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Consistent Prediction of Mutation Effect on Drug Binding in HIV-1 Protease Using Alchemical Calculations
Publication
Bastys T,
Gapsys V,
Doncheva N,
Kaiser R,
Groot B,
Kalinina O
(2018)
Journal of chemical theory and computation, 14, 7, 3397-3408, 10.1021/acs.jctc.7b01109, 29847122
Journal of chemical theory and computation, 14, 7, 3397-3408, 10.1021/acs.jctc.7b01109, 29847122
In vitro models for evaluating safety and efficacy of novel technologies for skin drug delivery
Publication
Planz V,
Lehr C,
Windbergs M
(2016)
Journal of Controlled Release, 242, 89-104, 10.1016/j.jconrel.2016.09.002
Journal of Controlled Release, 242, 89-104, 10.1016/j.jconrel.2016.09.002
Label-free analysis of drug delivery systems and cellular interaction studies using confocal Raman microscopy
Publication
Kann B
(2016)
Book
Book
Combinatorial tuning of peptidic drug candidates: high-affinity matriptase inhibitors through incremental structure-guided optimization
Publication
Fittler H,
Avrutina O,
Glotzbach B,
Empting M,
Kolmar H
(2013)
Org. Biomol. Chem., 11, 11, 1848-57, 10.1039/c3ob27469a, 23361403
Org. Biomol. Chem., 11, 11, 1848-57, 10.1039/c3ob27469a, 23361403
Biopharmaceutical in vitro characterization of CPZEN-45, a drug candidate for inhalation therapy of tuberculosis
Publication
Salomon J,
Galeron P,
Schulte N,
Morow P,
Severynse-Stevens D,
Huwer H,
Daum N,
Lehr C,
Hickey A,
Ehrhardt C
(2013)
Therapeutic delivery, 4, 8, 915-923, 10.4155/tde.13.62
Therapeutic delivery, 4, 8, 915-923, 10.4155/tde.13.62
Pulmonary drug delivery: From generating aerosols to overcoming biological barriers-therapeutic possibilities and technological challenges
Publication
Ruge C,
Kirch J,
Lehr C
(2013)
The Lancet Respiratory Medicine, 1, 5, 402-413, 10.1016/S2213-2600(13)70072-9, 24429205
The Lancet Respiratory Medicine, 1, 5, 402-413, 10.1016/S2213-2600(13)70072-9, 24429205
Influence of the application area on finite dose permeation in relation to drug type applied
Publication
Hahn T,
Selzer D,
Neumann D,
Kostka K,
Lehr C,
Schaefer U
(2012)
Experimental Dermatology, 21, 3, 233-235, 10.1111/j.1600-0625.2011.01424.x
Experimental Dermatology, 21, 3, 233-235, 10.1111/j.1600-0625.2011.01424.x
Soluplus® as an effective absorption enhancer of poorly soluble drugs in vitro and in vivo
Publication
Linn M,
Collnot E,
Djuric D,
Hempel K,
Fabian E,
Kolter K,
Lehr C
(2012)
European Journal of Pharmaceutical Sciences, 45, 3, 336-343, 10.1016/j.ejps.2011.11.025
European Journal of Pharmaceutical Sciences, 45, 3, 336-343, 10.1016/j.ejps.2011.11.025
A stretchable human lung‐on‐chip model of alveolar inflammation for evaluating anti‐inflammatory drug response
Publication
Richter C,
Latta L,
Harig D,
Carius P,
Stucki J,
Hobi N,
Hugi A,
Schumacher P,
Krebs T,
Gamrekeli A,
Stöckle F,
Urbschat K,
Montalvo G,
Lautenschläger F,
Loretz B,
Hidalgo A,
Schneider-Daum N,
Lehr C
(2024)
Bioengineering & Transla Med, 10.1002/btm2.10715
Bioengineering & Transla Med, 10.1002/btm2.10715
The synergistic effect of chlorotoxin-mApoE in boosting drug-loaded liposomes across the BBB
Publication
Formicola B,
Dal Magro R,
Montefusco-Pereira C,
Lehr C,
Koch M,
Russo L,
Grasso G,
Deriu M,
Danani A,
Bourdoulous S,
Re F
(2019)
Journal of nanobiotechnology, 17, 1, 10.1186/s12951-019-0546-3, 31711496
Journal of nanobiotechnology, 17, 1, 10.1186/s12951-019-0546-3, 31711496