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Researchers in HIPS Laboratory

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Searched for "drug". Displaying results 671 to 680 of 757.

Energy-Coupling Factor Transporters as Novel Antimicrobial Targets

Publication
Bousis S, Setyawati I, Diamanti E, Slotboom D, Hirsch A (2019)
Advanced Therapeutics, 2, 1800066, 10.1002/ADTP.201800066

The Alkylquinolone Repertoire of Pseudomonas aeruginosa is Linked to Structural Flexibility of the FabH-like 2-Heptyl-3-hydroxy-4(1H)-quinolone (PQS) Biosynthesis Enzyme PqsBC

Publication
Witzgall F, Depke T, Hoffmann M, Empting M, Brönstrup M, Müller R, Blankenfeldt W (2018)
Chembiochem : a European journal of chemical biology, 19, 14, 1531-1544, 10.1002/cbic.201800153, 29722462

Exploration of ligand binding modes towards the identification of compounds targeting HuR: a combined STD-NMR and Molecular Modelling approach

Publication
Vasile F, Della Volpe S, Ambrosio F, Costa G, Unver M, Zucal C, Rossi D, Martino E, Provenzani A, Hirsch A, Alcaro S, Potenza D, Collina S (2018)
Sci. Rep., 8, 1, 10.1038/s41598-018-32084-z

Lipid-DNAs as Solubilizers of m THPC

Publication
Liu Y, de Vries J, Liu Q, Hartman A, Wieland G, Wieczorek S, Börner H, Wiehe A, Buhler E, Stuart M, Browne W, Herrmann A, Hirsch A (2018)
Chem. Eur. J., 24, 4, 798-802, 10.1002/chem.201705206

Tackling Pseudomonas aeruginosa Virulence by a Hydroxamic Acid-Based LasB Inhibitor

Publication
Kany A, Sikandar A, Yahiaoui S, Haupenthal J, Walter I, Empting M, Köhnke J, Hartmann R (2018)
ACS chemical biology, 13, 9, 2449-2455, 10.1021/acschembio.8b00257, 30088919

Glucansucrase (mutant) enzymes from Lactobacillus reuteri 180 efficiently transglucosylate Stevia component rebaudioside A, resulting in a superior taste

Publication
Te Poele E, Devlamynck T, Jäger M, Gerwig G, van de Walle D, Dewettinck K, Hirsch A, Kamerling J, Soetaert W, Dijkhuizen L (2018)
Sci. Rep., 8, 1, 10.1038/s41598-018-19622-5, 29367749

Catechol-based substrates of chalcone synthase as a scaffold for novel inhibitors of PqsD

Publication
Allegretta G, Weidel E, Empting M, Hartmann R (2015)
European journal of medicinal chemistry, 90, 351-9, 10.1016/j.ejmech.2014.11.055, 25437621

Harnessing dynamic combinatorial chemistry in the search for new ligands for protein targets

Publication
Monjas L, Hirsch A (2015)
Future medicinal chemistry, 7, 16, 2095-8, 10.4155/fmc.15.146, 26510895

Structure-Based Optimization of Inhibitors of the Aspartic Protease Endothiapepsin

Publication
Hartman A, Mondal M, Radeva N, Klebe G, Hirsch A (2015)
International journal of molecular sciences, 16, 8, 19184-94, 10.3390/ijms160819184, 26287174

Dynamic combinatorial chemistry: a tool to facilitate the identification of inhibitors for protein targets

Publication
Mondal M, Hirsch A (2015)
Chemical Society reviews, 44, 8, 2455-88, 10.1039/c4cs00493k, 25706945