhayek A, Khan E, Schönauer E, Däinghaus T, Shafiei R, Voos K, Han M, Ducho C, Posselt G, Wessler S, …, del Campo A, Hirsch A (2022)

Adv. Therap.DOI: 10.1002/adtp.202100222

Bacteriomimetic Liposomes Improve Antibiotic Activity of a Novel Energy-Coupling Factor Transporter Inhibitor

Drost M, Diamanti E, Fuhrmann K, Goes A, Shams A, Haupenthal J, Koch M, Hirsch A, Fuhrmann G (2022)

Pharmaceutics 14 (1)DOI: 10.3390/pharmaceutics14010004

Biotechnological production optimization of argyrins - a potent immunomodulatory natural product class

Pogorevc D, Müller R (2022)

Microbial Biotechnology 15 (1): 353-369DOI: 10.1111/1751-7915.13959


Towards the sustainable discovery and development of new antibiotics

Miethke M, Pieroni M, Weber T, Brönstrup M, Hammann P, Halby L, Arimondo P, Glaser P, Aigle B, Bode H, …, Moser H, Müller R (2021)

Nat Rev Chem: 1-24DOI: 10.1038/s41570-021-00313-1

Improved broad-spectrum antibiotics against Gram-negative pathogens via darobactin biosynthetic pathway engineering

Groß S, Panter F, Pogorevc D, Seyfert C, Deckarm S, Bader C, Herrmann J, Müller R (2021)

Chem. Sci. 12 (35): 11882-11893DOI: 10.1039/d1sc02725e

In vivo and in vitro reconstitution of unique key steps in cystobactamid antibiotic biosynthesis

Groß S, Schnell B, Haack P, Auerbach D, Müller R (2021)

Nat Commun 12 (1)DOI: 10.1038/s41467-021-21848-3

The Sandarazols are Cryptic and Structurally Unique Plasmid-Encoded Toxins from a Rare Myxobacterium*

Panter F, Bader C, Müller R (2021)

Angewandte Chemie (International ed. in English) 60 (15): 8081-8088DOI: 10.1002/anie.202014671

Targeting the IspD Enzyme in the MEP Pathway: Identification of a Novel Fragment Class

Diamanti E, Hamed M, Lacour A, Bravo P, Illarionov B, Fischer M, Rottmann M, Witschel M, Hirsch A (2021)

ChemMedChemDOI: 10.1002/cmdc.202100679

Substrate-Inspired Fragment Merging and Growing Affords Efficacious LasB Inhibitors

Kaya C, Walter I, Yahiaoui S, Sikandar A, Alhayek A, Konstantinovic J, Kany A, Haupenthal J, Köhnke J, Hartmann R, Hirsch A (2021)

Angewandte Chemie (International ed. in English)DOI: 10.1002/anie.202112295

Targeting the energy-coupling factor (ECF) transporters: identification of new tool compounds

Diamanti E, Setyawati I, Bousis S, Souza P, mojas l, Swier l, Haupenthal J, Gibson P, Volz C, stanek w, …, slotboom d, Hirsch A (2021)

ChemRxivDOI: 10.26434/chemrxiv-2021-xq08b-v2

Redesigning of the cap conformation and symmetry of the diphenylethyne core to yield highly potent pan-genotypic NS5A inhibitors with high potency and high resistance barrier

Abdallah M, Hamed M, Frakolaki E, Katsamakas S, Vassilaki N, Bartenschlager R, Zoidis G, Hirsch A, Abdel-Halim M, Abadi A (2021)

European journal of medicinal chemistryDOI: 10.1016/j.ejmech.2021.114034

Unveiling Adatoms in On-Surface Reactions: Combining Scanning Probe Microscopy with van't Hoff Plots

Moreno-López J, Pérez Paz A, Gottardi S, Solianyk L, Li J, Monjas L, Hirsch A, Mowbray D, Stöhr M (2021)

The journal of physical chemistry. C, Nanomaterials and interfaces 125 (18): 9847-9854DOI: 10.1021/acs.jpcc.1c03134

An efficient way to screen inhibitors of energy-coupling factor (ECF) transporters in bacteria uptake assay

Bousis S, Winkler S, Haupenthal J, Fulco F, Diamanti E, Hirsch A (2021)

ChemRxivDOI: 10.26434/chemrxiv-2021-b50gj

Genome-Guided Discovery of the First Myxobacterial Biarylitide Myxarylin Reveals Distinct C-N Biaryl Crosslinking in RiPP Biosynthesis

Hug J, Frank N, Walt C, Šenica P, Panter F, Müller R (2021)

