Katharina Cirnski
About
Katarina Cirnski studied Biotechnology at the Biotechnical Faculty of the University of Ljubljana, Slovenia. She obtained her Master’s degree in 2015. In the following year, she started her work at HIPS as a PhD student.
Her work focuses on Mode of Action (MoA) and Mode of Resistance (MoR) studies of new bioactive compounds supplemented by in vivo toxicity and efficacy evaluation in zebrafish larvae (Danio rerio).
2020
Synthetic and Biological Studies on New Urea and Triazole Containing Cystobactamid Derivatives
Planke T, Cirnski K, Herrmann J, Müller R, Kirschning A (2020)
Chem. Eur. J. 26 (19): 4289-4296DOI: 10.1002/chem.201904073
Cystobactamid 507: Concise Synthesis, Mode of Action, and Optimization toward More Potent Antibiotics
Elgaher W, Hamed M, Baumann S, Herrmann J, Siebenbürger L, Krull J, Cirnski K, Kirschning A, Brönstrup M, Müller R, Hartmann R (2020)
Chem. Eur. J. 26 (32): 7219-7225DOI: 10.1002/chem.202000117
Metabolic Profiling to Determine Bactericidal or Bacteriostatic Effects of New Natural Products using Isothermal Microcalorimetry
Cirnski K, Coetzee J, Herrmann J, Müller R (2020)
Journal of visualized experiments : JoVE (164)DOI: 10.3791/61703
PLGA nanocapsules improve the delivery of clarithromycin to kill intracellular Staphylococcus aureus and Mycobacterium abscessus
Anversa Dimer F, Souza Carvalho-Wodarz C, Goes A, Cirnski K, Herrmann J, Schmitt V, Pätzold L, Abed N, Rossi C, Bischoff M, …, Müller R, Lehr C (2020)
Nanomedicine : nanotechnology, biology, and medicine 24DOI: 10.1016/j.nano.2019.102125
Synthetic studies of cystobactamids as antibiotics and bacterial imaging carriers lead to compounds with high in vivo efficacy
Testolin G, Cirnski K, Rox K, Prochnow H, Fetz V, Grandclaudon C, Mollner T, Baiyoumy A, Ritter A, Leitner C, …, Müller R, Brönstrup M (2020)
Chemical Science 11 (5): 1316-1334DOI: 10.1039/C9SC04769G
2018
Adaptation of a Bacterial Multidrug Resistance System Revealed by the Structure and Function of AlbA
Sikandar A, Cirnski K, Testolin G, Volz C, Brönstrup M, Kalinina O, Müller R, Koehnke J (2018)
J. Am. Chem. Soc. 140 (48): 16641-16649DOI: 10.1021/jacs.8b08895
Concepts and Methods to Access Novel Antibiotics from Actinomycetes
Hug J, Bader C, Remškar M, Cirnski K, Müller R (2018)
Antibiotics 7 (2)DOI: 10.3390/antibiotics7020044