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Surface plasmon resonance--more than a screening technology: insights in the binding mode of σ70:core RNAP inhibitors
Publication
Hüsecken K,
Hinsberger S,
Elgaher W,
Haupenthal J,
Hartmann R
(2014)
Future medicinal chemistry, 6, 14, 1551-65, 10.4155/fmc.14.105, 25367390
Future medicinal chemistry, 6, 14, 1551-65, 10.4155/fmc.14.105, 25367390
Expanding the scaffold for bacterial RNA polymerase inhibitors: design, synthesis and structure–activity relationships of ureido-heterocyclic-carboxylic acids
Publication
Elgaher W,
Fruth M,
Groh M,
Haupenthal J,
Hartmann R
(2013)
RSC Adv, 4, 5, 2177-2194, 10.1039/C3RA45820B
RSC Adv, 4, 5, 2177-2194, 10.1039/C3RA45820B
Adaptation of a Bacterial Multidrug Resistance System Revealed by the Structure and Function of AlbA
Publication
Sikandar A,
Cirnski K,
Testolin G,
Volz C,
Brönstrup M,
Kalinina O,
Müller R,
Koehnke J
(2018)
J. Am. Chem. Soc., 140, 48, 16641-16649, 10.1021/jacs.8b08895, 30422653
J. Am. Chem. Soc., 140, 48, 16641-16649, 10.1021/jacs.8b08895, 30422653
Bacterial RNAP Inhibitors: Synthesis and Evaluation of Prodrugs of Aryl‐ureidothiophene‐carboxylic acids
Publication
Ruthenbeck A,
Elgaher W,
Haupenthal J,
Hartmann R,
Meier C
(2017)
ChemistrySelect, 2, 35, 11899-11905, 10.1002/slct.201702574
ChemistrySelect, 2, 35, 11899-11905, 10.1002/slct.201702574
Evolution of novel antibiotic Scaffolds targeting the nucleic acid machineries RNA polymerase, DNA gyrase, and topoisomerase IV
Publication
Elgaher W
(2016)
Thesis, 10.22028/D291-23193
Thesis, 10.22028/D291-23193
3D bioprinting ofE. coliMG1655 biofilms on human lung epithelial cells for building complexin vitroinfection models
Publication
Aliyazdi S,
Frisch S,
Hidalgo A,
Frank N,
Krug D,
Müller R,
Schaefer U,
Vogt T,
Loretz B,
Lehr C
(2023)
Biofabrication, 15, 3, 10.1088/1758-5090/acd95e, 37236174
Biofabrication, 15, 3, 10.1088/1758-5090/acd95e, 37236174
Korrektur der absoluten Konfiguration von Chelocardin und Amidochelocardin
Publication
Sikandar A,
Popoff A,
Jumde R,
Mándi A,
Kaur A,
Elgaher W,
Rosenberger L,
Hüttel S,
Jansen R,
Hunter M,
Köhnke J,
Hirsch A,
Kurtán T,
Müller R
(2023)
Angewandte Chemie (Weinheim an der Bergstrasse, Germany), 135, 40, 10.1002/ange.202306437
Angewandte Chemie (Weinheim an der Bergstrasse, Germany), 135, 40, 10.1002/ange.202306437
Crystobactamides
Publication
Sascha Baumann,
Jennifer Herrmann,
Kathrin Mohr,
Heinrich Steinmetz,
Klaus Gerth,
Ritesh Raju,
Rolf Müller,
Rolf W. Hartmann,
Mostafa Hamed,
Walid A. M. Elgaher,
Maria Moreno,
Franziska Gille,
Liang Liang Wang,
Andreas Kirschning,
Stephan Huettel
(2022)
Patent, C07C237/42; C07C237/44; C07K5/065; C07K7/06; C12N15/52; C12P13/02; A61K38/00, US11225503B2
Patent, C07C237/42; C07C237/44; C07K5/065; C07K7/06; C12N15/52; C12P13/02; A61K38/00, US11225503B2
Citraconic acid and derivatives thereof for use as a medicament
Publication
Frank Pessler,
Fangfang Chen,
Moritz Winterhoff,
Konrad Büssow,
Wulf Blankenfeldt,
Anna Hirsch,
Walid A. M. Elgaher
(2024)
Patent, A61K31/122; A61K31/194; A61P31/16; C07C57/42; C07C61/20; C07C69/593;, US20240368065A1
Patent, A61K31/122; A61K31/194; A61P31/16; C07C57/42; C07C61/20; C07C69/593;, US20240368065A1
Author Correction: Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways
Publication
Kurmasheva N,
Said A,
Wong B,
Kinderman P,
Han X,
Rahimic A,
Kress A,
Carter-Timofte M,
Holm E,
van der Horst D,
Kollmann C,
Liu Z,
Wang C,
Hoang H,
Kovalenko E,
Chrysopoulou M,
Twayana K,
Ottosen R,
Svenningsen E,
Begnini F,
Kiib A,
Kromm F,
Weiss H,
Di Carlo D,
Muscolini M,
Higgins M,
van der Heijden M,
Arulanandam R,
Bardoul A,
Tong T,
Ozsvar A,
Hou W,
Schack V,
Holm C,
Zheng Y,
Ruzek M,
Kalucka J,
La Vega L,
Elgaher W,
Korshoej A,
Lin R,
Hiscott J,
Poulsen T,
O'Neill L,
Roy D,
Rinschen M,
van Montfoort N,
Diallo J,
Farin H,
Alain T,
Olagnier D
(2024)
Nat Commun, 15, 1, 10.1038/s41467-024-55044-w, 39702301
Nat Commun, 15, 1, 10.1038/s41467-024-55044-w, 39702301