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Identification of N,N-arylalkyl-picolinamide derivatives targeting the RNA-binding protein HuR, by combining biophysical fragment-screening and molecular hybridization
Publication
Della Volpe S,
Linciano P,
Listro R,
Tumminelli E,
Amadio M,
Bonomo I,
Elgaher W,
Adam S,
Hirsch A,
Boeckler F,
Vasile F,
Rossi D,
Collina S
(2021)
Bioorganic chemistry, 116, 10.1016/j.bioorg.2021.105305, 34482166
Bioorganic chemistry, 116, 10.1016/j.bioorg.2021.105305, 34482166
Redesigning of the cap conformation and symmetry of the diphenylethyne core to yield highly potent pan-genotypic NS5A inhibitors with high potency and high resistance barrier
Publication
Abdallah M,
Hamed M,
Frakolaki E,
Katsamakas S,
Vassilaki N,
Bartenschlager R,
Zoidis G,
Hirsch A,
Abdel-Halim M,
Abadi A
(2021)
European journal of medicinal chemistry, 10.1016/j.ejmech.2021.114034
European journal of medicinal chemistry, 10.1016/j.ejmech.2021.114034
Targeting the IspD Enzyme in the MEP Pathway: Identification of a Novel Fragment Class
Publication
Diamanti E,
Hamed M,
Lacour A,
Bravo P,
Illarionov B,
Fischer M,
Rottmann M,
Witschel M,
Hirsch A
(2021)
ChemMedChem, 10.1002/cmdc.202100679, 34918860
ChemMedChem, 10.1002/cmdc.202100679, 34918860
Phosphonate as a Stable Zinc‐Binding Group for “Pathoblocker” Inhibitors of Clostridial Collagenase H (ColH) (ChemMedChem 8/2021)
Publication
Voos K,
Schönauer E,
Alhayek A,
Haupenthal J,
Andreas A,
Müller R,
Hartmann R,
Brandstetter H,
Hirsch A,
Ducho C
(2021)
ChemMedChem, 16, 8, 1198-1198, 10.1002/cmdc.202100229
ChemMedChem, 16, 8, 1198-1198, 10.1002/cmdc.202100229
Novel (‒)-carvone derivatives as potential anticonvulsant and analgesic agents
Publication
Nesterkina M,
Barbalat D,
Konovalova I,
Shishkina S,
Atakay M,
Salih B,
Kravchenko I
(2021)
Natural product research, 35, 23, 4978-4987, 10.1080/14786419.2020.1756804, 32336164
Natural product research, 35, 23, 4978-4987, 10.1080/14786419.2020.1756804, 32336164
“Clicking“ fragment leads to novel dual-binding cholinesterase inhibitors
Publication
Moleda Z,
Zawadzka A,
Czarnocki Z,
Monjas L,
Hirsch A,
Budzianowski A,
Maurin J
(2021)
Bioorg Med Chem, 10.1016/j.bmc.2021.116269
Bioorg Med Chem, 10.1016/j.bmc.2021.116269
Design, synthesis, and biological evaluation of novel benzimidazole derivatives as sphingosine kinase 1 inhibitor
Publication
Khairat S,
Omar M,
Ragab F,
Roy S,
Turab Naqvi A,
Abdelsamie A,
Hirsch A,
Galal S,
Hassan M,
El Diwani H
(2021)
Archiv der Pharmazie, 354, 9, 10.1002/ardp.202100080, 34128259
Archiv der Pharmazie, 354, 9, 10.1002/ardp.202100080, 34128259
1st Spring Virtual Meeting on Medicinal Chemistry
Publication
Sousa M,
Marques M,
Faustino M
(2021)
Chemistry Proceedings, 4, 1, 10.3390/chemproc2021004001
Chemistry Proceedings, 4, 1, 10.3390/chemproc2021004001
Synthesis and pharmacological evaluation of novel naphthoquinone derivatives containing 1,2,4-triazine and 1,2,4-triazole moieties of methylene blue on the surface of a "core–shell" type catalyst for the Fenton system
Publication
Polish N,
Nesterkina M,
Protunkevych M,
Karkhut A,
Marintsova N,
Polovkovych S,
IKravchenko I,
Voskoboinik O,
Kovalenko S,
Karpenko O
(2021)
Vopr. Khim. Khim. Tekhnol., 5, 97-104, 10.32434/0321-4095-2021-138-5-97-104
Vopr. Khim. Khim. Tekhnol., 5, 97-104, 10.32434/0321-4095-2021-138-5-97-104
Simultaneous Complexation and Microextraction Using Verbenone Hydrazone as the Ligand with Slotted Quartz Tube-Flame Atomic Absorption Spectrometry (FAAS) for the Sensitive Determination of Copper
Publication
Özzeybek G,
Borahan T,
Nesterkina M,
Kravchenko I,
Bakirdere S
(2021)
Analytical letters, 54, 14, 2376-2386, 10.1080/00032719.2020.1866594
Analytical letters, 54, 14, 2376-2386, 10.1080/00032719.2020.1866594