
Search
Nonphosphate inhibitors of IspE protein, a kinase in the non-mevalonate pathway for isoprenoid biosynthesis and a potential target for antimalarial therapy
Publication
Hirsch A,
Lauw S,
Gersbach P,
Schweizer W,
Rohdich F,
Eisenreich W,
Bacher A,
Diederich F
(2007)
ChemMedChem, 2, 6, 806-10, 10.1002/cmdc.200700014, 17361977
ChemMedChem, 2, 6, 806-10, 10.1002/cmdc.200700014, 17361977
Double conjugate addition of dithiols to propargylic carbonyl systems to generate protected 1,3-dicarbonyl compounds
Publication
Sneddon H,
van den Heuvel A,
Hirsch A,
Booth R,
Shaw D,
Gaunt M,
Ley S
(2006)
The Journal of organic chemistry, 71, 7, 2715-25, 10.1021/jo052514s, 16555825
The Journal of organic chemistry, 71, 7, 2715-25, 10.1021/jo052514s, 16555825
pH-Responsive Dynaplexes as Potent Apoptosis Inductors by Intracellular Delivery of Survivin siRNA
Publication
Liu Y,
Ashmawy S,
Latta L,
Weiss A,
Kiefer A,
Nasr S,
Loretz B,
Hirsch A,
Lee S,
Lehr C
(2023)
Biomacromolecules, 24, 8, 3742-3754, 10.1021/acs.biomac.3c00424, 37523746
Biomacromolecules, 24, 8, 3742-3754, 10.1021/acs.biomac.3c00424, 37523746
N -Aryl-3-mercaptosuccinimides as Antivirulence Agents Targeting Pseudomonas aeruginosa Elastase and Clostridium Collagenases
Publication
Konstantinovic J,
Yahiaoui S,
Alhayek A,
Haupenthal J,
Schönauer E,
Andreas A,
Kany A,
Müller R,
Koehnke J,
Berger F,
Bischoff M,
Hartmann R,
Brandstetter H,
Hirsch A
(2020)
J. Med. Chem., 63, 15, 8359-8368, 10.1021/acs.jmedchem.0c00584
J. Med. Chem., 63, 15, 8359-8368, 10.1021/acs.jmedchem.0c00584
Discovery of the first small-molecule CsrA-RNA interaction inhibitors using biophysical screening technologies
Publication
Maurer C,
Fruth M,
Empting M,
Avrutina O,
Hossmann J,
Nadmid S,
Gorges J,
Herrmann J,
Kazmaier U,
Dersch P,
Muller R,
Hartmann R
(2016)
Future medicinal chemistry, 8, 9, 931-47, 10.4155/fmc-2016-0033, 27253623
Future medicinal chemistry, 8, 9, 931-47, 10.4155/fmc-2016-0033, 27253623
Discovery of a novel, selective CK2 inhibitor class with an unusual basic scaffold
Publication
Khalifa H,
ElHady A,
Liu T,
Elgaher W,
Filhol-Cochet O,
Cochet C,
Abadi A,
Hamed M,
Abdel-Halim M,
Engel M
(2025)
European journal of medicinal chemistry, 282, 10.1016/j.ejmech.2024.117048, 39566243
European journal of medicinal chemistry, 282, 10.1016/j.ejmech.2024.117048, 39566243
Author Correction: Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways
Publication
Kurmasheva N,
Said A,
Wong B,
Kinderman P,
Han X,
Rahimic A,
Kress A,
Carter-Timofte M,
Holm E,
van der Horst D,
Kollmann C,
Liu Z,
Wang C,
Hoang H,
Kovalenko E,
Chrysopoulou M,
Twayana K,
Ottosen R,
Svenningsen E,
Begnini F,
Kiib A,
Kromm F,
Weiss H,
Di Carlo D,
Muscolini M,
Higgins M,
van der Heijden M,
Arulanandam R,
Bardoul A,
Tong T,
Ozsvar A,
Hou W,
Schack V,
Holm C,
Zheng Y,
Ruzek M,
Kalucka J,
La Vega L,
Elgaher W,
Korshoej A,
Lin R,
Hiscott J,
Poulsen T,
O'Neill L,
Roy D,
Rinschen M,
van Montfoort N,
Diallo J,
Farin H,
Alain T,
Olagnier D
(2024)
Nat Commun, 15, 1, 10.1038/s41467-024-55044-w, 39702301
Nat Commun, 15, 1, 10.1038/s41467-024-55044-w, 39702301
Novel and Extremely Sensitive NiAl2O4-NiO Nanostructures on an ITO Sensing Electrode for Enhanced Detection of Ascorbic Acid
Publication
Hammami A,
Bardaoui A,
Eissa S,
Elgaher W,
Chtourou R,
Messaoud O
(2024)
Molecules (Basel, Switzerland), 29, 12, 10.3390/molecules29122837, 38930902
Molecules (Basel, Switzerland), 29, 12, 10.3390/molecules29122837, 38930902
Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways
Publication
Kurmasheva N,
Said A,
Wong B,
Kinderman P,
Han X,
Rahimic A,
Kress A,
Carter-Timofte M,
Holm E,
van der Horst D,
Kollmann C,
Liu Z,
Wang C,
Hoang H,
Kovalenko E,
Chrysopoulou M,
Twayana K,
Ottosen R,
Svenningsen E,
Begnini F,
Kiib A,
Kromm F,
Weiss H,
Di Carlo D,
Muscolini M,
Higgins M,
van der Heijden M,
Arulanandam R,
Bardoul A,
Tong T,
Ozsvar A,
Hou W,
Schack V,
Holm C,
Zheng Y,
Ruzek M,
Kalucka J,
La Vega L,
Elgaher W,
Korshoej A,
Lin R,
Hiscott J,
Poulsen T,
O'Neill L,
Roy D,
Rinschen M,
van Montfoort N,
Diallo J,
Farin H,
Alain T,
Olagnier D
(2024)
Nat Commun, 15, 1, 10.1038/s41467-024-48422-x, 38750019
Nat Commun, 15, 1, 10.1038/s41467-024-48422-x, 38750019
Citraconic acid and derivatives thereof for use as a medicament
Publication
Frank Pessler,
Fangfang Chen,
Moritz Winterhoff,
Konrad Büssow,
Wulf Blankenfeldt,
Anna Hirsch,
Walid A. M. Elgaher
(2024)
Patent, A61K31/122; A61K31/194; A61P31/16; C07C57/42; C07C61/20; C07C69/593;, US20240368065A1
Patent, A61K31/122; A61K31/194; A61P31/16; C07C57/42; C07C61/20; C07C69/593;, US20240368065A1