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A New Class of Polyion Complex Vesicles (PIC-somes) to Improve Antimicrobial Activity of Tobramycin in Pseudomonas Aeruginosa Biofilms
Publication
Yildirim T,
Bali A,
Koch M,
Paul P,
Latta L,
Schneider-Daum N,
Gallei M,
Lehr C
(2024)
Small (Weinheim an der Bergstrasse, Germany), 20, 40, 10.1002/smll.202401926, 38829185
Small (Weinheim an der Bergstrasse, Germany), 20, 40, 10.1002/smll.202401926, 38829185
Preparation and characterization of cationic PLGA nanospheres as DNA carriers
Publication
Ravi Kumar M,
Bakowsky U,
Lehr C
(2004)
Biomaterials, 25, 10, 1771-1777, 10.1016/j.biomaterials.2003.08.069
Biomaterials, 25, 10, 1771-1777, 10.1016/j.biomaterials.2003.08.069
Size-dependent bioadhesion of micro- and nanoparticulate carriers to the inflamed colonic mucosa
Publication
Lamprecht A,
Schäfer U,
Lehr C
(2001)
Pharmaceutical research, 18, 6, 788-793, 10.1023/A:1011032328064
Pharmaceutical research, 18, 6, 788-793, 10.1023/A:1011032328064
Aspherical and Spherical InvA497-Functionalized Nanocarriers for Intracellular Delivery of Anti-Infective Agents
Publication
Castoldi A,
Empting M,
Rossi C,
Mayr K,
Dersch P,
Hartmann R,
Müller R,
Gordon S,
Lehr C
(2018)
Pharm Res, 36, 1, 10.1007/s11095-018-2521-3, 30519925
Pharm Res, 36, 1, 10.1007/s11095-018-2521-3, 30519925
Arg-biodynamers as antibiotic potentiators through interacting with Gram-negative outer membrane lipopolysaccharides
Publication
Kamal M,
Bassil J,
Loretz B,
Hirsch A,
Lee S,
Lehr C
(2024)
Eur J Pharm Biopharm, 200, 10.1016/j.ejpb.2024.114336, 38795784
Eur J Pharm Biopharm, 200, 10.1016/j.ejpb.2024.114336, 38795784
Disrupting Kaposi's Sarcoma-Associated Herpesvirus (KSHV) Latent Replication with a Small Molecule Inhibitor
Publication
Berwanger A,
Stein S,
Kany A,
Gartner M,
Loretz B,
Lehr C,
Hirsch A,
Schulz T,
Empting M
(2023)
Journal of medicinal chemistry, 66, 15, 10782-10790, 10.1021/acs.jmedchem.3c00990, 37506283
Journal of medicinal chemistry, 66, 15, 10782-10790, 10.1021/acs.jmedchem.3c00990, 37506283
Proteoid biodynamers for safe mRNA transfection via pH-responsive nanorods enabling endosomal escape
Publication
Lee S,
Nasr S,
Rasheed S,
Liu Y,
Hartwig O,
Kaya C,
Boese A,
Koch M,
Herrmann J,
Müller R,
Loretz B,
Buhler E,
Hirsch A,
Lehr C
(2022)
Journal of controlled release : official journal of the Controlled Release Society, 353, 915-929, 10.1016/j.jconrel.2022.12.018, 36521693
Journal of controlled release : official journal of the Controlled Release Society, 353, 915-929, 10.1016/j.jconrel.2022.12.018, 36521693
Squalenyl Hydrogen Sulfate Nanoparticles for Simultaneous Delivery of Tobramycin and an Alkylquinolone Quorum Sensing Inhibitor Enable the Eradication of P. aeruginosa Biofilm Infections
Publication
Ho D,
Murgia X,
Rossi C,
Christmann R,
Hüfner de Mello Martins A,
Koch M,
Andreas A,
Herrmann J,
Müller R,
Empting M,
Hartmann R,
Desmaele D,
Loretz B,
Couvreur P,
Lehr C
(2020)
Angewandte Chemie (International ed. in English), 10.1002/anie.202001407, 32243047
Angewandte Chemie (International ed. in English), 10.1002/anie.202001407, 32243047
An Outer Membrane Vesicle-Based Permeation Assay (OMPA) for Assessing Bacterial Bioavailability
Publication
Richter R,
Kamal M,
Koch M,
Niebuur B,
Huber A,
Goes A,
Volz C,
Vergalli J,
Kraus T,
Müller R,
Schneider-Daum N,
Fuhrmann G,
Pagès J,
Lehr C
(2022)
Advanced healthcare materials, 11, 5, 10.1002/adhm.202101180, 34614289
Advanced healthcare materials, 11, 5, 10.1002/adhm.202101180, 34614289
Novel Compounds Targeting the RNA-Binding Protein HuR. Structure-Based Design, Synthesis, and Interaction Studies
Publication
Della Volpe S,
Nasti R,
Queirolo M,
Unver M,
Jumde V,
Dömling A,
Vasile F,
Potenza D,
Ambrosio F,
Costa G,
Alcaro S,
Zucal C,
Provenzani A,
Di Giacomo M,
Rossi D,
Hirsch A,
Collina S
(2019)
ACS Med. Chem. Lett., 10, 4, 615-620, 10.1021/acsmedchemlett.8b00600, 30996806
ACS Med. Chem. Lett., 10, 4, 615-620, 10.1021/acsmedchemlett.8b00600, 30996806