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Double conjugate addition of dithiols to propargylic carbonyl systems to generate protected 1,3-dicarbonyl compounds
Publication
Sneddon H,
van den Heuvel A,
Hirsch A,
Booth R,
Shaw D,
Gaunt M,
Ley S
(2006)
The Journal of organic chemistry, 71, 7, 2715-25, 10.1021/jo052514s, 16555825
The Journal of organic chemistry, 71, 7, 2715-25, 10.1021/jo052514s, 16555825
pH-Responsive Dynaplexes as Potent Apoptosis Inductors by Intracellular Delivery of Survivin siRNA
Publication
Liu Y,
Ashmawy S,
Latta L,
Weiss A,
Kiefer A,
Nasr S,
Loretz B,
Hirsch A,
Lee S,
Lehr C
(2023)
Biomacromolecules, 24, 8, 3742-3754, 10.1021/acs.biomac.3c00424, 37523746
Biomacromolecules, 24, 8, 3742-3754, 10.1021/acs.biomac.3c00424, 37523746
N -Aryl-3-mercaptosuccinimides as Antivirulence Agents Targeting Pseudomonas aeruginosa Elastase and Clostridium Collagenases
Publication
Konstantinovic J,
Yahiaoui S,
Alhayek A,
Haupenthal J,
Schönauer E,
Andreas A,
Kany A,
Müller R,
Koehnke J,
Berger F,
Bischoff M,
Hartmann R,
Brandstetter H,
Hirsch A
(2020)
J. Med. Chem., 63, 15, 8359-8368, 10.1021/acs.jmedchem.0c00584
J. Med. Chem., 63, 15, 8359-8368, 10.1021/acs.jmedchem.0c00584
Discovery of the first small-molecule CsrA-RNA interaction inhibitors using biophysical screening technologies
Publication
Maurer C,
Fruth M,
Empting M,
Avrutina O,
Hossmann J,
Nadmid S,
Gorges J,
Herrmann J,
Kazmaier U,
Dersch P,
Muller R,
Hartmann R
(2016)
Future medicinal chemistry, 8, 9, 931-47, 10.4155/fmc-2016-0033, 27253623
Future medicinal chemistry, 8, 9, 931-47, 10.4155/fmc-2016-0033, 27253623
Surface plasmon resonance--more than a screening technology: insights in the binding mode of σ70:core RNAP inhibitors
Publication
Hüsecken K,
Hinsberger S,
Elgaher W,
Haupenthal J,
Hartmann R
(2014)
Future medicinal chemistry, 6, 14, 1551-65, 10.4155/fmc.14.105, 25367390
Future medicinal chemistry, 6, 14, 1551-65, 10.4155/fmc.14.105, 25367390
Expanding the scaffold for bacterial RNA polymerase inhibitors: design, synthesis and structure–activity relationships of ureido-heterocyclic-carboxylic acids
Publication
Elgaher W,
Fruth M,
Groh M,
Haupenthal J,
Hartmann R
(2013)
RSC Adv, 4, 5, 2177-2194, 10.1039/C3RA45820B
RSC Adv, 4, 5, 2177-2194, 10.1039/C3RA45820B
3D bioprinting ofE. coliMG1655 biofilms on human lung epithelial cells for building complexin vitroinfection models
Publication
Aliyazdi S,
Frisch S,
Hidalgo A,
Frank N,
Krug D,
Müller R,
Schaefer U,
Vogt T,
Loretz B,
Lehr C
(2023)
Biofabrication, 15, 3, 10.1088/1758-5090/acd95e, 37236174
Biofabrication, 15, 3, 10.1088/1758-5090/acd95e, 37236174
Korrektur der absoluten Konfiguration von Chelocardin und Amidochelocardin
Publication
Sikandar A,
Popoff A,
Jumde R,
Mándi A,
Kaur A,
Elgaher W,
Rosenberger L,
Hüttel S,
Jansen R,
Hunter M,
Köhnke J,
Hirsch A,
Kurtán T,
Müller R
(2023)
Angewandte Chemie (Weinheim an der Bergstrasse, Germany), 135, 40, 10.1002/ange.202306437
Angewandte Chemie (Weinheim an der Bergstrasse, Germany), 135, 40, 10.1002/ange.202306437
Adaptation of a Bacterial Multidrug Resistance System Revealed by the Structure and Function of AlbA
Publication
Sikandar A,
Cirnski K,
Testolin G,
Volz C,
Brönstrup M,
Kalinina O,
Müller R,
Koehnke J
(2018)
J. Am. Chem. Soc., 140, 48, 16641-16649, 10.1021/jacs.8b08895, 30422653
J. Am. Chem. Soc., 140, 48, 16641-16649, 10.1021/jacs.8b08895, 30422653
Bacterial RNAP Inhibitors: Synthesis and Evaluation of Prodrugs of Aryl‐ureidothiophene‐carboxylic acids
Publication
Ruthenbeck A,
Elgaher W,
Haupenthal J,
Hartmann R,
Meier C
(2017)
ChemistrySelect, 2, 35, 11899-11905, 10.1002/slct.201702574
ChemistrySelect, 2, 35, 11899-11905, 10.1002/slct.201702574