Publications
Publication Highlights
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Publication database
2022
Induction of Liver Size Reduction in Zebrafish Larvae by the Emerging Synthetic Cannabinoid 4F-MDMB-BINACA and Its Impact on Drug Metabolism
Park Y, Dahlem C, Meyer M, Kiemer A, Müller R, Herrmann J (2022)
Molecules (Basel, Switzerland) 27 (4)DOI: 10.3390/molecules27041290
An Outer Membrane Vesicle-Based Permeation Assay (OMPA) for Assessing Bacterial Bioavailability
Richter R, Kamal M, Koch M, Niebuur B, Huber A, Goes A, Volz C, Vergalli J, Kraus T, Müller R, …, Pagès J, Lehr C (2022)
Advanced healthcare materials 11 (5)DOI: 10.1002/adhm.202101180
N-Aryl Mercaptopropionamides as Broad-Spectrum Inhibitors of Metallo-β-Lactamases
Kaya C, Konstantinovic J, Kany A, Andreas A, Kramer J, Brunst S, Weizel L, Rotter M, Frank D, Yahiaoui S, …, Wichelhaus T, Hirsch A (2022)
Journal of medicinal chemistry 65 (5): 3913-3922DOI: 10.1021/acs.jmedchem.1c01755
Myxobacteria of the Cystobacterineae Suborder Are Producers of New Vitamin K2 Derived Myxoquinones
Panter F, Popoff A, Garcia R, Krug D, Müller R (2022)
Microorganisms 10 (3)DOI: 10.3390/microorganisms10030534
PLSDB: advancing a comprehensive database of bacterial plasmids
Schmartz G, Hartung A, Hirsch P, Kern F, Fehlmann T, Müller R, Keller A (2022)
Nucleic Acids Res 50 (D1): 273-DOI: 10.1093/nar/gkab1111
Metabolic profiling of S-praziquantel: Structure elucidation using the crystalline sponge method in combination with mass spectrometry and nuclear magnetic resonance
Rosenberger L, Jenniches J, Essen C, Khutia A, Kühn C, Marx A, Georgi K, Hirsch A, Hartmann R, Badolo L (2022)
Drug metabolism and disposition: the biological fate of chemicalsDOI: 10.1124/dmd.121.000663
Novel 2,4-disubstituted quinazoline analogs as antibacterial agents with improved cytotoxicity profile: Modification of the benzenoid part
Megahed S, Rasheed S, Herrmann J, El-Hossary E, El-Shabrawy Y, Abadi A, Engel M, Müller R, Abdel-Halim M, Hamed M (2022)
Bioorg Med Chem Lett 59DOI: 10.1016/j.bmcl.2022.128531
New Deoxyenhygrolides from Plesiocystis pacifica Provide Insights into Butenolide Core Biosynthesis
Hug J, Kjaerulff L, Garcia R, Müller R (2022)
Marine drugs 20 (1)DOI: 10.3390/md20010072
Sandacrabins - Structurally Unique Antiviral RNA Polymerase Inhibitors from a Rare Myxobacterium
Bader C, Panter F, Garcia R, Tchesnokov E, Haid S, Walt C, Spröer C, Kiefer A, Götte M, Overmann J, Pietschmann T, Müller R (2022)
Chem. Eur. J. 28 (10)DOI: 10.1002/chem.202104484
Inhibition of Collagenase Q1 of Bacillus cereus as a Novel Antivirulence Strategy for the Treatment of Skin‐Wound Infections
Alhayek A, Khan E, Schönauer E, Däinghaus T, Shafiei R, Voos K, Han M, Ducho C, Posselt G, Wessler S, …, del Campo A, Hirsch A (2022)
Adv. Therap.DOI: 10.1002/adtp.202100222
Bacteriomimetic Liposomes Improve Antibiotic Activity of a Novel Energy-Coupling Factor Transporter Inhibitor
Drost M, Diamanti E, Fuhrmann K, Goes A, Shams A, Haupenthal J, Koch M, Hirsch A, Fuhrmann G (2022)
Pharmaceutics 14 (1)DOI: 10.3390/pharmaceutics14010004
Biotechnological production optimization of argyrins - a potent immunomodulatory natural product class
Pogorevc D, Müller R (2022)
Microbial Biotechnology 15 (1): 353-369DOI: 10.1111/1751-7915.13959
2021
Towards the sustainable discovery and development of new antibiotics
