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Unlocking the Antiviral Arsenal: Structure-Guided Optimization of Small-Molecule Inhibitors against RSV and hCoV-229E
Publication
Karhan C,
Sake S,
Gunesch A,
Grethe C,
Hellwinkel B,
Köhler N,
Kiefer A,
Hapko U,
Kany A,
Pietschmann T,
Hirsch A
(2025)
European journal of medicinal chemistry, 10.1016/j.ejmech.2025.117282
European journal of medicinal chemistry, 10.1016/j.ejmech.2025.117282
Search for the Active Ingredients from a 2-Aminothiazole DMSO Stock Solution with Antimalarial Activity
Publication
Ropponen H,
Bader C,
Diamanti E,
Illarionov B,
Rottmann M,
Fischer M,
Witschel M,
Müller R,
Hirsch A
(2021)
ChemMedChem, 16, 13, 2089-2093, 10.1002/cmdc.202100067, 33844432
ChemMedChem, 16, 13, 2089-2093, 10.1002/cmdc.202100067, 33844432
Dipeptidic Phosphonates: Potent Inhibitors of Pseudomonas aeruginosa Elastase B Showing Efficacy in a Murine Keratitis Model
Publication
Kiefer A,
Schütz C,
Englisch C,
Kolling D,
Speicher S,
Kany A,
Shafiei R,
Wadood N,
Aljohmani A,
Wirschem N,
Jumde R,
Klein A,
Sikandar A,
Park Y,
Krasteva-Christ G,
Yildiz D,
Abdelsamie A,
Rox K,
Köhnke J,
Müller R,
Bischoff M,
Haupenthal J,
Hirsch A
(2025)
Adv. Sci., 10.1002/advs.202411807, 39973061
Adv. Sci., 10.1002/advs.202411807, 39973061
Synthesis of New Cyclomarin Derivatives and Their Biological Evaluation towards Mycobacterium Tuberculosis and Plasmodium Falciparum
Publication
Kiefer A,
Bader C,
Held J,
Esser A,
Rybniker J,
Empting M,
Müller R,
Kazmaier U
(2019)
Chem. Eur. J., 25, 37, 8894-8902, 10.1002/chem.201901640, 31012978
Chem. Eur. J., 25, 37, 8894-8902, 10.1002/chem.201901640, 31012978
