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Researchers in HIPS Laboratory

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Searched for "drug". Displaying results 641 to 650 of 748.

Nonphosphate inhibitors of IspE protein, a kinase in the non-mevalonate pathway for isoprenoid biosynthesis and a potential target for antimalarial therapy

Publication
Hirsch A, Lauw S, Gersbach P, Schweizer W, Rohdich F, Eisenreich W, Bacher A, Diederich F (2007)
ChemMedChem, 2, 6, 806-10, 10.1002/cmdc.200700014, 17361977

Double conjugate addition of dithiols to propargylic carbonyl systems to generate protected 1,3-dicarbonyl compounds

Publication
Sneddon H, van den Heuvel A, Hirsch A, Booth R, Shaw D, Gaunt M, Ley S (2006)
The Journal of organic chemistry, 71, 7, 2715-25, 10.1021/jo052514s, 16555825

Behavioral and electrophysiological responses of the male medfly, Ceratitis capitata, to thymol and carvacrol ethers

Publication
Tabanca N, Cloonan K, Nesterkina M, Gill M, Montgomery W, Kravchenko I, Kendra P (2024)
Pest management science, 10.1002/ps.8324, 39096116

Evaluation of ketoclomazone and its analogues as inhibitors of 1-deoxy-d-xylulose 5-phosphate synthases and other thiamine diphosphate (ThDP)-dependent enzymes

Publication
Chan A, Ho T, Fathoni I, Hamid R, Hirsch A, Saliba K, Leeper F (2024)
RSC Med. Chem., 15, 5, 1773-1781, 10.1039/D4MD00083H, 38784473

Studying Target-Engagement of Anti-Infectives by Solvent-Induced Protein Precipitation and Quantitative Mass Spectrometry

Publication
Bizzarri L, Steinbrunn D, Quennesson T, Lacour A, Bianchino G, Bravo P, Chaignon P, Lohse J, Mäser P, Seemann M, van Calenbergh S, Hirsch A, Hahne H (2024)
ACS Infect. Dis., 10, 12, 4087-4102, 10.1021/acsinfecdis.4c00417, 39566904

Synthesis and Structure of a Coordination Polymer of Ni(II) with 2-(4-Bromophenoxy)acetohydrazide

Publication
Martsynko ?, Nesterkina M, Finik ?, Tsymbaliuk K, Dyakonenko V, Shishkina S, Kravchenko I (2024)
Molbank, 2024, 2, 10.3390/M1819

Target repurposing unravels avermectins and derivatives as novel antibiotics inhibiting energy-coupling factor transporters (ECFTs)

Publication
Haupenthal J, Rafehi M, Kany A, Lespine A, Stefan K, Hirsch* A, Stefan* S (2024)
Arch. Pharm., 10.1002/ardp.202400267, 38896404

Not Every Hit-Identification Technique Works on 1-Deoxy-d-Xylulose 5-Phosphate Synthase (DXPS): Making the Most of a Virtual Screening Campaign

Publication
Johannsen S, Gierse R, Olshanova A, Smerznak E, Laggner C, Eschweiler L, Adeli Z, Hamid R, Alhayek A, Reiling N, Haupenthal J, Hirsch A (2023)
ChemMedChem, 10.1002/cmdc.202200590, 36896721

Exploring the Translational Gap of a Novel Class of Escherichia coli IspE Inhibitors

Publication
Ropponen H, Diamanti E, Johannsen S, Illarionov B, Hamid R, Jaki M, Sass P, Fischer M, Haupenthal J, Hirsch A (2023)
ChemMedChem, 10.1002/cmdc.202300346, 37718320

Genotoxic and mutational potential of monocyclic terpenoids (carvacrol, carvone and thymol) in Drosophila melanogaster

Publication
Nesterkina M, Bilokon S, Alieksieieva T, Kravchenko I, Hirsch A (2023)
Toxicol. Rep., 10, 10.1016/j.toxrep.2023.02.009