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Discovery of the first small-molecule CsrA-RNA interaction inhibitors using biophysical screening technologies
Publikation
Maurer C,
Fruth M,
Empting M,
Avrutina O,
Hossmann J,
Nadmid S,
Gorges J,
Herrmann J,
Kazmaier U,
Dersch P,
Muller R,
Hartmann R
(2016)
Future medicinal chemistry, 8, 9, 931-47, 10.4155/fmc-2016-0033, 27253623
Future medicinal chemistry, 8, 9, 931-47, 10.4155/fmc-2016-0033, 27253623
N -Aryl-3-mercaptosuccinimides as Antivirulence Agents Targeting Pseudomonas aeruginosa Elastase and Clostridium Collagenases
Publikation
Konstantinovic J,
Yahiaoui S,
Alhayek A,
Haupenthal J,
Schönauer E,
Andreas A,
Kany A,
Müller R,
Koehnke J,
Berger F,
Bischoff M,
Hartmann R,
Brandstetter H,
Hirsch A
(2020)
J. Med. Chem., 63, 15, 8359-8368, 10.1021/acs.jmedchem.0c00584
J. Med. Chem., 63, 15, 8359-8368, 10.1021/acs.jmedchem.0c00584
Adaptation of a Bacterial Multidrug Resistance System Revealed by the Structure and Function of AlbA
Publikation
Sikandar A,
Cirnski K,
Testolin G,
Volz C,
Brönstrup M,
Kalinina O,
Müller R,
Koehnke J
(2018)
J. Am. Chem. Soc., 140, 48, 16641-16649, 10.1021/jacs.8b08895, 30422653
J. Am. Chem. Soc., 140, 48, 16641-16649, 10.1021/jacs.8b08895, 30422653
Bacterial RNAP Inhibitors: Synthesis and Evaluation of Prodrugs of Aryl‐ureidothiophene‐carboxylic acids
Publikation
Ruthenbeck A,
Elgaher W,
Haupenthal J,
Hartmann R,
Meier C
(2017)
ChemistrySelect, 2, 35, 11899-11905, 10.1002/slct.201702574
ChemistrySelect, 2, 35, 11899-11905, 10.1002/slct.201702574
Evolution of novel antibiotic Scaffolds targeting the nucleic acid machineries RNA polymerase, DNA gyrase, and topoisomerase IV
Publikation
Elgaher W
(2016)
Thesis, 10.22028/D291-23193
Thesis, 10.22028/D291-23193
Surface plasmon resonance--more than a screening technology: insights in the binding mode of σ70:core RNAP inhibitors
Publikation
Hüsecken K,
Hinsberger S,
Elgaher W,
Haupenthal J,
Hartmann R
(2014)
Future medicinal chemistry, 6, 14, 1551-65, 10.4155/fmc.14.105, 25367390
Future medicinal chemistry, 6, 14, 1551-65, 10.4155/fmc.14.105, 25367390
New Theophylline Derivatives
Publikation
Elgaher W
(2011)
Book
Book
Design and synthesis of some new theophylline derivatives with bronchodilator and antibacterial activities
Publikation
Hayallah A,
Elgaher W,
Salem O,
Alim A
(2011)
Arch Pharm Res, 34, 1, 3-21, 10.1007/s12272-011-0101-8, 21468910
Arch Pharm Res, 34, 1, 3-21, 10.1007/s12272-011-0101-8, 21468910
Novel and Extremely Sensitive NiAl2O4-NiO Nanostructures on an ITO Sensing Electrode for Enhanced Detection of Ascorbic Acid
Publikation
Hammami A,
Bardaoui A,
Eissa S,
Elgaher W,
Chtourou R,
Messaoud O
(2024)
Molecules (Basel, Switzerland), 29, 12, 10.3390/molecules29122837, 38930902
Molecules (Basel, Switzerland), 29, 12, 10.3390/molecules29122837, 38930902
Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways
Publikation
Kurmasheva N,
Said A,
Wong B,
Kinderman P,
Han X,
Rahimic A,
Kress A,
Carter-Timofte M,
Holm E,
van der Horst D,
Kollmann C,
Liu Z,
Wang C,
Hoang H,
Kovalenko E,
Chrysopoulou M,
Twayana K,
Ottosen R,
Svenningsen E,
Begnini F,
Kiib A,
Kromm F,
Weiss H,
Di Carlo D,
Muscolini M,
Higgins M,
van der Heijden M,
Arulanandam R,
Bardoul A,
Tong T,
Ozsvar A,
Hou W,
Schack V,
Holm C,
Zheng Y,
Ruzek M,
Kalucka J,
La Vega L,
Elgaher W,
Korshoej A,
Lin R,
Hiscott J,
Poulsen T,
O'Neill L,
Roy D,
Rinschen M,
van Montfoort N,
Diallo J,
Farin H,
Alain T,
Olagnier D
(2024)
Nat Commun, 15, 1, 10.1038/s41467-024-48422-x, 38750019
Nat Commun, 15, 1, 10.1038/s41467-024-48422-x, 38750019