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Researchers in HIPS Laboratory

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Searched for "drug". Displaying results 571 to 580 of 748.

Single-domain antibodies for biomedical applications

Publication
Krah S, Schröter C, Zielonka S, Empting M, Valldorf B, Kolmar H (2016)
Immunopharmacol. Immunotoxicol., 38, 1, 21-8, 10.3109/08923973.2015.1102934, 26551147

Synthesis and Anticonvulsant Activity of New Calix[4]Arene Derivatives Containing Gamma-Aminobutyric Acid Moieties

Publication
Nesterkina M, Alekseeva E, Kravchenko I (2016)
Pharm Chem J, 49, 12, 825-829, 10.1007/s11094-016-1380-7

Proteoid Dynamers with Tunable Properties

Publication
Liu Y, Stuart M, Buhler E, Lehn J, Hirsch A (2016)
, 10.1002/ADFM.201601612

Towards the evaluation in an animal disease model: Fluorinated 17β-HSD1 inhibitors showing strong activity towards both the human and the rat enzyme

Publication
Abdelsamie A, Bey E, Gargano E, van Koppen C, Empting M, Frotscher M (2015)
European journal of medicinal chemistry, 103, 56-68, 10.1016/j.ejmech.2015.08.030, 26322835

Novel PqsR Inverse Agonists

Publication
Hamed M (2015)
Patent, EP 201523196

Fragment growing exploiting dynamic combinatorial chemistry of inhibitors of the aspartic protease endothiapepsin

Publication
Mondal M, Groothuis D, Hirsch A (2015)
, 10.1039/C5MD00157A

Validation of a homology model of Mycobacterium tuberculosis DXS: rationalization of observed activities of thiamine derivatives as potent inhibitors of two orthologues of DXS

Publication
Masini T, Lacy B, Monjas L, Hawksley D, Voogd A, Illarionov B, Iqbal A, Leeper F, Fischer M, Kontoyianni M, Hirsch A (2015)
Organic & biomolecular chemistry, 13, 46, 11263-77, 10.1039/c5ob01666e, 26411373

Structure-based design of potent small-molecule binders to the S-component of the ECF transporter for thiamine

Publication
Swier L, Monjas L, Guskov A, Voogd A, Erkens G, slotboom d, Hirsch A (2015)
ChemBioChem, 16, 5, 819-26, 10.1002/cbic.201402673, 25676607

Fighting malaria: structure-guided discovery of nonpeptidomimetic plasmepsin inhibitors

Publication
Huizing A, Mondal M, Hirsch A (2015)
Journal of medicinal chemistry, 58, 13, 5151-63, 10.1021/jm5014133, 25719272

Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism

Publication
Chen F, Elgaher W, Winterhoff M, Büssow K, Waqas F, Graner E, Pires-Afonso Y, Casares Perez L, La Vega L, Sahini N, Czichon L, Zobl W, Zillinger T, Shehata M, Pleschka S, Bähre H, Falk C, Michelucci A, Schuchardt S, Blankenfeldt W, Hirsch A, Pessler F (2022)
Nature metabolism, 4, 5, 534-546, 10.1038/s42255-022-00577-x, 35655026