Miethke M, Pieroni M, Weber T, Brönstrup M, Hammann P, Halby L, Arimondo P, Glaser P, Aigle B, Bode H, …, Moser H, Müller R (2021)
Nat Rev Chem: 1-24DOI: 10.1038/s41570-021-00313-1
Improved broad-spectrum antibiotics against Gram-negative pathogens via darobactin biosynthetic pathway engineering
Groß S, Panter F, Pogorevc D, Seyfert C, Deckarm S, Bader C, Herrmann J, Müller R (2021)
Chem. Sci. 12 (35): 11882-11893DOI: 10.1039/d1sc02725e
In vivo and in vitro reconstitution of unique key steps in cystobactamid antibiotic biosynthesis
Groß S, Schnell B, Haack P, Auerbach D, Müller R (2021)
Nat Commun 12 (1)DOI: 10.1038/s41467-021-21848-3
The Sandarazols are Cryptic and Structurally Unique Plasmid-Encoded Toxins from a Rare Myxobacterium*
Panter F, Bader C, Müller R (2021)
Angewandte Chemie (International ed. in English) 60 (15): 8081-8088DOI: 10.1002/anie.202014671
Targeting the IspD Enzyme in the MEP Pathway: Identification of a Novel Fragment Class
Diamanti E, Hamed M, Lacour A, Bravo P, Illarionov B, Fischer M, Rottmann M, Witschel M, Hirsch A (2021)
ChemMedChemDOI: 10.1002/cmdc.202100679
Substrate-Inspired Fragment Merging and Growing Affords Efficacious LasB Inhibitors
Kaya C, Walter I, Yahiaoui S, Sikandar A, Alhayek A, Konstantinovic J, Kany A, Haupenthal J, Köhnke J, Hartmann R, Hirsch A (2021)
Angewandte Chemie (International ed. in English)DOI: 10.1002/anie.202112295
Targeting the energy-coupling factor (ECF) transporters: identification of new tool compounds
Diamanti E, Setyawati I, Bousis S, Souza P, mojas l, Swier l, Haupenthal J, Gibson P, Volz C, stanek w, …, slotboom d, Hirsch A (2021)
ChemRxivDOI: 10.26434/chemrxiv-2021-xq08b-v2
Redesigning of the cap conformation and symmetry of the diphenylethyne core to yield highly potent pan-genotypic NS5A inhibitors with high potency and high resistance barrier
Abdallah M, Hamed M, Frakolaki E, Katsamakas S, Vassilaki N, Bartenschlager R, Zoidis G, Hirsch A, Abdel-Halim M, Abadi A (2021)
European journal of medicinal chemistryDOI: 10.1016/j.ejmech.2021.114034
Unveiling Adatoms in On-Surface Reactions: Combining Scanning Probe Microscopy with van't Hoff Plots
Moreno-López J, Pérez Paz A, Gottardi S, Solianyk L, Li J, Monjas L, Hirsch A, Mowbray D, Stöhr M (2021)
The journal of physical chemistry. C, Nanomaterials and interfaces 125 (18): 9847-9854DOI: 10.1021/acs.jpcc.1c03134
An efficient way to screen inhibitors of energy-coupling factor (ECF) transporters in bacteria uptake assay
Bousis S, Winkler S, Haupenthal J, Fulco F, Diamanti E, Hirsch A (2021)
ChemRxivDOI: 10.26434/chemrxiv-2021-b50gj
Genome-Guided Discovery of the First Myxobacterial Biarylitide Myxarylin Reveals Distinct C-N Biaryl Crosslinking in RiPP Biosynthesis
Hug J, Frank N, Walt C, Šenica P, Panter F, Müller R (2021)
Molecules 26 (24)DOI: 10.3390/molecules26247483
Structure of Escherichia coli cytochrome bd-II type oxidase with bound aurachin D
Grauel A, Kägi J, Rasmussen T, Makarchuk I, Oppermann S, Moumbock A, Wohlwend D, Müller R, Melin F, Günther S, …, Böttcher B, Friedrich T (2021)
Nat Commun 12 (1)DOI: 10.1038/s41467-021-26835-2
1st Spring Virtual Meeting on Medicinal Chemistry
Sousa M, Marques M, Faustino M (2021)
Chemistry Proceedings 4 (1)DOI: 10.3390/chemproc2021004001
Structure and Biosynthesis of Myxofacyclines: Unique Myxobacterial Polyketides Featuring Varing and Rare Heterocycles *
Popoff A, Hug J, Walesch S, Garcia R, Keller L, Müller R (2021)
