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Researchers in HIPS Laboratory

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Searched for "drug". Displaying results 571 to 580 of 756.

PHARMACOLOGICAL AND PHYSICO-CHEMICAL PROPERTIES OF COMPOSITIONS BASED ON BIOSURFACTANTS AND N-CONTAINING HETEROCYCLIC DERIVATIVES OF 1,4-NAPHTHOQUINONE

Publication
Polish N, Nesterkina M, Karkhut A, Marintsova N, Zhurakhivska L, Volianiuk K, Pokynbroda T, Kravchenko I, Karpenko E (2022)
J microb biotech food sci, 12, 3, 10.55251/jmbfs.5956

Structural analysis of 1-deoxy-D-xylulose 5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding

Publication
Hamid R, Adam S, Lacour A, Gomez L, Hirsch A (2022)
bioRxiv, 10.1101/2022.07.04.498669

Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism

Publication
Chen F, Elgaher W, Winterhoff M, Büssow K, Waqas F, Graner E, Pires-Afonso Y, Casares Perez L, La Vega L, Sahini N, Czichon L, Zobl W, Zillinger T, Shehata M, Pleschka S, Bähre H, Falk C, Michelucci A, Schuchardt S, Blankenfeldt W, Hirsch A, Pessler F (2022)
Nature metabolism, 4, 5, 534-546, 10.1038/s42255-022-00577-x, 35655026

Targeting Extracellular Bacterial Proteases for the Development of Novel Antivirulence Agents

Publication
Kaya C, Hirsch A (2022)
Chimia, 76, 5, 10.2533/chimia.2022.402

Screening of Natural Products and Small Molecules Uncovers Novel Coronavirus 1a/1b Frameshifting Inhibitors with Antiviral Properties

Publication
Kibe A, Elgaher W, Rand U, Zimmer M, Kany A, Hermann J, Müller R, Cicin-Sain L, Hirsch A, Caliskan N (2022)
SSRN Journal, 10.2139/ssrn.4157446

Respiratory Syncytial Virus Two-Step Infection Screen Reveals Inhibitors of Early and Late Life Cycle Stages

Publication
Sake S, Kosch C, Blockus S, Haid S, Gunesch A, Zhang X, Friesland M, Trummer S, Grethe C, Kühnel A, Rückert J, Duprex W, Huang J, Rameix-Welti M, Empting M, Fischer N, Hirsch A, Schulz T, Pietschmann T (2022)
Antimicrobial agents and chemotherapy, 10.1128/aac.01032-22, 36346232

Identification of RAD51-BRCA2 Inhibitors Using N-Acylhydrazone-Based Dynamic Combinatorial Chemistry

Publication
Bagnolini G, Balboni B, Schipani F, Gioia D, Veronesi M, Franco F, Kaya C, Jumde R, Ortega J, Girotto S, Hirsch A, Roberti M, Cavalli A (2022)
ACS Med. Chem. Lett., 13, 8, 1262-1269, 10.1021/acsmedchemlett.2c00063, 35978685

Rheological Properties of Hyaluronic Acid Diluted Solutions as Components of Cosmetics

Publication
Svetlana Saitarly, Yuriy Pushkarev, Nesterkina M, Serhat Öztürk, Iryna Kravchenko (2021)
Biointerface Res Appl Chem, 12, 2, 1907-1915, 10.33263/BRIAC122.19071915

Identification of a 1-deoxy-D-xylulose-5-phosphate synthase (DXS) mutant with improved crystallographic properties

Publication
Gierse R, Reddem E, Alhayek A, Baitinger D, Hamid Z, Jakobi H, Laber B, Lange G, Hirsch A, Groves (2021)
Biochemical and Biophysical Research Communications, 539, 10.1016/j.bbrc.2020.12.069, 33421767

Substrate-Inspired Fragment Merging and Growing Affords Efficacious LasB Inhibitors

Publication
Kaya C, Walter I, Yahiaoui S, Sikandar A, Alhayek A, Konstantinovic J, Kany A, Haupenthal J, Köhnke J, Hartmann R, Hirsch A (2021)
Angewandte Chemie (International ed. in English), 10.1002/anie.202112295, 34762767