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for Pharmaceutical Research Saarland (HIPS) have now discovered that the approved Parkinson's drug tolcapone is able to specifically inhibit the activity of LecA. This finding allows the research [...] starting point for the development of…
BIOBARRIERS 2021
Event
Date:
Sep 7th 2021 09:00
- Sep 8th 2021 18:00
Location: Online
Location: Online
. Now we are cordially inviting you to virtual BioBarriers 2021 – an online conference focused on drug delivery in the context of infection research. The interfaces of the outer epithelia (skin, GI, and lungs) as either target tissue or barrier for…
HIPS Ahoy!
News
is precisely these molecules that will subsequently serve as the basis for the development of new drugs to treat infections. The MYXO-MAT-3000 demonstrates how the search for such active ingredients [...] analysis area, where lasers, fog effects,…
Specific drugs are currently available for only a few viruses. There is no such thing as a broad-spectrum antibiotic [...] , head of the junior research group “Nano Infection Biology” at the HZI. “Our goal is to create a drug-development platform…
Imaging
Page
scanning electron microscopes, this platform allows visualising and characterising micro and nanoscale drug delivery systems, as wells as physiological, biochemical and infective phenomena in in vivo/in vitro [...] patterns, biofilm structures or…
derived from bacteria, show excellent antimicrobial activity, but have long remained out of reach for drug development. The main obstacle was the limited understanding of how these compounds are produced by [...] 132,000 cases of…
typically involves a combination of several antibiotics over many months. Particularly problematic are drug-resistant strains, against which the antibiotics used are only partially effective. New active [...] antibiotics. The results thus suggest…
Dr Alexander Kiefer
Person
research endeavors were centered on the development of anthraquinone-fused enediyne-based antibody-drug conjugates as promising anticancer agents. Upon returning to HIPS in mid-2024 on a DFG Walter Benjamin [...] Groups grant. This enabled…
Read moreNatural products exhibit versatile bioactivities and provide valuable lead structures for drug discovery. Although the total number of characterized natural products increased over the last [...] required for the development of…
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making it the ideal place to connect my research background with cutting-edge synthetic biology for drug discovery.” The scientific goal of his project is to establish a versatile cell-free platform that will make it possible to design, synthesize,…