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Spray-dried lactose-leucine microparticles for pulmonary delivery of antimycobacterial nanopharmaceuticals
Publication
Thiyagarajan D,
Huck B,
Nothdurft B,
Koch M,
Rudolph D,
Rutschmann M,
Feldmann C,
Hozsa C,
Furch M,
Besecke K,
Gieseler R,
Loretz B,
Lehr C
(2021)
Drug delivery and translational research, 11, 4, 1766-1778, 10.1007/s13346-021-01011-7, 34101127
Drug delivery and translational research, 11, 4, 1766-1778, 10.1007/s13346-021-01011-7, 34101127
Advancing human in vitro pulmonary disease models in preclinical research: opportunities for lung-on-chips
Publication
Artzy-Schnirman A,
Lehr C,
Sznitman J
(2020)
Expert Opinion on Drug Delivery, 17, 5, 621-625, 10.1080/17425247.2020.1738380, 32129105
Expert Opinion on Drug Delivery, 17, 5, 621-625, 10.1080/17425247.2020.1738380, 32129105
Baicalin lipid nanocapsules for treatment of glioma: characterization, mechanistic cytotoxicity, and pharmacokinetic evaluation
Publication
Ibrahim A,
Abdel Gaber S,
Fawzi Kabil M,
Ahmed-Farid O,
Hirsch A,
El-Sherbiny I,
Nasr M
(2022)
Expert Opin. Drug Deliv., 19, 11, 1549-1560, 10.1080/17425247.2022.2139370, 36287914
Expert Opin. Drug Deliv., 19, 11, 1549-1560, 10.1080/17425247.2022.2139370, 36287914
Realizing time-staggered expression of nucleic acid-encoded proteins by co-delivery of messenger RNA and plasmid DNA on a single nanocarrier
Publication
Nasr S,
Paul P,
Loretz B,
Lehr C
(2024)
Drug delivery and translational research, 14, 12, 3339-3353, 10.1007/s13346-024-01668-w, 39009932
Drug delivery and translational research, 14, 12, 3339-3353, 10.1007/s13346-024-01668-w, 39009932
Overview of Inhaled Nanopharmaceuticals
Publication
Barthold S,
Kunschke N,
Murgia X,
Loretz B,
Carvalho-Wodarz C,
Lehr C
(2023)
Journal of aerosol medicine and pulmonary drug delivery, 36, 3, 144-151, 10.1089/jamp.2023.29089.sb, 37310368
Journal of aerosol medicine and pulmonary drug delivery, 36, 3, 144-151, 10.1089/jamp.2023.29089.sb, 37310368
Influence of particle size and material properties on mucociliary clearance from the airways
Publication
Henning A,
Schneider M,
Nafee N,
Muijs L,
Rytting E,
Wang X,
Kissel T,
Grafahrend D,
Klee D,
Lehr C
(2010)
Journal of aerosol medicine and pulmonary drug delivery, 23, 4, 233-241, 10.1089/jamp.2009.0806
Journal of aerosol medicine and pulmonary drug delivery, 23, 4, 233-241, 10.1089/jamp.2009.0806
Metabolic profiling of S-praziquantel: Structure elucidation using the crystalline sponge method in combination with mass spectrometry and nuclear magnetic resonance
Publication
Rosenberger L,
Jenniches J,
Essen C,
Khutia A,
Kühn C,
Marx A,
Georgi K,
Hirsch A,
Hartmann R,
Badolo L
(2022)
Drug metabolism and disposition: the biological fate of chemicals, 10.1124/dmd.121.000663, 35115299
Drug metabolism and disposition: the biological fate of chemicals, 10.1124/dmd.121.000663, 35115299
About
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Who we are The Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) was established in August 2009 in collaboration between the Helmholtz Centre for Infection Research (HZI) and the Saarlan
Management
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Management Institute Management Administrative Team Scientific Advisory Board Since its foundation in 2009, Prof. Rolf Müller leads the HIPS as its Managing Director. Since 2019, Dr. Stephanie Thomas
Optical tweezers reveal relationship between microstructure and nanoparticle penetration of pulmonary mucus
Publication
Kirch J,
Schneider A,
Abou B,
Hopf A,
Schaefer U,
Schneider M,
Schall C,
Wagner C,
Lehr C
(2012)
Proceedings of the National Academy of Sciences of the United States of America, 109, 45, 18355-18360, 10.1073/pnas.1214066109
Proceedings of the National Academy of Sciences of the United States of America, 109, 45, 18355-18360, 10.1073/pnas.1214066109