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A Monoclonal Human Alveolar Epithelial Cell Line ("Arlo") with Pronounced Barrier Function for Studying Drug Permeability and Viral Infections
Publication
Carius P,
Jungmann A,
Bechtel M,
Grißmer A,
Boese A,
Gasparoni G,
Salhab A,
Seipelt R,
Urbschat K,
Richter C,
Meier C,
Bojkova D,
Cinatl J,
Walter J,
Schneider-Daum N,
Lehr C
(2023)
Adv. Sci., 10, 8, 10.1002/advs.202207301, 36748276
Adv. Sci., 10, 8, 10.1002/advs.202207301, 36748276
Second Generation Tiancimycin-Based Antibody–Drug Conjugates Enabled by Highly Efficient Semi-synthetic Approach Specifically Targeting B-Cell Malignancies
Publication
Kiefer A,
Thirugnanasambantham P,
Jin Y,
Steele A,
Hwang D,
Jiang Y,
Adhikari A,
Yang D,
Chang J,
Tafesse R,
Rader C,
Muthusamy N,
Shen B
(2025)
JACS Au, 10.1021/jacsau.5c00353
JACS Au, 10.1021/jacsau.5c00353
Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin: Fragment-Based Drug Design Facilitated by Dynamic Combinatorial Chemistry
Publication
Mondal M,
Radeva N,
Fanlo-Virgós H,
Otto S,
Klebe G,
Hirsch A
(2016)
Angewandte Chemie (International ed. in English), 55, 32, 9422-6, 10.1002/anie.201603074, 27400756
Angewandte Chemie (International ed. in English), 55, 32, 9422-6, 10.1002/anie.201603074, 27400756
Applications of Raman spectroscopy in skin research--From skin physiology and diagnosis up to risk assessment and dermal drug delivery
Publication
Franzen L,
Windbergs M
(2015)
Advanced Drug Delivery Reviews, 89, 91-104, 10.1016/j.addr.2015.04.002, 25868454
Advanced Drug Delivery Reviews, 89, 91-104, 10.1016/j.addr.2015.04.002, 25868454
Nano- and microscaled particles for drug targeting to inflamed intestinal mucosa - A first in vivo study in human patients
Publication
Schmidt C,
Lautenschlaeger C,
Collnot E,
Schumann M,
Bojarski C,
Schulzke J,
Lehr C,
Stallmach A
(2013)
Journal of Controlled Release, 165, 2, 139-145, 10.1016/j.jconrel.2012.10.019, 23127508
Journal of Controlled Release, 165, 2, 139-145, 10.1016/j.jconrel.2012.10.019, 23127508
Non-invasive insight into the release mechanisms of a poorly soluble drug from amorphous solid dispersions by confocal Raman microscopy
Publication
Puncochová K,
Vukosavljevic B,
Hanuš J,
Beránek J,
Windbergs M,
Štepánek F
(2016)
European Journal of Pharmaceutics and Biopharmaceutics, 101, 119-25, 10.1016/j.ejpb.2016.02.001, 26861928
European Journal of Pharmaceutics and Biopharmaceutics, 101, 119-25, 10.1016/j.ejpb.2016.02.001, 26861928
Application of a Biocatalytic Strategy for the Preparation of Tiancimycin-Based Antibody-Drug Conjugates Revealing Key Insights into Structure-Activity Relationships
Publication
Steele A,
Kiefer A,
Hwang D,
Yang D,
Teijaro C,
Adhikari A,
Rader C,
Shen B
(2023)
Journal of medicinal chemistry, 66, 2, 1562-1573, 10.1021/acs.jmedchem.2c01771, 36599039
Journal of medicinal chemistry, 66, 2, 1562-1573, 10.1021/acs.jmedchem.2c01771, 36599039
Ciprofloxacin-loaded lipid-core nanocapsules as mucus penetrating drug delivery system intended for the treatment of bacterial infections in cystic fibrosis
Publication
Torge A,
Wagner S,
Chaves P,
Oliveira E,
Guterres S,
Pohlmann A,
Titz A,
Schneider M,
Beck R
(2017)
Int J Pharm, 527, 1-2, 92-102, 10.1016/j.ijpharm.2017.05.013, 28499793
Int J Pharm, 527, 1-2, 92-102, 10.1016/j.ijpharm.2017.05.013, 28499793
A new cell line-based coculture model of the human air-blood barrier to evaluate the interaction with aerosolized drug carriers
Publication
Kletting S
(2016)
Book
Book
Fragment-Based Drug Design Facilitated by Protein-Templated Click Chemistry: Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin
Publication
Mondal M,
Unver M,
Pal A,
Bakker M,
Berrier S,
Hirsch A
(2016)
Chem. Eur. J., 22, 42, 14826-14830, 10.1002/chem.201603001, 27604032
Chem. Eur. J., 22, 42, 14826-14830, 10.1002/chem.201603001, 27604032