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Mechanistic profiling of the release kinetics of siRNA from lipidoid-polymer hybrid nanoparticles in vitro and in vivo after pulmonary administration
Publication
Thanki K,
van Eetvelde D,
Geyer A,
Fraire J,
Hendrix R,
van Eygen H,
Putteman E,
Sami H,
Souza Carvalho-Wodarz C,
Franzyk H,
Nielsen H,
Braeckmans K,
Lehr C,
Ogris M,
Foged C
(2019)
Journal of controlled release : official journal of the Controlled Release Society, 310, 82-93, 10.1016/j.jconrel.2019.08.004, 31398360
Journal of controlled release : official journal of the Controlled Release Society, 310, 82-93, 10.1016/j.jconrel.2019.08.004, 31398360
Exploring the conformational landscapes of HIV protease structural ensembles using principal component analysis
Publication
Hassan S,
Srikakulam S,
Chandramohan Y,
Thangam M,
Muthukumar S,
Gayathri Devi P,
Hanna L
(2018)
Proteins, 86, 9, 990-1000, 10.1002/prot.25534, 30051500
Proteins, 86, 9, 990-1000, 10.1002/prot.25534, 30051500
Vibrational spectroscopic imaging and live cell video microscopy for studying differentiation of primary human alveolar epithelial cells
Publication
Vukosavljevic B,
Hittinger M,
Hachmeister H,
Pilger C,
Murgia X,
Gepp M,
Gentile L,
Huwer H,
Schneider-Daum N,
Huser T,
Lehr C,
Windbergs M
(2018)
Journal of biophotonics, 10.1002/jbio.201800052, 30597770
Journal of biophotonics, 10.1002/jbio.201800052, 30597770
Human airway mucus alters susceptibility of Pseudomonas aeruginosa biofilms to tobramycin, but not colistin
Publication
Müller L,
Murgia X,
Siebenbürger L,
Börger C,
Schwarzkopf K,
Sewald K,
Häussler S,
Braun A,
Lehr C,
Hittinger M,
Wronski S
(2018)
The Journal of antimicrobial chemotherapy, 73, 10, 2762-2769, 10.1093/jac/dky241, 29982453
The Journal of antimicrobial chemotherapy, 73, 10, 2762-2769, 10.1093/jac/dky241, 29982453
A novel co-culture model of human bronchial epithelial cells and Pseudomonas aeruginosa biofilms to mimic chronic lung infections in cystic fibrosis
Publication
Juntke J
(2018)
UnpublishedWork, 10.22028/D291-27897
UnpublishedWork, 10.22028/D291-27897
Chemically modified h CFTR mRNAs recuperate lung function in a mouse model of cystic fibrosis
Publication
Haque,
A. K. M. Ashiqul,
Dewerth A,
Antony J,
Riethmüller J,
Schweizer G,
Weinmann P,
Latifi N,
Yasar H,
Pedemonte N,
Sondo E,
Weidensee B,
Ralhan A,
Laval J,
Schlegel P,
Seitz C,
Loretz B,
Lehr C,
Handgretinger R,
Kormann M
(2018)
Scientific Reports, 8, 1, 10.1038/s41598-018-34960-0
Scientific Reports, 8, 1, 10.1038/s41598-018-34960-0
In Vitro Model of the Gram-Negative Bacterial Cell Envelope for Investigation of Anti-Infective Permeation Kinetics
Publication
Graef F,
Richter R,
Fetz V,
Murgia X,
Rossi C,
Schneider-Daum N,
Allegretta G,
Elgaher W,
Haupenthal J,
Empting M,
Beckmann F,
Brönstrup M,
Hartmann R,
Gordon S,
Lehr C
(2018)
ACS infectious diseases, 4, 8, 1188-1196, 10.1021/acsinfecdis.7b00165, 29750862
ACS infectious diseases, 4, 8, 1188-1196, 10.1021/acsinfecdis.7b00165, 29750862
Polysaccharide Submicrocarrier for Improved Pulmonary Delivery of Poorly Soluble Anti-infective Ciprofloxacin
Publication
Ho D,
Costa A,
Rossi C,
Souza Carvalho-Wodarz C,
Loretz B,
Lehr C
(2018)
Molecular pharmaceutics, 15, 3, 1081-1096, 10.1021/acs.molpharmaceut.7b00967, 29425049
Molecular pharmaceutics, 15, 3, 1081-1096, 10.1021/acs.molpharmaceut.7b00967, 29425049
Combining MucilAir™ and Vitrocell® Powder Chamber for the In Vitro Evaluation of Nasal Ointments in the Context of Aerosolized Pollen
Publication
Metz J,
Knoth K,
Groß H,
Lehr C,
Stäbler C,
Bock U,
Hittinger M
(2018)
Pharmaceutics, 10, 2, 10.3390/pharmaceutics10020056, 29747472
Pharmaceutics, 10, 2, 10.3390/pharmaceutics10020056, 29747472
A miRNA181a/NFAT5 axis links impaired T cell tolerance induction with autoimmune type 1 diabetes
Publication
Serr I,
Scherm M,
Zahm A,
Schug J,
Flynn V,
Hippich M,
Kälin S,
Becker M,
Achenbach P,
Nikolaev A,
Gerlach K,
Liebsch N,
Loretz B,
Lehr C,
Kirchner B,
Spornraft M,
Haase B,
Segars J,
Küper C,
Palmisano R,
Waisman A,
Willis R,
Kim W,
Weigmann B,
Kaestner K,
Ziegler A,
Daniel C
(2018)
Science translational medicine, 10, 422, 10.1126/scitranslmed.aag1782, 29298866
Science translational medicine, 10, 422, 10.1126/scitranslmed.aag1782, 29298866