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Researchers in HIPS Laboratory

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Searched for "drug". Displaying results 741 to 750 of 761.

Nano-in-Microparticles for Aerosol Delivery of Antibiotic-Loaded, Fucose-Derivatized, and Macrophage-Targeted Liposomes to Combat Mycobacterial Infections: In Vitro Deposition, Pulmonary Barrier Interactions, and Targeted Delivery

Publication
Huck B, Thiyagarajan D, Bali A, Boese A, Besecke K, Hozsa C, Gieseler R, Furch M, Carvalho-Wodarz C, Waldow F, Schwudke D, Metelkina O, Titz A, Huwer H, Schwarzkopf K, Hoppstädter J, Kiemer A, Koch M, Loretz B, Lehr C (2022)
Advanced healthcare materials, 11, 11, 10.1002/adhm.202102117, 35112802

Point mutations in the ygiV promoter region lead to cystobactamid resistance and reduced virulence in E. coli

Publication
Müller R, Risch T, Kolling D, Mostert D, Seedorf T, Heimann D, Kohnhäuser D, Deschner F, Fries F, Solga D, Hilgers J, Dastbaz J, Hirsch A, Brönstrup M, Kirschning A, Herrmann J, Sieber S (2024)
Book, 10.21203/rs.3.rs-3751821/v1

Development and evaluation of 2,4-disubstituted-5-aryl pyrimidine derivatives as antibacterial agents

Publication
Khalifa H, Rasheed S, Haupenthal J, Herrmann J, Mandour Y, Abadi A, Engel M, Müller R, Hirsch A, Abdel-Halim* M, Hamed* M (2024)
Archiv der Pharmazie, 10.1002/ardp.202300656, 38304944

Inhibitors of the Elastase LasB for the Treatment of Pseudomonas aeruginosa Lung Infections

Publication
Konstantinovic J, Kany A, Alhayek A, Abdelsamie A, Sikandar A, Voos K, Yao Y, Andreas A, Shafiei R, Loretz B, Schönauer E, Bals R, Brandstetter H, Hartmann R, Ducho C, Lehr C, Beisswenger C, Müller R, Rox K, Haupenthal J, Hirsch A (2023)
ACS Cent. Sci., 9, 12, 2205-2215, 10.1021/acscentsci.3c01102, 38161367

Fighting antibiotic resistance-strategies and (pre)clinical developments to find new antibacterials

Publication
Walesch S, Birkelbach J, Jézéquel G, Haeckl F, Hegemann J, Hesterkamp T, Hirsch A, Hammann P, Müller R (2023)
EMBO reports, 24, 1, 10.15252/embr.202256033, 36533629

Expanding the Myxochelin Natural Product Family by Nicotinic Acid Containing Congeners

Publication
Frank N, Széles M, Akone S, Rasheed S, Hüttel S, Frewert S, Hamed M, Herrmann J, Schuler S, Hirsch A, Müller R (2021)
Molecules, 26, 16, 10.3390/molecules26164929

Protein‐Templated Hit Identification via an Ugi Four‐Component Reaction

Publication
Mancini F, Unver M, Elgaher W, Jumde V, Alhayek A, Lukat P, Herrmann J, Witte M, Köck M, Blankenfeldt W, Müller R, Hirsch A (2020)
Chem. Eur. J., 10.1002/chem.202002250

Synthesis and Biological Evaluation of Novel 2-Substituted ­Analogues of (–)-Pentenomycin I

Publication
Zisopoulou S, Bousis S, Haupenthal J, Herrmann J, Müller R, Hirsch A, Komiotis D, Gallos J, Stathakis C (2020)
Synlett, 31, 05, 475-481, 10.1055/s-0039-1690772

Advanced mutasynthesis studies on the natural α-pyrone antibiotic myxopyronin from Myxococcus fulvus

Publication
Sahner J, Sucipto H, Wenzel S, Groh M, Hartmann R, Müller R (2015)
ChemBioChem, 16, 946-953, 10.1002/cbic.201402666, 25757034

Towards the sustainable discovery and development of new antibiotics

Publication
Miethke M, Pieroni M, Weber T, Brönstrup M, Hammann P, Halby L, Arimondo P, Glaser P, Aigle B, Bode H, Moreira R, Li Y, Luzhetskyy A, Medema M, Pernodet J, Stadler M, Tormo J, Genilloud O, Truman A, Weissman K, Takano E, Sabatini S, Stegmann E, Brötz-Oesterhelt H, Wohlleben W, Seemann M, Empting M, Hirsch A, Loretz B, Lehr C, Titz A, Herrmann J, Jaeger T, Alt S, Hesterkamp T, Winterhalter M, Schiefer A, Pfarr K, Hoerauf A, Graz H, Graz M, Lindvall M, Ramurthy S, Karlén A, van Dongen M, Petkovic H, Keller A, Peyrane F, Donadio S, Fraisse L, Piddock L, Gilbert I, Moser H, Müller R (2021)
Nature reviews. Chemistry, 5, 10, 726-749, 10.1038/s41570-021-00313-1, 34426795