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Transport of 20 marketed anti-infectives across the human lung epithelium in vitro
Publication
Simon S,
Westwood M,
Shanmugalingam T,
Cantrill C,
Lehr C
(2026)
Int. J. Pharm., 695, 10.1016/j.ijpharm.2026.126721, 41771312
Int. J. Pharm., 695, 10.1016/j.ijpharm.2026.126721, 41771312
Staphylococcal proliferation on skin models to investigate novel anti-infective treatments against dysbiosis
Publication
Frisch S,
Aliyazdi S,
Rehner J,
Schmartz G,
Gevaerd C,
Latta L,
Veldung B,
Becker S,
Keller A,
Schaefer U,
Loretz B,
Vogt T,
Lehr C
(2026)
Bioengineering & Transla Med, 11, 3, 10.1002/btm2.70124, 42272967
Bioengineering & Transla Med, 11, 3, 10.1002/btm2.70124, 42272967
Highly potent quinoxalinediones inhibit α-hemolysin and ameliorate Staphylococcus aureus lung infections
Publication
Shekhar A,
Di Lucrezia R,
Jerye K,
Korotkov V,
Harmrolfs K,
Rox K,
Weich H,
Ghai I,
Delhommel F,
Becher I,
Degenhart C,
Fansa E,
Unger A,
Habenberger P,
Klebl B,
Lukat P,
Schmelz S,
Henke S,
Borgert S,
Lang J,
Sasse F,
Diestel R,
Richter C,
Schneider-Daum N,
Hinkelmann B,
Niemz J,
Lehr C,
Jänsch L,
Huehn J,
Alm R,
Savitski M,
Welte T,
Hesterkamp T,
Sattler M,
Winterhalter M,
Blankenfeldt W,
Medina E,
Bilitewski U,
Dinkel K,
Brönstrup M
(2025)
Cell Host Microbe, 33, 4, 560-572, 10.1016/j.chom.2025.03.006, 40168998
Cell Host Microbe, 33, 4, 560-572, 10.1016/j.chom.2025.03.006, 40168998
Soft mist inhaler nebulization by Rayleigh-breakup largely preserves functional integrity of liposomal mRNA in respirable aerosols
Publication
Biesel A,
Maamari S,
Salaw N,
Sibum I,
Buchmann N,
Loretz B,
Zeisberg E,
Lehr C
(2025)
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 214, 10.1016/j.ejps.2025.107300, 41027537
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 214, 10.1016/j.ejps.2025.107300, 41027537
Proteomic profiling of macrophages: effects of inflammatory activation and anti-inflammatory treatment with IBD therapeutics
Publication
Lichtner S,
Schunck K,
Frey J,
Osti J,
Dannheimer S,
Schnur S,
Lehr C,
Schneider M,
Hittinger M
(2025)
Eur J Pharm Biopharm, 216, 10.1016/j.ejpb.2025.114869, 40975501
Eur J Pharm Biopharm, 216, 10.1016/j.ejpb.2025.114869, 40975501
A novel lipopolyplex platform for dual mRNA delivery via core- and surface-loading
Publication
Gabelmann A,
Mansouri-Ghahnavieh E,
Koch M,
Shinde P,
Guzmán C,
Loretz B,
Lehr C
(2025)
Journal of controlled release : official journal of the Controlled Release Society, 384, 10.1016/j.jconrel.2025.113875, 40412659
Journal of controlled release : official journal of the Controlled Release Society, 384, 10.1016/j.jconrel.2025.113875, 40412659
Polymer Blend Controls Nanoparticles' Surface Charge for Improved Mucus Penetration and Epithelial Cell Adhesion
Publication
Stevens C,
Sevarika B,
Wilson B,
Wang C,
Cárcamo-Oyarce G,
Romeo J,
Degen G,
Kassis T,
Lehr C,
Carrier R,
Ribbeck K,
Prud'homme R
(2025)
Nano Lett., 25, 49, 16963-16969, 10.1021/acs.nanolett.5c02487, 41269876
Nano Lett., 25, 49, 16963-16969, 10.1021/acs.nanolett.5c02487, 41269876
Exploring the future of mRNA delivery: Beyond lipid nanoparticles
Publication
Gabelmann A,
Biesel A,
Loretz B,
Lehr C
(2025)
Biochemical and Biophysical Research Communications, 778, 10.1016/j.bbrc.2025.152347, 40683021
Biochemical and Biophysical Research Communications, 778, 10.1016/j.bbrc.2025.152347, 40683021
Nanoparticles across mucosal barriers: Differentiating mucoadhesion from mucopenetration using single particle tracking
Publication
Tollemeto M,
Thamdrup L,
Hatzakis N,
Lehr C,
van Hest J,
Boisen A
(2025)
Journal of controlled release : official journal of the Controlled Release Society, 388, Pt 1, 10.1016/j.jconrel.2025.114268, 41027531
Journal of controlled release : official journal of the Controlled Release Society, 388, Pt 1, 10.1016/j.jconrel.2025.114268, 41027531
Mapping the ABC transporter landscape in the human lung: A comprehensive characterisation of P-gp, MRP1 and BCRP expression and functional activity in human lung epithelial cells
Publication
Simon S,
Shanmugalingam T,
Neu T,
Schneider-Daum N,
Cantrill C,
Lehr C
(2025)
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 215, 10.1016/j.ejps.2025.107333, 41110516
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 215, 10.1016/j.ejps.2025.107333, 41110516