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Pulmonary drug delivery: From generating aerosols to overcoming biological barriers-therapeutic possibilities and technological challenges
Publication
Ruge C,
Kirch J,
Lehr C
(2013)
The Lancet Respiratory Medicine, 1, 5, 402-413, 10.1016/S2213-2600(13)70072-9, 24429205
The Lancet Respiratory Medicine, 1, 5, 402-413, 10.1016/S2213-2600(13)70072-9, 24429205
Influence of the application area on finite dose permeation in relation to drug type applied
Publication
Hahn T,
Selzer D,
Neumann D,
Kostka K,
Lehr C,
Schaefer U
(2012)
Experimental Dermatology, 21, 3, 233-235, 10.1111/j.1600-0625.2011.01424.x
Experimental Dermatology, 21, 3, 233-235, 10.1111/j.1600-0625.2011.01424.x
Soluplus® as an effective absorption enhancer of poorly soluble drugs in vitro and in vivo
Publication
Linn M,
Collnot E,
Djuric D,
Hempel K,
Fabian E,
Kolter K,
Lehr C
(2012)
European Journal of Pharmaceutical Sciences, 45, 3, 336-343, 10.1016/j.ejps.2011.11.025
European Journal of Pharmaceutical Sciences, 45, 3, 336-343, 10.1016/j.ejps.2011.11.025
A stretchable human lung‐on‐chip model of alveolar inflammation for evaluating anti‐inflammatory drug response
Publication
Richter C,
Latta L,
Harig D,
Carius P,
Stucki J,
Hobi N,
Hugi A,
Schumacher P,
Krebs T,
Gamrekeli A,
Stöckle F,
Urbschat K,
Montalvo G,
Lautenschläger F,
Loretz B,
Hidalgo A,
Schneider-Daum N,
Lehr C
(2024)
Bioengineering & Transla Med, 10.1002/btm2.10715
Bioengineering & Transla Med, 10.1002/btm2.10715
Cell and tissue-based in vitro models for improving the development of oral inhalation drug products
Publication
Hittinger M,
Schneider-Daum N,
Lehr C
(2017)
European Journal of Pharmaceutics and Biopharmaceutics, 118, 73-78, 10.1016/j.ejpb.2017.02.019
European Journal of Pharmaceutics and Biopharmaceutics, 118, 73-78, 10.1016/j.ejpb.2017.02.019
The virulence factor LecB varies in clinical isolates: consequences for ligand binding and drug discovery
Publication
Sommer R,
Wagner S,
Varrot A,
Nycholat C,
Khaledi A,
Häussler S,
Paulson J,
Imberty A,
Titz A
(2016)
Chem Sci, 7, 8, 4990-5001, 10.1039/c6sc00696e, 30155149
Chem Sci, 7, 8, 4990-5001, 10.1039/c6sc00696e, 30155149
The synergistic effect of chlorotoxin-mApoE in boosting drug-loaded liposomes across the BBB
Publication
Formicola B,
Dal Magro R,
Montefusco-Pereira C,
Lehr C,
Koch M,
Russo L,
Grasso G,
Deriu M,
Danani A,
Bourdoulous S,
Re F
(2019)
Journal of nanobiotechnology, 17, 1, 10.1186/s12951-019-0546-3, 31711496
Journal of nanobiotechnology, 17, 1, 10.1186/s12951-019-0546-3, 31711496
In situ drug release monitoring with a fiber-optic system: Overcoming matrix interferences using derivative spectrophotometry
Publication
Guillot A,
Limberge M,
Krämer J,
Lehr C
(2013)
Dissolution Technologies, 20, 2, 15-19
Dissolution Technologies, 20, 2, 15-19
Drug solubility in biorelevant media in the context of an inhalation-based biopharmaceutics classification system (iBCS)
Publication
Floroiu A,
Loretz B,
Krämer J,
Lehr C
(2024)
Eur J Pharm Biopharm, 197, 10.1016/j.ejpb.2024.114206, 38316234
Eur J Pharm Biopharm, 197, 10.1016/j.ejpb.2024.114206, 38316234
Zebrafish: An Attractive Model to Study Staphylococcus aureus Infection and Its Use as a Drug Discovery Tool
Publication
Rasheed S,
Fries F,
Müller R,
Herrmann J
(2021)
Pharmaceuticals, 14, 6, 10.3390/ph14060594
Pharmaceuticals, 14, 6, 10.3390/ph14060594