Molecules 26 (24)DOI: 10.3390/molecules26247483

Structure of Escherichia coli cytochrome bd-II type oxidase with bound aurachin D

Grauel A, Kägi J, Rasmussen T, Makarchuk I, Oppermann S, Moumbock A, Wohlwend D, Müller R, Melin F, Günther S, …, Böttcher B, Friedrich T (2021)

Nat Commun 12 (1)DOI: 10.1038/s41467-021-26835-2

1st Spring Virtual Meeting on Medicinal Chemistry

Sousa M, Marques M, Faustino M (2021)

Chemistry Proceedings 4 (1)DOI: 10.3390/chemproc2021004001

Structure and Biosynthesis of Myxofacyclines: Unique Myxobacterial Polyketides Featuring Varing and Rare Heterocycles *

Popoff A, Hug J, Walesch S, Garcia R, Keller L, Müller R (2021)

Chem. Eur. J. 27 (67): 16654-16661DOI: 10.1002/chem.202103095

The natural product vioprolide A exerts anti-inflammatory actions through inhibition of its cellular target NOP14 and downregulation of importin-dependent NF-ĸB p65 nuclear translocation

Burgers L, Luong B, Li Y, Fabritius M, Michalakis S, Reichel C, Müller R, Fürst R (2021)

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 144DOI: 10.1016/j.biopha.2021.112255

Distinct Patterns of Blood Cytokines Beyond a Cytokine Storm Predict Mortality in COVID-19

Herr C, Mang S, Mozafari B, Guenther K, Speer T, Seibert M, Srikakulam S, Beisswenger C, Ritzmann F, Keller A, …, Lepper P, Bals R (2021)

Journal of inflammation research 14: 4651-4667DOI: 10.2147/JIR.S320685

Design, synthesis, and biological evaluation of novel benzimidazole derivatives as sphingosine kinase 1 inhibitor

Khairat S, Omar M, Ragab F, Roy S, Turab Naqvi A, Abdelsamie A, Hirsch A, Galal S, Hassan M, El Diwani H (2021)

Archiv der Pharmazie 354 (9)DOI: 10.1002/ardp.202100080

Physiologically Based Pharmacokinetic/Pharmacodynamic Model for the Treatment of Dengue Infections Applied to the Broad Spectrum Antiviral Soraphen A

Rox K, Heyner M, Krull J, Harmrolfs K, Rinne V, Hokkanen J, Perez Vilaro G, Díez J, Müller R, Kröger A, Sugiyama Y, Brönstrup M (2021)

ACS Pharmacol. Transl. Sci.DOI: 10.1021/acsptsci.1c00078

Identification of N,N-arylalkyl-picolinamide derivatives targeting the RNA-binding protein HuR, by combining biophysical fragment-screening and molecular hybridization

Della Volpe S, Linciano P, Listro R, Tumminelli E, Amadio M, Bonomo I, Elgaher W, Adam S, Hirsch A, Boeckler F, …, Rossi D, Collina S (2021)

Bioorganic chemistry 116DOI: 10.1016/j.bioorg.2021.105305

Expanding the Myxochelin Natural Product Family by Nicotinic Acid Containing Congeners

Frank N, Széles M, Akone S, Rasheed S, Hüttel S, Frewert S, Hamed M, Herrmann J, Schuler S, Hirsch A, Müller R (2021)

Molecules 26 (16)DOI: 10.3390/molecules26164929

N-Aryl mercaptoacetamides as potential multi-target inhibitors of metallo-β-lactamases (MBLs) and the virulence factor LasB from Pseudomonas aeruginosa

Yahiaoui S, Voos K, Haupenthal J, Wichelhaus T, Frank D, Weizel L, Rotter M, Brunst S, Kramer J, Proschak E, Ducho C, Hirsch A (2021)

RSC Med. Chem.DOI: 10.1039/D1MD00187F

Crystalline sponge affinity screening: A fast tool for soaking condition optimization without the need of X-ray diffraction analysis

Rosenberger L, Essen C, Khutia A, Kühn C, Georgi K, Hirsch A, Hartmann R, Badolo L (2021)

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 164DOI: 10.1016/j.ejps.2021.105884

Non-Carbohydrate Glycomimetics as Inhibitors of Calcium(II)-Binding Lectins

Kuhaudomlarp S, Siebs E, Shanina E, Topin J, Joachim I, da Silva Figueiredo Celestino Gomes P, Varrot A, Rognan D, Rademacher C, Imberty A, Titz A (2021)

