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Total synthesis of (-)-doliculide, structure-activity relationship studies and its binding to F-actin
Publikation
Matcha K,
Madduri A,
Roy S,
Ziegler S,
Waldmann H,
Hirsch A,
Minnaard A
(2012)
ChemBioChem, 13, 17, 2537-48, 10.1002/cbic.201200512, 23129522
ChemBioChem, 13, 17, 2537-48, 10.1002/cbic.201200512, 23129522
'Triazole bridge': disulfide-bond replacement by ruthenium-catalyzed formation of 1,5-disubstituted 1,2,3-triazoles
Publikation
Empting M,
Avrutina O,
Meusinger R,
Fabritz S,
Reinwarth M,
Biesalski M,
Voigt S,
Buntkowsky G,
Kolmar H
(2011)
Angewandte Chemie (International ed. in English), 50, 22, 5207-11, 10.1002/anie.201008142, 21544910
Angewandte Chemie (International ed. in English), 50, 22, 5207-11, 10.1002/anie.201008142, 21544910
Towards click bioconjugations on cube-octameric silsesquioxane scaffolds
Publikation
Fabritz S,
Heyl D,
Bagutski V,
Empting M,
Rikowski E,
Frauendorf H,
Balog I,
Fessner W,
Schneider J,
Avrutina O,
Kolmar H
(2010)
Org. Biomol. Chem., 8, 9, 2212-8, 10.1039/b923393h, 20401398
Org. Biomol. Chem., 8, 9, 2212-8, 10.1039/b923393h, 20401398
Application of copper(I) catalyzed azide-alkyne 3+2 cycloaddition to the synthesis of template-assembled multivalent peptide conjugates
Publikation
Avrutina O,
Empting M,
Fabritz S,
Daneschdar M,
Frauendorf H,
Diederichsen U,
Kolmar H
(2009)
Org. Biomol. Chem., 7, 20, 4177-85, 10.1039/b908261a, 19795056
Org. Biomol. Chem., 7, 20, 4177-85, 10.1039/b908261a, 19795056
SYNTHESIS, ANTI-BRONCHOCONSTRICTIVE, AND ANTIBACTERIAL ACTIVITIES OF SOME NEW 8- SUBSTITUTED-1,3-DIMETHYLXANTHINE DERIVATIVES
Publikation
Elgaher W,
Hayallah A,
Salem O,
Abdel Alim A
(2009)
Bulletin of Pharmaceutical Sciences. Assiut, 32, 1, 153-187, 10.21608/BFSA.2009.63355
Bulletin of Pharmaceutical Sciences. Assiut, 32, 1, 153-187, 10.21608/BFSA.2009.63355
Bioconjugates to specifically render inhibitors water-soluble
Publikation
Hirsch A,
Diederich F,
Antonietti M,
Börner H
(2009)
Soft Matter, 6, 1, 88-91, 10.1039/B915928B
Soft Matter, 6, 1, 88-91, 10.1039/B915928B
Inhibitors of the kinase IspE: structure-activity relationships and co-crystal structure analysis
Publikation
Hirsch A,
Alphey M,
Lauw S,
Seet M,
Barandun L,
Eisenreich W,
Rohdich F,
Hunter W,
Bacher A,
Diederich F
(2008)
Organic & biomolecular chemistry, 6, 15, 2719-30, 10.1039/b804375b, 18633530
Organic & biomolecular chemistry, 6, 15, 2719-30, 10.1039/b804375b, 18633530
Synthesis and characterization of cytidine derivatives that inhibit the kinase IspE of the non-mevalonate pathway for isoprenoid biosynthesis
Publikation
Crane C,
Hirsch A,
Alphey M,
Sgraja T,
Lauw S,
Illarionova V,
Rohdich F,
Eisenreich W,
Hunter W,
Bacher A,
Diederich F
(2008)
ChemMedChem, 3, 1, 91-101, 10.1002/cmdc.200700208, 18033714
ChemMedChem, 3, 1, 91-101, 10.1002/cmdc.200700208, 18033714
Phosphate recognition in structural biology
Publikation
Hirsch A,
Fischer F,
Diederich F
(2007)
Angewandte Chemie (International ed. in English), 46, 3, 338-52, 10.1002/anie.200603420, 17154432
Angewandte Chemie (International ed. in English), 46, 3, 338-52, 10.1002/anie.200603420, 17154432
Nonphosphate inhibitors of IspE protein, a kinase in the non-mevalonate pathway for isoprenoid biosynthesis and a potential target for antimalarial therapy
Publikation
Hirsch A,
Lauw S,
Gersbach P,
Schweizer W,
Rohdich F,
Eisenreich W,
Bacher A,
Diederich F
(2007)
ChemMedChem, 2, 6, 806-10, 10.1002/cmdc.200700014, 17361977
ChemMedChem, 2, 6, 806-10, 10.1002/cmdc.200700014, 17361977