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Facile Production of the Pseudomonas aeruginosa Virulence Factor LasB in E. coli for Structure-Based Drug Design
Publication
Kolling D,
Haupenthal J,
Hirsch A,
Köhnke J
(2023)
ChemBioChem, 10.1002/cbic.202300185, 37195753
ChemBioChem, 10.1002/cbic.202300185, 37195753
Models using native tracheobronchial mucus in the context of pulmonary drug delivery research: Composition, structure and barrier properties
Publication
Huck B,
Murgia X,
Frisch S,
Hittinger M,
Hidalgo A,
Loretz B,
Lehr C
(2022)
Advanced Drug Delivery Reviews, 183, 10.1016/j.addr.2022.114141, 35149123
Advanced Drug Delivery Reviews, 183, 10.1016/j.addr.2022.114141, 35149123
A Custom-Made Device for Reproducibly Depositing Pre-metered Doses of Nebulized Drugs on Pulmonary Cells in vitro
Publication
Horstmann J,
Thorn C,
Carius P,
Graef F,
Murgia X,
Souza Carvalho-Wodarz C,
Lehr C
(2021)
Frontiers in Bioengineering and Biotechnology, 9, 10.3389/fbioe.2021.643491, 33968912
Frontiers in Bioengineering and Biotechnology, 9, 10.3389/fbioe.2021.643491, 33968912
A Monoclonal Human Alveolar Epithelial Cell Line ("Arlo") with Pronounced Barrier Function for Studying Drug Permeability and Viral Infections
Publication
Carius P,
Jungmann A,
Bechtel M,
Grißmer A,
Boese A,
Gasparoni G,
Salhab A,
Seipelt R,
Urbschat K,
Richter C,
Meier C,
Bojkova D,
Cinatl J,
Walter J,
Schneider-Daum N,
Lehr C
(2023)
Adv. Sci., 10, 8, 10.1002/advs.202207301, 36748276
Adv. Sci., 10, 8, 10.1002/advs.202207301, 36748276
Drug delivery to the inflamed intestinal mucosa- targeting technologies and human cell culture models for better therapies of IBD
Publication
Olga H,
Shetab Boushehri Maryam A,
Shalaby Karim S,
Brigitta L,
Alf L,
Claus-Michael L
(2021)
Advanced Drug Delivery Reviews, 10.1016/j.addr.2021.113828, 34157320
Advanced Drug Delivery Reviews, 10.1016/j.addr.2021.113828, 34157320
Carrier interactions with the biological barriers of the lung: Advanced in vitro models and challenges for pulmonary drug delivery
Publication
de Souza Carvalho C,
Daum N,
Lehr C
(2014)
Advanced Drug Delivery Reviews, 75, 129-140, 10.1016/j.addr.2014.05.014, 24880145
Advanced Drug Delivery Reviews, 75, 129-140, 10.1016/j.addr.2014.05.014, 24880145
Non-invasive insight into the release mechanisms of a poorly soluble drug from amorphous solid dispersions by confocal Raman microscopy
Publication
Puncochová K,
Vukosavljevic B,
Hanuš J,
Beránek J,
Windbergs M,
Štepánek F
(2016)
European Journal of Pharmaceutics and Biopharmaceutics, 101, 119-25, 10.1016/j.ejpb.2016.02.001, 26861928
European Journal of Pharmaceutics and Biopharmaceutics, 101, 119-25, 10.1016/j.ejpb.2016.02.001, 26861928
Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin: Fragment-Based Drug Design Facilitated by Dynamic Combinatorial Chemistry
Publication
Mondal M,
Radeva N,
Fanlo-Virgós H,
Otto S,
Klebe G,
Hirsch A
(2016)
Angewandte Chemie (International ed. in English), 55, 32, 9422-6, 10.1002/anie.201603074, 27400756
Angewandte Chemie (International ed. in English), 55, 32, 9422-6, 10.1002/anie.201603074, 27400756
Applications of Raman spectroscopy in skin research--From skin physiology and diagnosis up to risk assessment and dermal drug delivery
Publication
Franzen L,
Windbergs M
(2015)
Advanced Drug Delivery Reviews, 89, 91-104, 10.1016/j.addr.2015.04.002, 25868454
Advanced Drug Delivery Reviews, 89, 91-104, 10.1016/j.addr.2015.04.002, 25868454
Nano- and microscaled particles for drug targeting to inflamed intestinal mucosa - A first in vivo study in human patients
Publication
Schmidt C,
Lautenschlaeger C,
Collnot E,
Schumann M,
Bojarski C,
Schulzke J,
Lehr C,
Stallmach A
(2013)
Journal of Controlled Release, 165, 2, 139-145, 10.1016/j.jconrel.2012.10.019, 23127508
Journal of Controlled Release, 165, 2, 139-145, 10.1016/j.jconrel.2012.10.019, 23127508