Angew. Chem. Int. Ed. 60 (15): 8104-8114DOI: 10.1002/anie.202013217

The exo-β-N-acetylmuramidase NamZ from Bacillus subtilis is the founding member of a family of exo-lytic peptidoglycan hexosaminidases

Müller M, Calvert M, Hottmann I, Kluj R, Teufel T, Balbuchta K, Engelbrecht A, Selim K, Xu Q, Borisova M, Titz A, Mayer C (2021)

The Journal of biological chemistry 296DOI: 10.1016/j.jbc.2021.100519

Sesbanimide R, a Novel Cytotoxic Polyketide Produced by Magnetotactic Bacteria

Awal R, Haack P, Bader C, Riese C, Schüler D, Müller R (2021)

mBio 12 (3)DOI: 10.1128/mBio.00591-21

Drug delivery to the inflamed intestinal mucosa- targeting technologies and human cell culture models for better therapies of IBD

Olga H, Shetab Boushehri Maryam A, Shalaby Karim S, Brigitta L, Alf L, Claus-Michael L (2021)

Advanced Drug Delivery ReviewsDOI: 10.1016/j.addr.2021.113828

Development and evaluation of a quality control system based on transdermal electrical resistance for skin barrier function in vitro

Knoth K, Zäh R, Veldung B, Burgio D, Wiegand B, Smola H, Bock U, Lehr C, Hittinger M, Groß H (2021)

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)DOI: 10.1111/srt.12998

Second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane

Zamprogno P, Wüthrich S, Achenbach S, Thoma G, Stucki J, Hobi N, Schneider-Daum N, Lehr C, Huwer H, Geiser T, Schmid R, Guenat O (2021)

Communications Biology 4 (1)DOI: 10.1038/s42003-021-01695-0

Spray-dried lactose-leucine microparticles for pulmonary delivery of antimycobacterial nanopharmaceuticals

Thiyagarajan D, Huck B, Nothdurft B, Koch M, Rudolph D, Rutschmann M, Feldmann C, Hozsa C, Furch M, Besecke K, …, Loretz B, Lehr C (2021)

Drug delivery and translational research 11 (4): 1766-1778DOI: 10.1007/s13346-021-01011-7

Microbiota and cancer: In vitro and in vivo models to evaluate nanomedicines

Ladaycia A, Loretz B, Passirani C, Lehr C, Lepeltier E (2021)

Advanced Drug Delivery Reviews 170: 44-70DOI: 10.1016/j.addr.2020.12.015

Fucosylated lipid nanocarriers loaded with antibiotics efficiently inhibit mycobacterial propagation in human myeloid cells

Durán V, Grabski E, Hozsa C, Becker J, Yasar H, Monteiro J, Costa B, Koller N, Lueder Y, Wiegmann B, …, Graalmann T, Kalinke U (2021)

Journal of controlled release : official journal of the Controlled Release Society 334: 201-212DOI: 10.1016/j.jconrel.2021.04.012

A Custom-Made Device for Reproducibly Depositing Pre-metered Doses of Nebulized Drugs on Pulmonary Cells in vitro

Horstmann J, Thorn C, Carius P, Graef F, Murgia X, Souza Carvalho-Wodarz C, Lehr C (2021)

Frontiers in Bioengineering and Biotechnology 9DOI: 10.3389/fbioe.2021.643491

Formulation and evaluation of transdermal nanogel for delivery of artemether

Nnamani P, Ugwu A, Nnadi O, Kenechukwu F, Ofokansi K, Attama A, Lehr C (2021)

Drug delivery and translational research 11 (4): 1655-1674DOI: 10.1007/s13346-021-00951-4

Surfactant-Free Glibenclamide Nanoparticles: Formulation, Characterization and Evaluation of Interactions with Biological Barriers

Arrua E, Hartwig O, Ho D, Loretz B, Murgia X, Salomon C, Lehr C (2021)

Pharmaceutical research 38 (6): 1081-1092DOI: 10.1007/s11095-021-03056-2

Testing of aerosolized ciprofloxacin nanocarriers on cystic fibrosis airway cells infected with P. aeruginosa biofilms

Juntke J, Murgia X, Günday Türeli N, Türeli A, Thorn C, Schneider M, Schneider-Daum N, Souza Carvalho-Wodarz C, Lehr C (2021)

Drug delivery and translational research 11 (4): 1752-1765DOI: 10.1007/s13346-021-01002-8

Tobramycin Liquid Crystal Nanoparticles Eradicate Cystic Fibrosis-Related Pseudomonas aeruginosa Biofilms

Thorn C, Carvalho-Wodarz C, Horstmann J, Lehr C, Prestidge C, Thomas N (2021)

