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Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections
Publication
Wagner S,
Sommer R,
Hinsberger S,
Lu C,
Hartmann R,
Empting M,
Titz A
(2016)
Journal of medicinal chemistry, 59, 13, 5929-69, 10.1021/acs.jmedchem.5b01698, 26804741
Journal of medicinal chemistry, 59, 13, 5929-69, 10.1021/acs.jmedchem.5b01698, 26804741
Targeting extracellular lectins of Pseudomonas aeruginosa with glycomimetic liposomes
Publication
Metelkina O,
Huck B,
O'Connor J,
Koch M,
Manz A,
Lehr C,
Titz A
(2022)
Journal of Materials Chemistry B, 10, 4, 537-548, 10.1039/d1tb02086b, 34985094
Journal of Materials Chemistry B, 10, 4, 537-548, 10.1039/d1tb02086b, 34985094
Nano-in-Microparticles for Aerosol Delivery of Antibiotic-Loaded, Fucose-Derivatized, and Macrophage-Targeted Liposomes to Combat Mycobacterial Infections: In Vitro Deposition, Pulmonary Barrier Interactions, and Targeted Delivery
Publication
Huck B,
Thiyagarajan D,
Bali A,
Boese A,
Besecke K,
Hozsa C,
Gieseler R,
Furch M,
Carvalho-Wodarz C,
Waldow F,
Schwudke D,
Metelkina O,
Titz A,
Huwer H,
Schwarzkopf K,
Hoppstädter J,
Kiemer A,
Koch M,
Loretz B,
Lehr C
(2022)
Advanced healthcare materials, 11, 11, 10.1002/adhm.202102117, 35112802
Advanced healthcare materials, 11, 11, 10.1002/adhm.202102117, 35112802
Advanced mutasynthesis studies on the natural α-pyrone antibiotic myxopyronin from Myxococcus fulvus
Publication
Sahner J,
Sucipto H,
Wenzel S,
Groh M,
Hartmann R,
Müller R
(2015)
ChemBioChem, 16, 946-953, 10.1002/cbic.201402666, 25757034
ChemBioChem, 16, 946-953, 10.1002/cbic.201402666, 25757034
Expanding the Myxochelin Natural Product Family by Nicotinic Acid Containing Congeners
Publication
Frank N,
Széles M,
Akone S,
Rasheed S,
Hüttel S,
Frewert S,
Hamed M,
Herrmann J,
Schuler S,
Hirsch A,
Müller R
(2021)
Molecules, 26, 16, 10.3390/molecules26164929
Molecules, 26, 16, 10.3390/molecules26164929
Protein‐Templated Hit Identification via an Ugi Four‐Component Reaction
Publication
Mancini F,
Unver M,
Elgaher W,
Jumde V,
Alhayek A,
Lukat P,
Herrmann J,
Witte M,
Köck M,
Blankenfeldt W,
Müller R,
Hirsch A
(2020)
Chem. Eur. J., 10.1002/chem.202002250
Chem. Eur. J., 10.1002/chem.202002250
Synthesis and Biological Evaluation of Novel 2-Substituted Analogues of (–)-Pentenomycin I
Publication
Zisopoulou S,
Bousis S,
Haupenthal J,
Herrmann J,
Müller R,
Hirsch A,
Komiotis D,
Gallos J,
Stathakis C
(2020)
Synlett, 31, 05, 475-481, 10.1055/s-0039-1690772
Synlett, 31, 05, 475-481, 10.1055/s-0039-1690772
Inhibitors of the Elastase LasB for the Treatment of Pseudomonas aeruginosa Lung Infections
Publication
Konstantinovic J,
Kany A,
Alhayek A,
Abdelsamie A,
Sikandar A,
Voos K,
Yao Y,
Andreas A,
Shafiei R,
Loretz B,
Schönauer E,
Bals R,
Brandstetter H,
Hartmann R,
Ducho C,
Lehr C,
Beisswenger C,
Müller R,
Rox K,
Haupenthal J,
Hirsch A
(2023)
ACS Cent. Sci., 9, 12, 2205-2215, 10.1021/acscentsci.3c01102, 38161367
ACS Cent. Sci., 9, 12, 2205-2215, 10.1021/acscentsci.3c01102, 38161367