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Researchers in HIPS Laboratory

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Searched for "drug". Displaying results 241 to 250 of 761.

Human alveolar epithelial cells expressing tight junctions to model the air-blood barrier

Publication
Kuehn A, Kletting S, Souza Carvalho-Wodarz C, Repnik U, Griffiths G, Fischer U, Meese E, Huwer H, Wirth D, May T, Schneider-Daum N, Lehr C (2016)
ALTEX, 33, 3, 251-60, 10.14573/altex.1511131, 26985677

The bacterial cell envelope as delimiter of anti-infective bioavailability – An in vitro permeation model of the Gram-negative bacterial inner membrane

Publication
Graef F, Vukosavljevic B, Michel J, Wirth M, Ries O, De Rossi C, Windbergs M, Rosilio V, Ducho C, Gordon S, Lehr C (2016)
Journal of Controlled Release, 243, 214-224, 10.1016/j.jconrel.2016.10.018

Optical tweezers reveal relationship between microstructure and nanoparticle penetration of pulmonary mucus

Publication
Kirch J, Schneider A, Abou B, Hopf A, Schaefer U, Schneider M, Schall C, Wagner C, Lehr C (2012)
Proceedings of the National Academy of Sciences of the United States of America, 109, 45, 18355-18360, 10.1073/pnas.1214066109

A three-dimensional coculture of enterocytes, monocytes and dendritic cells to model inflamed intestinal mucosa in vitro

Publication
Leonard F, Collnot E, Lehr C (2010)
Molecular pharmaceutics, 7, 6, 2103-2119, 10.1021/mp1000795

Transferring Microclusters of P. aeruginosa Biofilms to the Air-Liquid Interface of Bronchial Epithelial Cells for Repeated Deposition of Aerosolized Tobramycin

Publication
Horstmann J, Laric A, Boese A, Yildiz D, Röhrig T, Empting M, Frank N, Krug D, Müller R, Schneider-Daum N, Souza Carvalho-Wodarz C, Lehr C (2022)
ACS infectious diseases, 8, 1, 137-149, 10.1021/acsinfecdis.1c00444, 34919390

A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms

Publication
Schütz C, Ho D, Hamed M, Abdelsamie A, Röhrig T, Herr C, Kany A, Rox K, Schmelz S, Siebenbürger L, Wirth M, Börger C, Yahiaoui S, Bals R, Scrima A, Blankenfeldt W, Horstmann J, Christmann R, Murgia X, Koch M, Berwanger A, Loretz B, Hirsch A, Hartmann R, Lehr C, Empting M (2021)
Advanced science (Weinheim, Baden-Wurttemberg, Germany), 8, 12, 10.1002/advs.202004369, 34165899

A hydrogel-based in vitro assay for the fast prediction of antibiotic accumulation in Gram-negative bacteria

Publication
Richter R, Kamal M, García-Rivera M, Kaspar J, Junk M, Elgaher W, Srikakulam S, Gress A, Beckmann A, Grißmer A, Meier C, Vielhaber M, Kalinina O, Hirsch A, Hartmann R, Brönstrup M, Schneider-Daum N, Lehr C (2020)
Materials today. Bio, 8, 10.1016/j.mtbio.2020.100084, 33313504

pH-Dependent morphology and optical properties of lysine-derived molecular biodynamers

Publication
Lee S, Kaya C, Jang H, Koch M, Loretz B, Buhler E, Lehr C, Hirsch A (2020)
Mater. Chem. Front., 4, 3, 905-909, 10.1039/C9QM00651F

Micro-rheological properties of lung homogenates correlate with infection severity in a mouse model of Pseudomonas aeruginosa lung infection

Publication
Murgia X, Kany A, Herr C, Ho D, Rossi C, Bals R, Lehr C, Hirsch A, Hartmann R, Empting M, Röhrig T (2020)
Scientific Reports, 10, 1, 10.1038/s41598-020-73459-5, 33020513

Design and evaluation of nanostructured lipid carrier of Bergenin isolated from Pentaclethra macrophylla for anti-inflammatory effect on lipopolysaccharide-induced inflammatory responses in macrophages

Publication
Nnamani P, Nwagwu C, Diovu E, Abonyi O, Nesterkina M, Neu T, Richter C, Loretz B, Lehr C (2024)
Eur J Pharm Biopharm, 200, 10.1016/j.ejpb.2024.114307, 38685438