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Expanding the scaffold for bacterial RNA polymerase inhibitors: design, synthesis and structure–activity relationships of ureido-heterocyclic-carboxylic acids
Publication
Elgaher W,
Fruth M,
Groh M,
Haupenthal J,
Hartmann R
(2013)
RSC Adv, 4, 5, 2177-2194, 10.1039/C3RA45820B
RSC Adv, 4, 5, 2177-2194, 10.1039/C3RA45820B
New Theophylline Derivatives
Publication
Elgaher W
(2011)
Book
Book
Design and synthesis of some new theophylline derivatives with bronchodilator and antibacterial activities
Publication
Hayallah A,
Elgaher W,
Salem O,
Alim A
(2011)
Arch Pharm Res, 34, 1, 3-21, 10.1007/s12272-011-0101-8, 21468910
Arch Pharm Res, 34, 1, 3-21, 10.1007/s12272-011-0101-8, 21468910
Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections
Publication
Wagner S,
Sommer R,
Hinsberger S,
Lu C,
Hartmann R,
Empting M,
Titz A
(2016)
Journal of medicinal chemistry, 59, 13, 5929-69, 10.1021/acs.jmedchem.5b01698, 26804741
Journal of medicinal chemistry, 59, 13, 5929-69, 10.1021/acs.jmedchem.5b01698, 26804741
Targeting extracellular lectins of Pseudomonas aeruginosa with glycomimetic liposomes
Publication
Metelkina O,
Huck B,
O'Connor J,
Koch M,
Manz A,
Lehr C,
Titz A
(2022)
Journal of Materials Chemistry B, 10, 4, 537-548, 10.1039/d1tb02086b, 34985094
Journal of Materials Chemistry B, 10, 4, 537-548, 10.1039/d1tb02086b, 34985094
Nano-in-Microparticles for Aerosol Delivery of Antibiotic-Loaded, Fucose-Derivatized, and Macrophage-Targeted Liposomes to Combat Mycobacterial Infections: In Vitro Deposition, Pulmonary Barrier Interactions, and Targeted Delivery
Publication
Huck B,
Thiyagarajan D,
Bali A,
Boese A,
Besecke K,
Hozsa C,
Gieseler R,
Furch M,
Carvalho-Wodarz C,
Waldow F,
Schwudke D,
Metelkina O,
Titz A,
Huwer H,
Schwarzkopf K,
Hoppstädter J,
Kiemer A,
Koch M,
Loretz B,
Lehr C
(2022)
Advanced healthcare materials, 11, 11, 10.1002/adhm.202102117, 35112802
Advanced healthcare materials, 11, 11, 10.1002/adhm.202102117, 35112802
Point mutations in the ygiV promoter region lead to cystobactamid resistance and reduced virulence in E. coli
Publication
Müller R,
Risch T,
Kolling D,
Mostert D,
Seedorf T,
Heimann D,
Kohnhäuser D,
Deschner F,
Fries F,
Solga D,
Hilgers J,
Dastbaz J,
Hirsch A,
Brönstrup M,
Kirschning A,
Herrmann J,
Sieber S
(2024)
Book, 10.21203/rs.3.rs-3751821/v1
Book, 10.21203/rs.3.rs-3751821/v1
Development and evaluation of 2,4-disubstituted-5-aryl pyrimidine derivatives as antibacterial agents
Publication
Khalifa H,
Rasheed S,
Haupenthal J,
Herrmann J,
Mandour Y,
Abadi A,
Engel M,
Müller R,
Hirsch A,
Abdel-Halim* M,
Hamed* M
(2024)
Archiv der Pharmazie, 10.1002/ardp.202300656, 38304944
Archiv der Pharmazie, 10.1002/ardp.202300656, 38304944
Inhibitors of the Elastase LasB for the Treatment of Pseudomonas aeruginosa Lung Infections
Publication
Konstantinovic J,
Kany A,
Alhayek A,
Abdelsamie A,
Sikandar A,
Voos K,
Yao Y,
Andreas A,
Shafiei R,
Loretz B,
Schönauer E,
Bals R,
Brandstetter H,
Hartmann R,
Ducho C,
Lehr C,
Beisswenger C,
Müller R,
Rox K,
Haupenthal J,
Hirsch A
(2023)
ACS Cent. Sci., 9, 12, 2205-2215, 10.1021/acscentsci.3c01102, 38161367
ACS Cent. Sci., 9, 12, 2205-2215, 10.1021/acscentsci.3c01102, 38161367