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Cell and tissue-based in vitro models for improving the development of oral inhalation drug products
Publication
Hittinger M,
Schneider-Daum N,
Lehr C
(2017)
European Journal of Pharmaceutics and Biopharmaceutics, 118, 73-78, 10.1016/j.ejpb.2017.02.019
European Journal of Pharmaceutics and Biopharmaceutics, 118, 73-78, 10.1016/j.ejpb.2017.02.019
The virulence factor LecB varies in clinical isolates: consequences for ligand binding and drug discovery
Publication
Sommer R,
Wagner S,
Varrot A,
Nycholat C,
Khaledi A,
Häussler S,
Paulson J,
Imberty A,
Titz A
(2016)
Chem Sci, 7, 8, 4990-5001, 10.1039/c6sc00696e, 30155149
Chem Sci, 7, 8, 4990-5001, 10.1039/c6sc00696e, 30155149
In situ drug release monitoring with a fiber-optic system: Overcoming matrix interferences using derivative spectrophotometry
Publication
Guillot A,
Limberge M,
Krämer J,
Lehr C
(2013)
Dissolution Technologies, 20, 2, 15-19
Dissolution Technologies, 20, 2, 15-19
Drug solubility in biorelevant media in the context of an inhalation-based biopharmaceutics classification system (iBCS)
Publication
Floroiu A,
Loretz B,
Krämer J,
Lehr C
(2024)
Eur J Pharm Biopharm, 197, 10.1016/j.ejpb.2024.114206, 38316234
Eur J Pharm Biopharm, 197, 10.1016/j.ejpb.2024.114206, 38316234
Zebrafish: An Attractive Model to Study Staphylococcus aureus Infection and Its Use as a Drug Discovery Tool
Publication
Rasheed S,
Fries F,
Müller R,
Herrmann J
(2021)
Pharmaceuticals, 14, 6, 10.3390/ph14060594
Pharmaceuticals, 14, 6, 10.3390/ph14060594
3D printed tablets loaded with polymeric nanocapsules: An innovative approach to produce customized drug delivery systems
Publication
Beck R,
Chaves P,
Goyanes A,
Vukosavljevic B,
Buanz A,
Windbergs M,
Basit A,
Gaisford S
(2017)
International journal of pharmaceutics, 528, 1-2, 268-279, 10.1016/j.ijpharm.2017.05.074, 28583328
International journal of pharmaceutics, 528, 1-2, 268-279, 10.1016/j.ijpharm.2017.05.074, 28583328
Compounds Interfering with Embryonic Lethal Abnormal Vision (ELAV) Protein-RNA Complexes: An Avenue for Discovering New Drugs
Publication
Nasti R,
Rossi D,
Amadio M,
Pascale A,
Unver M,
Hirsch A,
Collina S
(2017)
Journal of medicinal chemistry, 60, 20, 8257-8267, 10.1021/acs.jmedchem.6b01871, 28587461
Journal of medicinal chemistry, 60, 20, 8257-8267, 10.1021/acs.jmedchem.6b01871, 28587461
Solid Phase Extraction as an Innovative Separation Method for Measuring Free and Entrapped Drug in Lipid Nanoparticles
Publication
Guillot A,
Couffin A,
Sejean X,
Navarro F,
Limberger M,
Lehr C
(2015)
Pharmaceutical research, 32, 12, 3999-4009, 10.1007/s11095-015-1761-8
Pharmaceutical research, 32, 12, 3999-4009, 10.1007/s11095-015-1761-8
Preclinical safety and efficacy models for pulmonary drug delivery of antimicrobials with focus on in vitro models
Publication
Hittinger M,
Juntke J,
Kletting S,
Schneider-Daum N,
de Souza Carvalho C,
Lehr C
(2015)
Advanced Drug Delivery Reviews, 85, 44-56, 10.1016/j.addr.2014.10.011, 25453270
Advanced Drug Delivery Reviews, 85, 44-56, 10.1016/j.addr.2014.10.011, 25453270
Drug transport across pulmonary epithelial cell monolayers: effects of particle size, apical liquid volume, and deposition technique
Publication
Bur M,
Huwer H,
Muys L,
Lehr C
(2010)
Journal of aerosol medicine and pulmonary drug delivery, 23, 3, 119-27, 10.1089/jamp.2009.0757, 20073555
Journal of aerosol medicine and pulmonary drug delivery, 23, 3, 119-27, 10.1089/jamp.2009.0757, 20073555