Small (Weinheim an der Bergstrasse, Germany) 17 (24)DOI: 10.1002/smll.202100531

Decoding (patho-)physiology of the lung by advanced in vitro models for developing novel anti-infectives therapies

Montefusco-Pereira C, Carvalho-Wodarz C, Seeger J, Kloft C, Michelet R, Lehr C (2021)

Drug Discovery Today 26 (1): 148-163DOI: 10.1016/j.drudis.2020.10.016

Analysis and Optimization of Two Film-Coated Tablet Production Processes by Computer Simulation: A Case Study

Hering S, Schäuble N, Buck T, Loretz B, Rillmann T, Stieneker F, Lehr C (2021)

Processes 9 (1)DOI: 10.3390/pr9010067

A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms

Schütz C, Ho D, Hamed M, Abdelsamie A, Röhrig T, Herr C, Kany A, Rox K, Schmelz S, Siebenbürger L, …, Lehr C, Empting M (2021)

Advanced science (Weinheim, Baden-Wurttemberg, Germany) 8 (12)DOI: 10.1002/advs.202004369

Drug delivery for fighting infectious diseases: a global perspective

Loretz B, Oh Y, Hudson S, Gu Z, Lehr C (2021)

Drug delivery and translational research 11 (4): 1316-1322DOI: 10.1007/s13346-021-01009-1

A pulmonary mucus surrogate for investigating antibiotic permeation and activity against Pseudomonas aeruginosa biofilms

Frisch S, Boese A, Huck B, Horstmann J, Ho D, Schwarzkopf K, Murgia X, Loretz B, Souza Carvalho-Wodarz C, Lehr C (2021)

The Journal of antimicrobial chemotherapy 76 (6): 1472-1479DOI: 10.1093/jac/dkab068

Extracellular vesicles as antigen carriers for novel vaccination avenues

Mehanny M, Lehr C, Fuhrmann G (2021)

Advanced Drug Delivery Reviews 173: 164-180DOI: 10.1016/j.addr.2021.03.016

Extracellular vesicles as novel assay tools to study cellular interactions of anti-infective compounds - A perspective

Richter R, Lehr C (2021)

Advanced Drug Delivery Reviews 173: 492-503DOI: 10.1016/j.addr.2021.04.010

Disease Models: Lung Models for Testing Drugs Against Inflammation and Infection

Carius P, Horstmann J, Souza Carvalho-Wodarz C, Lehr C (2021)

Handbook of experimental pharmacology 265: 157-186DOI: 10.1007/164_2020_366

Eap-functionalized liposomes as a bioinspired delivery system for oral delivery of colistin to treat intracellular Salmonella infection

Menina S (2021)


Zebrafish: An Attractive Model to Study Staphylococcus aureus Infection and Its Use as a Drug Discovery Tool

Rasheed S, Fries F, Müller R, Herrmann J (2021)

Pharmaceuticals 14 (6)DOI: 10.3390/ph14060594

“Clicking“ fragment leads to novel dual-binding cholinesterase inhibitors

Moleda Z, Zawadzka A, Czarnocki Z, Monjas L, Hirsch A, Budzianowski A, Maurin J (2021)

Bioorg Med ChemDOI: 10.1016/j.bmc.2021.116269

Structure and biosynthesis of sorangipyranone - a new γ-dihydropyrone from the myxobacterial strain MSr12020

Okoth D, Hug J, Mándi A, Kurtán T, Garcia R, Müller R (2021)

Journal of Industrial Microbiology & Biotechnology 48 (3-4)DOI: 10.1093/jimb/kuab029

Front Cover: Phosphonate as a Stable Zinc‐Binding Group for “Pathoblocker” Inhibitors of Clostridial Collagenase H (ColH) (ChemMedChem 8/2021)

Voos K, Schönauer E, Alhayek A, Haupenthal J, Andreas A, Müller R, Hartmann R, Brandstetter H, Hirsch A, Ducho C (2021)

ChemMedChem 16 (8): 1198-1198DOI: 10.1002/cmdc.202100229

Hit-optimization using target-directed dynamic combinatorial chemistry: Development of inhibitors of the anti-infective target 1-deoxy-D-xylulose-5-phosphate synthase

Jumde R, Guadigni M, Gierse R, Alhayek A, Di Zhu, Hamid Z, Johannsen S, Elgaher W, Neusens P, Nehls C, …, Reiling N, Hirsch A (2021)

Chemical ScienceDOI: 10.1039/D1SC00330E

miRMaster 2.0: multi-species non-coding RNA sequencing analyses at scale

Fehlmann T, Kern F, Laham O, Backes C, Solomon J, Hirsch P, Volz C, Müller R, Keller A (2021)

