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Non-invasive insight into the release mechanisms of a poorly soluble drug from amorphous solid dispersions by confocal Raman microscopy
Publication
Puncochová K,
Vukosavljevic B,
Hanuš J,
Beránek J,
Windbergs M,
Štepánek F
(2016)
European Journal of Pharmaceutics and Biopharmaceutics, 101, 119-25, 10.1016/j.ejpb.2016.02.001, 26861928
European Journal of Pharmaceutics and Biopharmaceutics, 101, 119-25, 10.1016/j.ejpb.2016.02.001, 26861928
Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin: Fragment-Based Drug Design Facilitated by Dynamic Combinatorial Chemistry
Publication
Mondal M,
Radeva N,
Fanlo-Virgós H,
Otto S,
Klebe G,
Hirsch A
(2016)
Angewandte Chemie (International ed. in English), 55, 32, 9422-6, 10.1002/anie.201603074, 27400756
Angewandte Chemie (International ed. in English), 55, 32, 9422-6, 10.1002/anie.201603074, 27400756
Applications of Raman spectroscopy in skin research--From skin physiology and diagnosis up to risk assessment and dermal drug delivery
Publication
Franzen L,
Windbergs M
(2015)
Advanced Drug Delivery Reviews, 89, 91-104, 10.1016/j.addr.2015.04.002, 25868454
Advanced Drug Delivery Reviews, 89, 91-104, 10.1016/j.addr.2015.04.002, 25868454
Ciprofloxacin-loaded lipid-core nanocapsules as mucus penetrating drug delivery system intended for the treatment of bacterial infections in cystic fibrosis
Publication
Torge A,
Wagner S,
Chaves P,
Oliveira E,
Guterres S,
Pohlmann A,
Titz A,
Schneider M,
Beck R
(2017)
Int J Pharm, 527, 1-2, 92-102, 10.1016/j.ijpharm.2017.05.013, 28499793
Int J Pharm, 527, 1-2, 92-102, 10.1016/j.ijpharm.2017.05.013, 28499793
A new cell line-based coculture model of the human air-blood barrier to evaluate the interaction with aerosolized drug carriers
Publication
Kletting S
(2016)
Book
Book
Fragment-Based Drug Design Facilitated by Protein-Templated Click Chemistry: Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin
Publication
Mondal M,
Unver M,
Pal A,
Bakker M,
Berrier S,
Hirsch A
(2016)
Chem. Eur. J., 22, 42, 14826-14830, 10.1002/chem.201603001, 27604032
Chem. Eur. J., 22, 42, 14826-14830, 10.1002/chem.201603001, 27604032
Discovery of novel drug-like antitubercular hits targeting the MEP pathway enzyme DXPS by strategic application of ligand-based virtual screening
Publication
Di Zhu,
Johannsen S,
Masini T,
Simonin C,
Haupenthal J,
Illarionov B,
Andreas A,
Awale M,
Gierse R,
van der Laan T,
van der Vlag R,
Nasti R,
Poizat M,
Buhler E,
Reiling N,
Müller R,
Fischer M,
Reymond J,
Hirsch A
(2022)
Chem. Sci., 13, 36, 10686-10698, 10.1039/D2SC02371G, 36320685
Chem. Sci., 13, 36, 10686-10698, 10.1039/D2SC02371G, 36320685
Application of a Biocatalytic Strategy for the Preparation of Tiancimycin-Based Antibody-Drug Conjugates Revealing Key Insights into Structure-Activity Relationships
Publication
Steele A,
Kiefer A,
Hwang D,
Yang D,
Teijaro C,
Adhikari A,
Rader C,
Shen B
(2023)
Journal of medicinal chemistry, 66, 2, 1562-1573, 10.1021/acs.jmedchem.2c01771, 36599039
Journal of medicinal chemistry, 66, 2, 1562-1573, 10.1021/acs.jmedchem.2c01771, 36599039
A new Pharmaceutical Aerosol Deposition Device on Cell Cultures (PADDOCC) to evaluate pulmonary drug absorption for metered dose dry powder formulations
Publication
Hein S,
Bur M,
Schaefer U,
Lehr C
(2011)
European Journal of Pharmaceutics and Biopharmaceutics, 77, 1, 132-138, 10.1016/j.ejpb.2010.10.003
European Journal of Pharmaceutics and Biopharmaceutics, 77, 1, 132-138, 10.1016/j.ejpb.2010.10.003
3D air-liquid interface culture of Cystic Fibrosis bronchial epithelia, macrophages and P. aeruginosa to assess host-pathogen interaction and drug efficacy
Publication
Montefusco C,
Montefusco-Pereira C
(2020)
Book, 10.22028/D291-31815
Book, 10.22028/D291-31815