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Dual inhibitors of Pseudomonas aeruginosa virulence factors LecA and LasB
Publication
Metelkina O,
Konstantinovic J,
Klein A,
Shafiei R,
Fares M,
Alhayek A,
Yahiaoui S,
Elgaher W,
Haupenthal J,
Titz* A,
Hirsch* A
(2024)
Chem. Sci., 15, 10.1039/D4SC02703E
Chem. Sci., 15, 10.1039/D4SC02703E
Dynamic Combinatorial Chemistry Unveils Nsp10 Inhibitors with Antiviral Potential Against SARS-CoV-2
Publication
Jumde R,
Jézéquel G,
Saramago M,
Frank N,
Adam S,
Cunha M,
Bader C,
Gunesch A,
Köhler N,
Johannsen S,
Bousis S,
Pietschmann T,
Matos R,
Müller R,
Arraiano C,
Hirsch A
(2024)
Chem. - Eur. J., 10.1002/chem.202403390, 39676060
Chem. - Eur. J., 10.1002/chem.202403390, 39676060
Search for the Active Ingredients from a 2-Aminothiazole DMSO Stock Solution with Antimalarial Activity
Publication
Ropponen H,
Bader C,
Diamanti E,
Illarionov B,
Rottmann M,
Fischer M,
Witschel M,
Müller R,
Hirsch A
(2021)
ChemMedChem, 16, 13, 2089-2093, 10.1002/cmdc.202100067, 33844432
ChemMedChem, 16, 13, 2089-2093, 10.1002/cmdc.202100067, 33844432
Dipeptidic Phosphonates: Potent Inhibitors of Pseudomonas aeruginosa Elastase B Showing Efficacy in a Murine Keratitis Model
Publication
Kiefer A,
Schütz C,
Englisch C,
Kolling D,
Speicher S,
Kany A,
Shafiei R,
Wadood N,
Aljohmani A,
Wirschem N,
Jumde R,
Klein A,
Sikandar A,
Park Y,
Krasteva-Christ G,
Yildiz D,
Abdelsamie A,
Rox K,
Köhnke J,
Müller R,
Bischoff M,
Haupenthal J,
Hirsch A
(2025)
Adv. Sci., 10.1002/advs.202411807, 39973061
Adv. Sci., 10.1002/advs.202411807, 39973061
Synthesis of New Cyclomarin Derivatives and Their Biological Evaluation towards Mycobacterium Tuberculosis and Plasmodium Falciparum
Publication
Kiefer A,
Bader C,
Held J,
Esser A,
Rybniker J,
Empting M,
Müller R,
Kazmaier U
(2019)
Chem. Eur. J., 25, 37, 8894-8902, 10.1002/chem.201901640, 31012978
Chem. Eur. J., 25, 37, 8894-8902, 10.1002/chem.201901640, 31012978