Chem. Eur. J. 27 (67): 16654-16661DOI: 10.1002/chem.202103095
The natural product vioprolide A exerts anti-inflammatory actions through inhibition of its cellular target NOP14 and downregulation of importin-dependent NF-ĸB p65 nuclear translocation
Burgers L, Luong B, Li Y, Fabritius M, Michalakis S, Reichel C, Müller R, Fürst R (2021)
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 144DOI: 10.1016/j.biopha.2021.112255
Distinct Patterns of Blood Cytokines Beyond a Cytokine Storm Predict Mortality in COVID-19
Herr C, Mang S, Mozafari B, Guenther K, Speer T, Seibert M, Srikakulam S, Beisswenger C, Ritzmann F, Keller A, …, Lepper P, Bals R (2021)
Journal of inflammation research 14: 4651-4667DOI: 10.2147/JIR.S320685
Design, synthesis, and biological evaluation of novel benzimidazole derivatives as sphingosine kinase 1 inhibitor
Khairat S, Omar M, Ragab F, Roy S, Turab Naqvi A, Abdelsamie A, Hirsch A, Galal S, Hassan M, El Diwani H (2021)
Archiv der Pharmazie 354 (9)DOI: 10.1002/ardp.202100080
Physiologically Based Pharmacokinetic/Pharmacodynamic Model for the Treatment of Dengue Infections Applied to the Broad Spectrum Antiviral Soraphen A
Rox K, Heyner M, Krull J, Harmrolfs K, Rinne V, Hokkanen J, Perez Vilaro G, Díez J, Müller R, Kröger A, Sugiyama Y, Brönstrup M (2021)
ACS Pharmacol. Transl. Sci.DOI: 10.1021/acsptsci.1c00078
Identification of N,N-arylalkyl-picolinamide derivatives targeting the RNA-binding protein HuR, by combining biophysical fragment-screening and molecular hybridization
Della Volpe S, Linciano P, Listro R, Tumminelli E, Amadio M, Bonomo I, Elgaher W, Adam S, Hirsch A, Boeckler F, …, Rossi D, Collina S (2021)
Bioorganic chemistry 116DOI: 10.1016/j.bioorg.2021.105305
Expanding the Myxochelin Natural Product Family by Nicotinic Acid Containing Congeners
Frank N, Széles M, Akone S, Rasheed S, Hüttel S, Frewert S, Hamed M, Herrmann J, Schuler S, Hirsch A, Müller R (2021)
Molecules 26 (16)DOI: 10.3390/molecules26164929
N-Aryl mercaptoacetamides as potential multi-target inhibitors of metallo-β-lactamases (MBLs) and the virulence factor LasB from Pseudomonas aeruginosa
Yahiaoui S, Voos K, Haupenthal J, Wichelhaus T, Frank D, Weizel L, Rotter M, Brunst S, Kramer J, Proschak E, Ducho C, Hirsch A (2021)
RSC Med. Chem.DOI: 10.1039/D1MD00187F
Crystalline sponge affinity screening: A fast tool for soaking condition optimization without the need of X-ray diffraction analysis
Rosenberger L, Essen C, Khutia A, Kühn C, Georgi K, Hirsch A, Hartmann R, Badolo L (2021)
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 164DOI: 10.1016/j.ejps.2021.105884
Non-Carbohydrate Glycomimetics as Inhibitors of Calcium(II)-Binding Lectins
Kuhaudomlarp S, Siebs E, Shanina E, Topin J, Joachim I, da Silva Figueiredo Celestino Gomes P, Varrot A, Rognan D, Rademacher C, Imberty A, Titz A (2021)
Angew. Chem. Int. Ed. 60 (15): 8104-8114DOI: 10.1002/anie.202013217
The exo-β-N-acetylmuramidase NamZ from Bacillus subtilis is the founding member of a family of exo-lytic peptidoglycan hexosaminidases
Müller M, Calvert M, Hottmann I, Kluj R, Teufel T, Balbuchta K, Engelbrecht A, Selim K, Xu Q, Borisova M, Titz A, Mayer C (2021)
The Journal of biological chemistry 296DOI: 10.1016/j.jbc.2021.100519
Sesbanimide R, a Novel Cytotoxic Polyketide Produced by Magnetotactic Bacteria
Awal R, Haack P, Bader C, Riese C, Schüler D, Müller R (2021)
mBio 12 (3)DOI: 10.1128/mBio.00591-21
