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The virulence factor LecB varies in clinical isolates: consequences for ligand binding and drug discovery
Publication
Sommer R,
Wagner S,
Varrot A,
Nycholat C,
Khaledi A,
Häussler S,
Paulson J,
Imberty A,
Titz A
(2016)
Chem Sci, 7, 8, 4990-5001, 10.1039/c6sc00696e, 30155149
Chem Sci, 7, 8, 4990-5001, 10.1039/c6sc00696e, 30155149
In situ drug release monitoring with a fiber-optic system: Overcoming matrix interferences using derivative spectrophotometry
Publication
Guillot A,
Limberge M,
Krämer J,
Lehr C
(2013)
Dissolution Technologies, 20, 2, 15-19
Dissolution Technologies, 20, 2, 15-19
The Parkinson's Disease Drug Tolcapone and Analogues are Potent Glycomimetic Lectin Inhibitors of Pseudomonas aeruginosa LecA
Publication
Leusmann S,
Siebs E,
Kuhaudomlarp S,
Varrot A,
Imberty A,
Kuhn B,
Lerner C,
Grether U,
Titz A
(2025)
Angewandte Chemie (International ed. in English), 64, 50, 10.1002/anie.202508864, 41178200
Angewandte Chemie (International ed. in English), 64, 50, 10.1002/anie.202508864, 41178200
Drug solubility in biorelevant media in the context of an inhalation-based biopharmaceutics classification system (iBCS)
Publication
Floroiu A,
Loretz B,
Krämer J,
Lehr C
(2024)
Eur J Pharm Biopharm, 197, 10.1016/j.ejpb.2024.114206, 38316234
Eur J Pharm Biopharm, 197, 10.1016/j.ejpb.2024.114206, 38316234
Zebrafish: An Attractive Model to Study Staphylococcus aureus Infection and Its Use as a Drug Discovery Tool
Publication
Rasheed S,
Fries F,
Müller R,
Herrmann J
(2021)
Pharmaceuticals, 14, 6, 10.3390/ph14060594
Pharmaceuticals, 14, 6, 10.3390/ph14060594
3D printed tablets loaded with polymeric nanocapsules: An innovative approach to produce customized drug delivery systems
Publication
Beck R,
Chaves P,
Goyanes A,
Vukosavljevic B,
Buanz A,
Windbergs M,
Basit A,
Gaisford S
(2017)
International journal of pharmaceutics, 528, 1-2, 268-279, 10.1016/j.ijpharm.2017.05.074, 28583328
International journal of pharmaceutics, 528, 1-2, 268-279, 10.1016/j.ijpharm.2017.05.074, 28583328
Compounds Interfering with Embryonic Lethal Abnormal Vision (ELAV) Protein-RNA Complexes: An Avenue for Discovering New Drugs
Publication
Nasti R,
Rossi D,
Amadio M,
Pascale A,
Unver M,
Hirsch A,
Collina S
(2017)
Journal of medicinal chemistry, 60, 20, 8257-8267, 10.1021/acs.jmedchem.6b01871, 28587461
Journal of medicinal chemistry, 60, 20, 8257-8267, 10.1021/acs.jmedchem.6b01871, 28587461
Solid Phase Extraction as an Innovative Separation Method for Measuring Free and Entrapped Drug in Lipid Nanoparticles
Publication
Guillot A,
Couffin A,
Sejean X,
Navarro F,
Limberger M,
Lehr C
(2015)
Pharmaceutical research, 32, 12, 3999-4009, 10.1007/s11095-015-1761-8
Pharmaceutical research, 32, 12, 3999-4009, 10.1007/s11095-015-1761-8
Preclinical safety and efficacy models for pulmonary drug delivery of antimicrobials with focus on in vitro models
Publication
Hittinger M,
Juntke J,
Kletting S,
Schneider-Daum N,
de Souza Carvalho C,
Lehr C
(2015)
Advanced Drug Delivery Reviews, 85, 44-56, 10.1016/j.addr.2014.10.011, 25453270
Advanced Drug Delivery Reviews, 85, 44-56, 10.1016/j.addr.2014.10.011, 25453270
Drug transport across pulmonary epithelial cell monolayers: effects of particle size, apical liquid volume, and deposition technique
Publication
Bur M,
Huwer H,
Muys L,
Lehr C
(2010)
Journal of aerosol medicine and pulmonary drug delivery, 23, 3, 119-27, 10.1089/jamp.2009.0757, 20073555
Journal of aerosol medicine and pulmonary drug delivery, 23, 3, 119-27, 10.1089/jamp.2009.0757, 20073555