Nucleic Acids ResDOI: 10.1093/nar/gkab268

Search for the Active Ingredients from a 2-Aminothiazole DMSO Stock Solution with Antimalarial Activity

Ropponen H, Bader C, Diamanti E, Illarionov B, Rottmann M, Fischer M, Witschel M, Müller R, Hirsch A (2021)

ChemMedChem 16 (13): 2089-2093DOI: 10.1002/cmdc.202100067

Synergizing the potential of bacterial genomics and metabolomics to find novel antibiotics

Panter F, Bader C, Müller R (2021)

Chem. Sci. 12 (17): 5994-6010DOI: 10.1039/d0sc06919a

Targeting cellular fatty acid synthesis limits T helper and innate lymphoid cell function during intestinal inflammation and infection

Mamareli P, Kruse F, Lu C, Guderian M, Floess S, Rox K, Allan D, Carlyle J, Brönstrup M, Müller R, …, Sparwasser T, Lochner M (2021)

Mucosal Immunol. 14 (1): 164-176DOI: 10.1038/s41385-020-0285-7

Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis

Almeida L, Dhillon-LaBrooy A, Castro C, Adossa N, Carriche G, Guderian M, Lippens S, Dennerlein S, Hesse C, Lambrecht B, …, Moita L, Sparwasser T (2021)

Immunity 54 (1): 68-83DOI: 10.1016/j.immuni.2020.11.001

Stimulation of Probiotic Bacteria Induces Release of Membrane Vesicles with Augmented Anti-inflammatory Activity

Müller L, Kuhn T, Koch M, Fuhrmann G (2021)

ACS Appl. Bio Mater.DOI: 10.1021/acsabm.0c01136

Mastering the Gram-Negative Bacterial Barrier - Chemical Approaches to Increase Bacterial Bioavailability of Antibiotics

Ropponen H, Richter R, Hirsch A, Lehr C (2021)

Advanced Drug Delivery ReviewsDOI: 10.1016/j.addr.2021.02.014

Assessment of the rules related to gaining activity against Gram-negative bacteria

Ropponen H, Diamanti E, Siemens A, Illarionov B, Haupenthal J, Fischer M, Rottmann M, Witschel M, Hirsch A (2021)

RSC Med. Chem.DOI: 10.1039/D0MD00409J

Natural products in drug discovery: advances and opportunities

Atanasov A, Zotchev S, Dirsch V, Supuran C (2021)

Nature reviews. Drug discovery 20 (3): 200-216DOI: 10.1038/s41573-020-00114-z

Enhancing glycan stability via site-selective fluorination: modulating substrate orientation by molecular design

Axer A, Jumde R, Adam S, Faust A, Schäfers M, Fobker M, Koehnke J, Hirsch A, Gilmour R (2021)

Chem. Sci. 12 (4): 1286-1294DOI: 10.1039/D0SC04297H

Phosphonate as Stable Zinc-binding Group for Inhibitors of Clostridial Collagenase H (ColH) as Pathoblocker Agents

Voos K, Schönauer E, Alhayek A, Haupenthal J, Andreas A, Müller R, Hartmann R, Brandstetter H, Hirsch A, Ducho C (2021)

ChemMedChemDOI: 10.1002/cmdc.202000994

Inhibitors of Pseudomonas aeruginosa virulence factor LasB

Kaya C, Konstantinovic J, Voos K, Walter I, Kany A, Yahiaoui S, Ducho C, Haupenthal J, Hartmann R, Hirsch A (2021)

Patent (EP20192608.6)

Expanding the Scope of Detectable Microbial Natural Products by Complementary Analytical Methods and Cultivation Systems

Bader C, Haack P, Panter F, Krug D, Müller R (2021)

Journal of natural products 84 (2): 268-277DOI: 10.1021/acs.jnatprod.0c00942

Identification of a 1-deoxy-D-xylulose-5-phosphate synthase (DXS) mutant with improved crystallographic properties

Gierse R, Reddem E, Alhayek A, Baitinger D, Hamid Z, Jakobi H, Laber B, Lange G, Hirsch A, Groves (2021)

Biochemical and Biophysical Research Communications 539DOI: 10.1016/j.bbrc.2020.12.069

Kibdelosporangium persicum sp. nov., a new member of the Actinomycetes from a hot desert in Iran

Safaei N, Nouioui I, Mast Y, Zaburannyi N, Rohde M, Schumann P, Müller R, Wink J (2021)

Int. J. Syst. Evol. Microbiol. 71 (2)DOI: 10.1099/ijsem.0.004625