Drug delivery to the inflamed intestinal mucosa- targeting technologies and human cell culture models for better therapies of IBD
Olga H, Shetab Boushehri Maryam A, Shalaby Karim S, Brigitta L, Alf L, Claus-Michael L (2021)
Advanced Drug Delivery ReviewsDOI: 10.1016/j.addr.2021.113828
Development and evaluation of a quality control system based on transdermal electrical resistance for skin barrier function in vitro
Knoth K, Zäh R, Veldung B, Burgio D, Wiegand B, Smola H, Bock U, Lehr C, Hittinger M, Groß H (2021)
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)DOI: 10.1111/srt.12998
Second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane
Zamprogno P, Wüthrich S, Achenbach S, Thoma G, Stucki J, Hobi N, Schneider-Daum N, Lehr C, Huwer H, Geiser T, Schmid R, Guenat O (2021)
Communications Biology 4 (1)DOI: 10.1038/s42003-021-01695-0
Spray-dried lactose-leucine microparticles for pulmonary delivery of antimycobacterial nanopharmaceuticals
Thiyagarajan D, Huck B, Nothdurft B, Koch M, Rudolph D, Rutschmann M, Feldmann C, Hozsa C, Furch M, Besecke K, …, Loretz B, Lehr C (2021)
Drug delivery and translational research 11 (4): 1766-1778DOI: 10.1007/s13346-021-01011-7
Microbiota and cancer: In vitro and in vivo models to evaluate nanomedicines
Ladaycia A, Loretz B, Passirani C, Lehr C, Lepeltier E (2021)
Advanced Drug Delivery Reviews 170: 44-70DOI: 10.1016/j.addr.2020.12.015
Fucosylated lipid nanocarriers loaded with antibiotics efficiently inhibit mycobacterial propagation in human myeloid cells
Durán V, Grabski E, Hozsa C, Becker J, Yasar H, Monteiro J, Costa B, Koller N, Lueder Y, Wiegmann B, …, Graalmann T, Kalinke U (2021)
Journal of controlled release : official journal of the Controlled Release Society 334: 201-212DOI: 10.1016/j.jconrel.2021.04.012
A Custom-Made Device for Reproducibly Depositing Pre-metered Doses of Nebulized Drugs on Pulmonary Cells in vitro
Horstmann J, Thorn C, Carius P, Graef F, Murgia X, Souza Carvalho-Wodarz C, Lehr C (2021)
Frontiers in Bioengineering and Biotechnology 9DOI: 10.3389/fbioe.2021.643491
Formulation and evaluation of transdermal nanogel for delivery of artemether
Nnamani P, Ugwu A, Nnadi O, Kenechukwu F, Ofokansi K, Attama A, Lehr C (2021)
Drug delivery and translational research 11 (4): 1655-1674DOI: 10.1007/s13346-021-00951-4
Surfactant-Free Glibenclamide Nanoparticles: Formulation, Characterization and Evaluation of Interactions with Biological Barriers
Arrua E, Hartwig O, Ho D, Loretz B, Murgia X, Salomon C, Lehr C (2021)
Pharmaceutical research 38 (6): 1081-1092DOI: 10.1007/s11095-021-03056-2
Testing of aerosolized ciprofloxacin nanocarriers on cystic fibrosis airway cells infected with P. aeruginosa biofilms
Juntke J, Murgia X, Günday Türeli N, Türeli A, Thorn C, Schneider M, Schneider-Daum N, Souza Carvalho-Wodarz C, Lehr C (2021)
Drug delivery and translational research 11 (4): 1752-1765DOI: 10.1007/s13346-021-01002-8
Tobramycin Liquid Crystal Nanoparticles Eradicate Cystic Fibrosis-Related Pseudomonas aeruginosa Biofilms
Thorn C, Carvalho-Wodarz C, Horstmann J, Lehr C, Prestidge C, Thomas N (2021)
Small (Weinheim an der Bergstrasse, Germany) 17 (24)DOI: 10.1002/smll.202100531
Decoding (patho-)physiology of the lung by advanced in vitro models for developing novel anti-infectives therapies
Montefusco-Pereira C, Carvalho-Wodarz C, Seeger J, Kloft C, Michelet R, Lehr C (2021)
