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Targeting extracellular lectins of Pseudomonas aeruginosa with glycomimetic liposomes
Publication
Metelkina O,
Huck B,
O'Connor J,
Koch M,
Manz A,
Lehr C,
Titz A
(2022)
Journal of Materials Chemistry B, 10, 4, 537-548, 10.1039/d1tb02086b, 34985094
Journal of Materials Chemistry B, 10, 4, 537-548, 10.1039/d1tb02086b, 34985094
Nano-in-Microparticles for Aerosol Delivery of Antibiotic-Loaded, Fucose-Derivatized, and Macrophage-Targeted Liposomes to Combat Mycobacterial Infections: In Vitro Deposition, Pulmonary Barrier Interactions, and Targeted Delivery
Publication
Huck B,
Thiyagarajan D,
Bali A,
Boese A,
Besecke K,
Hozsa C,
Gieseler R,
Furch M,
Carvalho-Wodarz C,
Waldow F,
Schwudke D,
Metelkina O,
Titz A,
Huwer H,
Schwarzkopf K,
Hoppstädter J,
Kiemer A,
Koch M,
Loretz B,
Lehr C
(2022)
Advanced healthcare materials, 11, 11, 10.1002/adhm.202102117, 35112802
Advanced healthcare materials, 11, 11, 10.1002/adhm.202102117, 35112802
Genome Mining Guided Identification of the Metallophore Delftichelin A from Delftia deserti
Publication
Kruijff M,
Hiller L,
Birkelbach J,
Decker T,
Götze S,
Kochems R,
Müller R,
Hirsch A,
Beemelmanns C
(2026)
J. Nat. Prod., 89, 4, 1318-1331, 10.1021/acs.jnatprod.6c00213
J. Nat. Prod., 89, 4, 1318-1331, 10.1021/acs.jnatprod.6c00213
Point mutations in the ygiV promoter region lead to cystobactamid resistance and reduced virulence in E. coli
Publication
Müller R,
Risch T,
Kolling D,
Mostert D,
Seedorf T,
Heimann D,
Kohnhäuser D,
Deschner F,
Fries F,
Solga D,
Hilgers J,
Dastbaz J,
Hirsch A,
Brönstrup M,
Kirschning A,
Herrmann J,
Sieber S
(2024)
Book, 10.21203/rs.3.rs-3751821/v1
Book, 10.21203/rs.3.rs-3751821/v1
Development and evaluation of 2,4-disubstituted-5-aryl pyrimidine derivatives as antibacterial agents
Publication
Khalifa H,
Rasheed S,
Haupenthal J,
Herrmann J,
Mandour Y,
Abadi A,
Engel M,
Müller R,
Hirsch A,
Abdel-Halim* M,
Hamed* M
(2024)
Archiv der Pharmazie, 10.1002/ardp.202300656, 38304944
Archiv der Pharmazie, 10.1002/ardp.202300656, 38304944
Inhibitors of the Elastase LasB for the Treatment of Pseudomonas aeruginosa Lung Infections
Publication
Konstantinovic J,
Kany A,
Alhayek A,
Abdelsamie A,
Sikandar A,
Voos K,
Yao Y,
Andreas A,
Shafiei R,
Loretz B,
Schönauer E,
Bals R,
Brandstetter H,
Hartmann R,
Ducho C,
Lehr C,
Beisswenger C,
Müller R,
Rox K,
Haupenthal J,
Hirsch A
(2023)
ACS Cent. Sci., 9, 12, 2205-2215, 10.1021/acscentsci.3c01102, 38161367
ACS Cent. Sci., 9, 12, 2205-2215, 10.1021/acscentsci.3c01102, 38161367
Fighting antibiotic resistance-strategies and (pre)clinical developments to find new antibacterials
Publication
Walesch S,
Birkelbach J,
Jézéquel G,
Haeckl F,
Hegemann J,
Hesterkamp T,
Hirsch A,
Hammann P,
Müller R
(2023)
EMBO reports, 24, 1, 10.15252/embr.202256033, 36533629
EMBO reports, 24, 1, 10.15252/embr.202256033, 36533629
Expanding the Myxochelin Natural Product Family by Nicotinic Acid Containing Congeners
Publication
Frank N,
Széles M,
Akone S,
Rasheed S,
Hüttel S,
Frewert S,
Hamed M,
Herrmann J,
Schuler S,
Hirsch A,
Müller R
(2021)
Molecules, 26, 16, 10.3390/molecules26164929
Molecules, 26, 16, 10.3390/molecules26164929
Protein‐Templated Hit Identification via an Ugi Four‐Component Reaction
Publication
Mancini F,
Unver M,
Elgaher W,
Jumde V,
Alhayek A,
Lukat P,
Herrmann J,
Witte M,
Köck M,
Blankenfeldt W,
Müller R,
Hirsch A
(2020)
Chem. Eur. J., 10.1002/chem.202002250
Chem. Eur. J., 10.1002/chem.202002250