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Researchers in HIPS Laboratory

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Searched for "drug". Displaying results 631 to 640 of 708.

Structure-based design of potent small-molecule binders to the S-component of the ECF transporter for thiamine

Publication
Swier L, Monjas L, Guskov A, Voogd A, Erkens G, slotboom d, Hirsch A (2015)
ChemBioChem, 16, 5, 819-26, 10.1002/cbic.201402673, 25676607

Fighting malaria: structure-guided discovery of nonpeptidomimetic plasmepsin inhibitors

Publication
Huizing A, Mondal M, Hirsch A (2015)
Journal of medicinal chemistry, 58, 13, 5151-63, 10.1021/jm5014133, 25719272

Supramolecular chemistry … and beyond

Publication
Hirsch A (2015)
Angewandte Chemie (International ed. in English), 54, 38, 11013-4, 10.1002/anie.201506536, 26306880

Engineering a Constrained Peptidic Scaffold towards Potent and Selective Furin Inhibitors

Publication
Fittler H, Depp A, Avrutina O, Dahms S, Than M, Empting M, Kolmar H (2015)
Chembiochem : a European journal of chemical biology, 16, 17, 2441-4, 10.1002/cbic.201500447, 26426719

Catechol-based substrates of chalcone synthase as a scaffold for novel inhibitors of PqsD

Publication
Allegretta G, Weidel E, Empting M, Hartmann R (2015)
European journal of medicinal chemistry, 90, 351-9, 10.1016/j.ejmech.2014.11.055, 25437621

Harnessing dynamic combinatorial chemistry in the search for new ligands for protein targets

Publication
Monjas L, Hirsch A (2015)
Future medicinal chemistry, 7, 16, 2095-8, 10.4155/fmc.15.146, 26510895

Structure-Based Optimization of Inhibitors of the Aspartic Protease Endothiapepsin

Publication
Hartman A, Mondal M, Radeva N, Klebe G, Hirsch A (2015)
International journal of molecular sciences, 16, 8, 19184-94, 10.3390/ijms160819184, 26287174

Dynamic combinatorial chemistry: a tool to facilitate the identification of inhibitors for protein targets

Publication
Mondal M, Hirsch A (2015)
Chemical Society reviews, 44, 8, 2455-88, 10.1039/c4cs00493k, 25706945

De novo fragment-based design of inhibitors of DXS guided by spin-diffusion-based NMR spectroscopy

Publication
Masini T, Pilger J, Kroezen B, Illarionov B, Lottmann P, Fischer M, Griesinger C, Hirsch A (2014)
Chem. Sci., 5, 9, 3543-3551, 10.1039/C4SC00588K

A doubly hermaphroditic chiral crown ether

Publication
Hirsch A, Sirlin C, Harrowfield J, Lehn J (2014)
, 10.1039/C4CE00879K