Drug Discovery Today 26 (1): 148-163DOI: 10.1016/j.drudis.2020.10.016
Analysis and Optimization of Two Film-Coated Tablet Production Processes by Computer Simulation: A Case Study
Hering S, Schäuble N, Buck T, Loretz B, Rillmann T, Stieneker F, Lehr C (2021)
Processes 9 (1)DOI: 10.3390/pr9010067
A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms
Schütz C, Ho D, Hamed M, Abdelsamie A, Röhrig T, Herr C, Kany A, Rox K, Schmelz S, Siebenbürger L, …, Lehr C, Empting M (2021)
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 8 (12)DOI: 10.1002/advs.202004369
Drug delivery for fighting infectious diseases: a global perspective
Loretz B, Oh Y, Hudson S, Gu Z, Lehr C (2021)
Drug delivery and translational research 11 (4): 1316-1322DOI: 10.1007/s13346-021-01009-1
A pulmonary mucus surrogate for investigating antibiotic permeation and activity against Pseudomonas aeruginosa biofilms
Frisch S, Boese A, Huck B, Horstmann J, Ho D, Schwarzkopf K, Murgia X, Loretz B, Souza Carvalho-Wodarz C, Lehr C (2021)
The Journal of antimicrobial chemotherapy 76 (6): 1472-1479DOI: 10.1093/jac/dkab068
Extracellular vesicles as antigen carriers for novel vaccination avenues
Mehanny M, Lehr C, Fuhrmann G (2021)
Advanced Drug Delivery Reviews 173: 164-180DOI: 10.1016/j.addr.2021.03.016
Extracellular vesicles as novel assay tools to study cellular interactions of anti-infective compounds - A perspective
Richter R, Lehr C (2021)
Advanced Drug Delivery Reviews 173: 492-503DOI: 10.1016/j.addr.2021.04.010
Disease Models: Lung Models for Testing Drugs Against Inflammation and Infection
Carius P, Horstmann J, Souza Carvalho-Wodarz C, Lehr C (2021)
Handbook of experimental pharmacology 265: 157-186DOI: 10.1007/164_2020_366
Eap-functionalized liposomes as a bioinspired delivery system for oral delivery of colistin to treat intracellular Salmonella infection
Menina S (2021)
Book
Zebrafish: An Attractive Model to Study Staphylococcus aureus Infection and Its Use as a Drug Discovery Tool
Rasheed S, Fries F, Müller R, Herrmann J (2021)
Pharmaceuticals 14 (6)DOI: 10.3390/ph14060594
“Clicking“ fragment leads to novel dual-binding cholinesterase inhibitors
Moleda Z, Zawadzka A, Czarnocki Z, Monjas L, Hirsch A, Budzianowski A, Maurin J (2021)
Bioorg Med ChemDOI: 10.1016/j.bmc.2021.116269
Structure and biosynthesis of sorangipyranone - a new γ-dihydropyrone from the myxobacterial strain MSr12020
Okoth D, Hug J, Mándi A, Kurtán T, Garcia R, Müller R (2021)
Journal of Industrial Microbiology & Biotechnology 48 (3-4)DOI: 10.1093/jimb/kuab029
Front Cover: Phosphonate as a Stable Zinc‐Binding Group for “Pathoblocker” Inhibitors of Clostridial Collagenase H (ColH) (ChemMedChem 8/2021)
Voos K, Schönauer E, Alhayek A, Haupenthal J, Andreas A, Müller R, Hartmann R, Brandstetter H, Hirsch A, Ducho C (2021)
ChemMedChem 16 (8): 1198-1198DOI: 10.1002/cmdc.202100229
Hit-optimization using target-directed dynamic combinatorial chemistry: Development of inhibitors of the anti-infective target 1-deoxy-D-xylulose-5-phosphate synthase
Jumde R, Guadigni M, Gierse R, Alhayek A, Di Zhu, Hamid Z, Johannsen S, Elgaher W, Neusens P, Nehls C, …, Reiling N, Hirsch A (2021)
Chemical ScienceDOI: 10.1039/D1SC00330E
miRMaster 2.0: multi-species non-coding RNA sequencing analyses at scale
Fehlmann T, Kern F, Laham O, Backes C, Solomon J, Hirsch P, Volz C, Müller R, Keller A (2021)
Nucleic Acids ResDOI: 10.1093/nar/gkab268
