Search
The role of mucus on drug transport and its potential to affect therapeutic outcomes
Publication
Murgia X,
Loretz B,
Hartwig O,
Hittinger M,
Lehr C
(2018)
Advanced Drug Delivery Reviews, 124, 82-97, 10.1016/j.addr.2017.10.009, 29106910
Advanced Drug Delivery Reviews, 124, 82-97, 10.1016/j.addr.2017.10.009, 29106910
Directing Drugs to Bugs: Antibiotic-Carbohydrate Conjugates Targeting Biofilm-Associated Lectins of Pseudomonas aeruginosa
Publication
Meiers J,
Zahorska E,
Röhrig T,
Hauck D,
Wagner S,
Titz A
(2020)
Journal of medicinal chemistry, 63, 20, 11707-11724, 10.1021/acs.jmedchem.0c00856, 32924479
Journal of medicinal chemistry, 63, 20, 11707-11724, 10.1021/acs.jmedchem.0c00856, 32924479
Raman microscopy for cellular investigations--From single cell imaging to drug carrier uptake visualization
Publication
Kann B,
Offerhaus H,
Windbergs M,
Otto C
(2015)
Advanced Drug Delivery Reviews, 89, 71-90, 10.1016/j.addr.2015.02.006, 25728764
Advanced Drug Delivery Reviews, 89, 71-90, 10.1016/j.addr.2015.02.006, 25728764
Design of Poly-Catechol Biodynamers for Potentiation of Antibiotic Efficacy against Drug-Resistant Bacteria
Publication
Zeroug-Metz L,
Shehu K,
Bassil J,
Podlecki J,
Sonntag P,
Koch M,
Christoulaki A,
Buhler E,
Hirsch A,
Kraegeloh A,
Schneider M,
Lee S
(2026)
Biomacromolecules, 27, 3, 1949-1968, 10.1021/acs.biomac.5c02130, 41730198
Biomacromolecules, 27, 3, 1949-1968, 10.1021/acs.biomac.5c02130, 41730198
DVD-IgG1 antibody-drug conjugates: Expanding the landscape of targeted cancer therapy
Publication
Kiefer A,
Steele A,
Rader C,
Shen B
(2026)
Current opinion in chemical biology, 92, 10.1016/j.cbpa.2026.102653, 41734646
Current opinion in chemical biology, 92, 10.1016/j.cbpa.2026.102653, 41734646
Targeting the Energy-Coupling Factor Transporters: A Novel Antibiotic Drug Target in Streptococcus pneumoniae
Publication
Diamanti E,
Cremers A,
Li Y,
Exapicheidou I,
Baumann C,
Gibson P,
Shams A,
Martin L,
Becker R,
Setyawati I,
Zeimetz L,
Haupenthal J,
Witschel M,
Slotboom D,
Herrmann J,
Rox K,
Hamed M,
Veening J,
Hirsch A
(2026)
J. Med. Chem., 10.1021/acs.jmedchem.5c03638, 42284150
J. Med. Chem., 10.1021/acs.jmedchem.5c03638, 42284150
The Non-Mevalonate Pathway to Isoprenoid Biosynthesis: A Potential Source of New Drug Targets
Publication
Hirsch A,
Diederich F
(2008)
CHIMIA, 62, 4, 226-230, 10.2533/chimia.2008.226
CHIMIA, 62, 4, 226-230, 10.2533/chimia.2008.226
Consistent Prediction of Mutation Effect on Drug Binding in HIV-1 Protease Using Alchemical Calculations
Publication
Bastys T,
Gapsys V,
Doncheva N,
Kaiser R,
Groot B,
Kalinina O
(2018)
Journal of chemical theory and computation, 14, 7, 3397-3408, 10.1021/acs.jctc.7b01109, 29847122
Journal of chemical theory and computation, 14, 7, 3397-3408, 10.1021/acs.jctc.7b01109, 29847122
Human microbial metabolite mimicry as a strategy to expand the chemical space of potential drugs
Publication
Li H,
Ranhotra H,
Mani S,
Dvorák Z,
Sokol H,
Müller R
(2020)
Drug Discov. Today, 25, 9, 1575-1579, 10.1016/j.drudis.2020.06.007, 32562605
Drug Discov. Today, 25, 9, 1575-1579, 10.1016/j.drudis.2020.06.007, 32562605
Drug Administration Routes Impact the Metabolism of a Synthetic Cannabinoid in the Zebrafish Larvae Model
Publication
Park Y,
Meyer M,
Müller R,
Herrmann J
(2020)
Molecules, 25, 19, 10.3390/molecules25194474
Molecules, 25, 19, 10.3390/molecules25194474