Search for the Active Ingredients from a 2-Aminothiazole DMSO Stock Solution with Antimalarial Activity
Ropponen H, Bader C, Diamanti E, Illarionov B, Rottmann M, Fischer M, Witschel M, Müller R, Hirsch A (2021)
ChemMedChem 16 (13): 2089-2093DOI: 10.1002/cmdc.202100067
Synergizing the potential of bacterial genomics and metabolomics to find novel antibiotics
Panter F, Bader C, Müller R (2021)
Chem. Sci. 12 (17): 5994-6010DOI: 10.1039/d0sc06919a
Targeting cellular fatty acid synthesis limits T helper and innate lymphoid cell function during intestinal inflammation and infection
Mamareli P, Kruse F, Lu C, Guderian M, Floess S, Rox K, Allan D, Carlyle J, Brönstrup M, Müller R, …, Sparwasser T, Lochner M (2021)
Mucosal Immunol. 14 (1): 164-176DOI: 10.1038/s41385-020-0285-7
Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis
Almeida L, Dhillon-LaBrooy A, Castro C, Adossa N, Carriche G, Guderian M, Lippens S, Dennerlein S, Hesse C, Lambrecht B, …, Moita L, Sparwasser T (2021)
Immunity 54 (1): 68-83DOI: 10.1016/j.immuni.2020.11.001
Stimulation of Probiotic Bacteria Induces Release of Membrane Vesicles with Augmented Anti-inflammatory Activity
Müller L, Kuhn T, Koch M, Fuhrmann G (2021)
ACS Appl. Bio Mater.DOI: 10.1021/acsabm.0c01136
Mastering the Gram-Negative Bacterial Barrier - Chemical Approaches to Increase Bacterial Bioavailability of Antibiotics
Ropponen H, Richter R, Hirsch A, Lehr C (2021)
Advanced Drug Delivery ReviewsDOI: 10.1016/j.addr.2021.02.014
Assessment of the rules related to gaining activity against Gram-negative bacteria
Ropponen H, Diamanti E, Siemens A, Illarionov B, Haupenthal J, Fischer M, Rottmann M, Witschel M, Hirsch A (2021)
RSC Med. Chem.DOI: 10.1039/D0MD00409J
Natural products in drug discovery: advances and opportunities
Atanasov A, Zotchev S, Dirsch V, Supuran C (2021)
Nature reviews. Drug discovery 20 (3): 200-216DOI: 10.1038/s41573-020-00114-z
Enhancing glycan stability via site-selective fluorination: modulating substrate orientation by molecular design
Axer A, Jumde R, Adam S, Faust A, Schäfers M, Fobker M, Koehnke J, Hirsch A, Gilmour R (2021)
Chem. Sci. 12 (4): 1286-1294DOI: 10.1039/D0SC04297H
Phosphonate as Stable Zinc-binding Group for Inhibitors of Clostridial Collagenase H (ColH) as Pathoblocker Agents
Voos K, Schönauer E, Alhayek A, Haupenthal J, Andreas A, Müller R, Hartmann R, Brandstetter H, Hirsch A, Ducho C (2021)
ChemMedChemDOI: 10.1002/cmdc.202000994
Inhibitors of Pseudomonas aeruginosa virulence factor LasB
Kaya C, Konstantinovic J, Voos K, Walter I, Kany A, Yahiaoui S, Ducho C, Haupenthal J, Hartmann R, Hirsch A (2021)
Patent (EP20192608.6)
Expanding the Scope of Detectable Microbial Natural Products by Complementary Analytical Methods and Cultivation Systems
Bader C, Haack P, Panter F, Krug D, Müller R (2021)
Journal of natural products 84 (2): 268-277DOI: 10.1021/acs.jnatprod.0c00942
Identification of a 1-deoxy-D-xylulose-5-phosphate synthase (DXS) mutant with improved crystallographic properties
Gierse R, Reddem E, Alhayek A, Baitinger D, Hamid Z, Jakobi H, Laber B, Lange G, Hirsch A, Groves (2021)
Biochemical and Biophysical Research Communications 539DOI: 10.1016/j.bbrc.2020.12.069
Kibdelosporangium persicum sp. nov., a new member of the Actinomycetes from a hot desert in Iran
Safaei N, Nouioui I, Mast Y, Zaburannyi N, Rohde M, Schumann P, Müller R, Wink J (2021)
Int. J. Syst. Evol. Microbiol. 71 (2)DOI: 10.1099/ijsem.0.004625